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The risk of being depressed is significantly higher in cancer patients than in the general Population: Prevalence and severity of depressive symptoms across major cancer types

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The risk of being depressed is significantly higher in cancer patients than in the general Population: Prevalence and severity of depressive symptoms across major cancer types. / Hartung, T J; Brähler, E; Faller, H; Härter, M; Hinz, A; Johansen, C; Keller, M; Koch, U; Schulz, H; Weis, J; Mehnert, A.

in: EUR J CANCER, Jahrgang 72, 02.2017, S. 46-53.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Hartung, TJ, Brähler, E, Faller, H, Härter, M, Hinz, A, Johansen, C, Keller, M, Koch, U, Schulz, H, Weis, J & Mehnert, A 2017, 'The risk of being depressed is significantly higher in cancer patients than in the general Population: Prevalence and severity of depressive symptoms across major cancer types', EUR J CANCER, Jg. 72, S. 46-53. https://doi.org/10.1016/j.ejca.2016.11.017

APA

Hartung, T. J., Brähler, E., Faller, H., Härter, M., Hinz, A., Johansen, C., Keller, M., Koch, U., Schulz, H., Weis, J., & Mehnert, A. (2017). The risk of being depressed is significantly higher in cancer patients than in the general Population: Prevalence and severity of depressive symptoms across major cancer types. EUR J CANCER, 72, 46-53. https://doi.org/10.1016/j.ejca.2016.11.017

Vancouver

Hartung TJ, Brähler E, Faller H, Härter M, Hinz A, Johansen C et al. The risk of being depressed is significantly higher in cancer patients than in the general Population: Prevalence and severity of depressive symptoms across major cancer types. EUR J CANCER. 2017 Feb;72:46-53. https://doi.org/10.1016/j.ejca.2016.11.017

Bibtex

@article{69ea4b3f88304fc5bf0723eaf491fd7b,
title = "The risk of being depressed is significantly higher in cancer patients than in the general Population: Prevalence and severity of depressive symptoms across major cancer types",
abstract = "BACKGROUND: Depression is a common co-morbidity of cancer that has a detrimental effect on quality of life, treatment adherence and potentially survival. We conducted an epidemiological multi-center study including a population-based random comparison sample and estimated the prevalence of depressive symptoms by cancer site, thereby identifying cancer patients with the highest prevalence of depression.PATIENTS AND METHODS: We included 4020 adult cancer inpatients and outpatients from five distinct regions across Germany in a proportional stratified random sample based on the nationwide cancer incidence and a comparison group consisting of 5018 participants. Both groups reported depressive symptoms by filling in the Patient Health Questionnaire (PHQ-9). In multivariate analyses adjusted for age and sex, we calculated the odds of being depressed.RESULTS: Out of 5818 eligible patients, 69% participated (51% women, mean age = 58 years). We estimated that one in four cancer patients (24%) is depressed (PHQ-9 ≥ 10). The odds of being depressed among cancer patients were more than five times higher than in the general population (OR, 5.4; 95% CI, 4.6-6.2). Patients with pancreatic (M = 8.0, SD = 5.0), thyroid (M = 7.8, SD = 6.3) and brain tumours (M = 7.6, SD = 4.9) showed the highest prevalence, whereas patients with prostate cancer (M = 4.3, SD = 3.8) and malignant melanoma (M = 5.3, SD = 4.3) had the lowest levels of depressive symptoms.CONCLUSION: Our results help clinicians identify cancer patients in need of psychosocial support when navigating in the growing survivor population.",
keywords = "Adolescent, Adult, Aged, Depressive Disorder, Female, Germany, Humans, Male, Middle Aged, Multivariate Analysis, Neoplasms, Prevalence, Psychiatric Status Rating Scales, Young Adult, Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't",
author = "Hartung, {T J} and E Br{\"a}hler and H Faller and M H{\"a}rter and A Hinz and C Johansen and M Keller and U Koch and H Schulz and J Weis and A Mehnert",
note = "Copyright {\textcopyright} 2016 Elsevier Ltd. All rights reserved.",
year = "2017",
month = feb,
doi = "10.1016/j.ejca.2016.11.017",
language = "English",
volume = "72",
pages = "46--53",
journal = "EUR J CANCER",
issn = "0959-8049",
publisher = "Elsevier Limited",

}

RIS

TY - JOUR

T1 - The risk of being depressed is significantly higher in cancer patients than in the general Population: Prevalence and severity of depressive symptoms across major cancer types

AU - Hartung, T J

AU - Brähler, E

AU - Faller, H

AU - Härter, M

AU - Hinz, A

AU - Johansen, C

AU - Keller, M

AU - Koch, U

AU - Schulz, H

AU - Weis, J

AU - Mehnert, A

N1 - Copyright © 2016 Elsevier Ltd. All rights reserved.

PY - 2017/2

Y1 - 2017/2

N2 - BACKGROUND: Depression is a common co-morbidity of cancer that has a detrimental effect on quality of life, treatment adherence and potentially survival. We conducted an epidemiological multi-center study including a population-based random comparison sample and estimated the prevalence of depressive symptoms by cancer site, thereby identifying cancer patients with the highest prevalence of depression.PATIENTS AND METHODS: We included 4020 adult cancer inpatients and outpatients from five distinct regions across Germany in a proportional stratified random sample based on the nationwide cancer incidence and a comparison group consisting of 5018 participants. Both groups reported depressive symptoms by filling in the Patient Health Questionnaire (PHQ-9). In multivariate analyses adjusted for age and sex, we calculated the odds of being depressed.RESULTS: Out of 5818 eligible patients, 69% participated (51% women, mean age = 58 years). We estimated that one in four cancer patients (24%) is depressed (PHQ-9 ≥ 10). The odds of being depressed among cancer patients were more than five times higher than in the general population (OR, 5.4; 95% CI, 4.6-6.2). Patients with pancreatic (M = 8.0, SD = 5.0), thyroid (M = 7.8, SD = 6.3) and brain tumours (M = 7.6, SD = 4.9) showed the highest prevalence, whereas patients with prostate cancer (M = 4.3, SD = 3.8) and malignant melanoma (M = 5.3, SD = 4.3) had the lowest levels of depressive symptoms.CONCLUSION: Our results help clinicians identify cancer patients in need of psychosocial support when navigating in the growing survivor population.

AB - BACKGROUND: Depression is a common co-morbidity of cancer that has a detrimental effect on quality of life, treatment adherence and potentially survival. We conducted an epidemiological multi-center study including a population-based random comparison sample and estimated the prevalence of depressive symptoms by cancer site, thereby identifying cancer patients with the highest prevalence of depression.PATIENTS AND METHODS: We included 4020 adult cancer inpatients and outpatients from five distinct regions across Germany in a proportional stratified random sample based on the nationwide cancer incidence and a comparison group consisting of 5018 participants. Both groups reported depressive symptoms by filling in the Patient Health Questionnaire (PHQ-9). In multivariate analyses adjusted for age and sex, we calculated the odds of being depressed.RESULTS: Out of 5818 eligible patients, 69% participated (51% women, mean age = 58 years). We estimated that one in four cancer patients (24%) is depressed (PHQ-9 ≥ 10). The odds of being depressed among cancer patients were more than five times higher than in the general population (OR, 5.4; 95% CI, 4.6-6.2). Patients with pancreatic (M = 8.0, SD = 5.0), thyroid (M = 7.8, SD = 6.3) and brain tumours (M = 7.6, SD = 4.9) showed the highest prevalence, whereas patients with prostate cancer (M = 4.3, SD = 3.8) and malignant melanoma (M = 5.3, SD = 4.3) had the lowest levels of depressive symptoms.CONCLUSION: Our results help clinicians identify cancer patients in need of psychosocial support when navigating in the growing survivor population.

KW - Adolescent

KW - Adult

KW - Aged

KW - Depressive Disorder

KW - Female

KW - Germany

KW - Humans

KW - Male

KW - Middle Aged

KW - Multivariate Analysis

KW - Neoplasms

KW - Prevalence

KW - Psychiatric Status Rating Scales

KW - Young Adult

KW - Journal Article

KW - Multicenter Study

KW - Research Support, Non-U.S. Gov't

U2 - 10.1016/j.ejca.2016.11.017

DO - 10.1016/j.ejca.2016.11.017

M3 - SCORING: Journal article

C2 - 28024266

VL - 72

SP - 46

EP - 53

JO - EUR J CANCER

JF - EUR J CANCER

SN - 0959-8049

ER -