The relationship between global and specific components of quality of life, assessed with the EORTC QLQ-C30 in a sample of 2019 cancer patients
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The relationship between global and specific components of quality of life, assessed with the EORTC QLQ-C30 in a sample of 2019 cancer patients. / Hinz, A; Mehnert, A; Dégi, C; Reissmann, D R; Schotte, D; Schulte, T.
in: EUR J CANCER CARE, Jahrgang 26, Nr. 2, 03.2017, S. e12416.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - The relationship between global and specific components of quality of life, assessed with the EORTC QLQ-C30 in a sample of 2019 cancer patients
AU - Hinz, A
AU - Mehnert, A
AU - Dégi, C
AU - Reissmann, D R
AU - Schotte, D
AU - Schulte, T
N1 - © 2015 John Wiley & Sons Ltd.
PY - 2017/3
Y1 - 2017/3
N2 - Quality of life (QoL) is impaired in many cancer patients. The aim of this study was to test whether detriments in QoL were less pronounced in global assessments of QoL compared to more specific components. A total of 2059 cancer patients with mixed diagnoses were examined 6 months after discharge from a cancer rehabilitation clinic. QoL was measured with the EORTC QLQ-C30, which contains a global QoL scale, and 14 functioning and symptom scales and symptom items. A sample of the general population (n = 4476) served as controls. Regression analyses were performed to calculate expected mean scores for the patients, based on their age and gender distribution. Global QoL in the cancer sample (M = 69.3) was nearly equal to that of the general population, while the mean scores of all functioning scales, symptom scales and symptom items showed markedly worse QoL. This general relationship between global and specific QoL was found for seven of eight cancer types. The results indicate that global QoL is not the sum of its parts. This should be considered when treatment effects on QoL are examined. One alternative is to use higher order summarising functioning and symptom scales.
AB - Quality of life (QoL) is impaired in many cancer patients. The aim of this study was to test whether detriments in QoL were less pronounced in global assessments of QoL compared to more specific components. A total of 2059 cancer patients with mixed diagnoses were examined 6 months after discharge from a cancer rehabilitation clinic. QoL was measured with the EORTC QLQ-C30, which contains a global QoL scale, and 14 functioning and symptom scales and symptom items. A sample of the general population (n = 4476) served as controls. Regression analyses were performed to calculate expected mean scores for the patients, based on their age and gender distribution. Global QoL in the cancer sample (M = 69.3) was nearly equal to that of the general population, while the mean scores of all functioning scales, symptom scales and symptom items showed markedly worse QoL. This general relationship between global and specific QoL was found for seven of eight cancer types. The results indicate that global QoL is not the sum of its parts. This should be considered when treatment effects on QoL are examined. One alternative is to use higher order summarising functioning and symptom scales.
KW - Activities of Daily Living
KW - Adolescent
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Anorexia
KW - Antineoplastic Agents
KW - Cancer Pain
KW - Case-Control Studies
KW - Constipation
KW - Diarrhea
KW - Dyspnea
KW - Fatigue
KW - Female
KW - Germany
KW - Humans
KW - Male
KW - Middle Aged
KW - Nausea
KW - Neoplasms
KW - Quality of Life
KW - Radiotherapy
KW - Regression Analysis
KW - Sleep Initiation and Maintenance Disorders
KW - Surveys and Questionnaires
KW - Vomiting
KW - Young Adult
KW - Journal Article
U2 - 10.1111/ecc.12416
DO - 10.1111/ecc.12416
M3 - SCORING: Journal article
C2 - 26568527
VL - 26
SP - e12416
JO - EUR J CANCER CARE
JF - EUR J CANCER CARE
SN - 0961-5423
IS - 2
ER -
