The PVCR (posterior vertebral column resection) as a safe procedure for the treatment of unstable metastases with extensive epidural tumor growth
Beteiligte Einrichtungen
Abstract
Results: 79 patients were included. The mean follow-up was 524±762 days. At the time of the operation, the age was 64.9±10.5 years. The most common underlying diseases were multiple myelomas (n = 22), breast cancer (n = 16), and lung cancer (n = 11). The SINS was 11.6±2.4. The Epidural Spinal Cord Compression Score (ESCC) was 2.7±0.5. The NRS (pre- 6.1±1.7 vs. postop 3.3±1.6) and segmental kyphosis (pre- 13.8 °±8.4 ° vs. postop 3.8 °±5.5 °) decreased significantly (p <0.001). The Frankel score worsened postoperatively in two (3%) patients, while an improvement was documented in 14 (18%) patients. The KPS remained constant during the observation period (preoperatively 73.0±18.4% vs. follow-up 78.4±18.2%). Bony fusion was observed in 32 of 37 (86.5%) patients who received CT imaging more than 100 days after index surgery.
Conclusion: This study shows, that pVCR is a reliable surgical technique in patients with epidural tumor compression and concomitant instability. It could be shown that the NRS was reduced in the short- and mid-term outcome, the KPS could be kept stable despite the seriously ill patients. The improvement in the Frankel score shows that the surgical objective can be reliably achieved. Despite the postoperative radiation, fusion rates of 86% could be observed. We conclude that pVCR is a safe, fast and efficient strategy to achieve stability and pain relief in the long term in patients with epidural tumor compression.
Bibliografische Daten
Originalsprache | Englisch |
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Aufsatznummer | 101079 |
ISSN | 2772-5294 |
DOIs | |
Status | Veröffentlicht - 13.10.2023 |