The role of apolipoprotein E in bone metabolism.
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The role of apolipoprotein E in bone metabolism. / Niemeier, Andreas; Schinke, Thorsten; Heeren, Jörg; Amling, Michael.
in: BONE, Jahrgang 50, Nr. 2, 2, 2012, S. 518-524.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - The role of apolipoprotein E in bone metabolism.
AU - Niemeier, Andreas
AU - Schinke, Thorsten
AU - Heeren, Jörg
AU - Amling, Michael
PY - 2012
Y1 - 2012
N2 - Apolipoprotein E (apoE) is a major structural apolipoprotein of several lipoprotein classes. Over the last 13 years, numerous studies have focused on the question whether human apoE affects bone phenotypes and, more recently, whether apoE regulates bone metabolism in mice. Here, we first provide a brief background introduction into the structure, established physiological and pathophysiological functions of apoE, and will then discuss the new aspects of the emerging role of apoE in bone.
AB - Apolipoprotein E (apoE) is a major structural apolipoprotein of several lipoprotein classes. Over the last 13 years, numerous studies have focused on the question whether human apoE affects bone phenotypes and, more recently, whether apoE regulates bone metabolism in mice. Here, we first provide a brief background introduction into the structure, established physiological and pathophysiological functions of apoE, and will then discuss the new aspects of the emerging role of apoE in bone.
KW - Animals
KW - Humans
KW - Genetic Predisposition to Disease
KW - Protein Isoforms/genetics/metabolism
KW - Apolipoproteins E/genetics/metabolism
KW - Bone Density/genetics
KW - Bone and Bones/metabolism
KW - Fractures, Bone/complications/ethnology/genetics
KW - Animals
KW - Humans
KW - Genetic Predisposition to Disease
KW - Protein Isoforms/genetics/metabolism
KW - Apolipoproteins E/genetics/metabolism
KW - Bone Density/genetics
KW - Bone and Bones/metabolism
KW - Fractures, Bone/complications/ethnology/genetics
M3 - SCORING: Journal article
VL - 50
SP - 518
EP - 524
JO - BONE
JF - BONE
SN - 8756-3282
IS - 2
M1 - 2
ER -