The memory trace of a stressful episode

Anne Bierbrauer; Marie-Christin Fellner; Rebekka Heinen; Oliver T Wolf; Nikolai Axmacher

doi:10.1016/j.cub.2021.09.044

The memory trace of a stressful episode

Standard

The memory trace of a stressful episode. / Bierbrauer, Anne; Fellner, Marie-Christin; Heinen, Rebekka; Wolf, Oliver T; Axmacher, Nikolai.

in: CURR BIOL, Jahrgang 31, Nr. 23, 06.12.2021, S. 5204-5213.e8.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Bierbrauer, A, Fellner, M-C, Heinen, R, Wolf, OT & Axmacher, N 2021, 'The memory trace of a stressful episode', CURR BIOL, Jg. 31, Nr. 23, S. 5204-5213.e8. https://doi.org/10.1016/j.cub.2021.09.044

APA

Bierbrauer, A., Fellner, M-C., Heinen, R., Wolf, O. T., & Axmacher, N. (2021). The memory trace of a stressful episode. CURR BIOL, 31(23), 5204-5213.e8. https://doi.org/10.1016/j.cub.2021.09.044

Vancouver

Bierbrauer A, Fellner M-C, Heinen R, Wolf OT, Axmacher N. The memory trace of a stressful episode. CURR BIOL. 2021 Dez 6;31(23):5204-5213.e8. https://doi.org/10.1016/j.cub.2021.09.044

Bibtex

@article{0e2fc3f4675648f4b877baea46ff71f1,

title = "The memory trace of a stressful episode",

abstract = "Stress influences episodic memory formation via noradrenaline and glucocorticoid effects on amygdala and hippocampus. A common finding is the improvement of memory for central aspects of a stressful episode. This is putatively related to changes in the neural representations of specific experiences, i.e., their memory traces. Here we show that the memory improvement for objects that were encountered in a stressful episode relates to differences in the neural representations of these objects in the amygdala. Using functional magnetic resonance imaging, we found that stress specifically altered the representations of central objects: compared to control objects, they became more similar to one another and more distinct from objects that were not part of this episode. Furthermore, higher similarity of central objects to the main stressor-the faces of the stress-inducing committee members-predicted better memory. This suggests that the central objects were closely integrated into a stressor-centered memory representation. Our findings provide mechanistic insights into how stress shapes the memory trace and have profound implications for neurocognitive models of stressful and emotional memory.",

keywords = "Amygdala, Emotions, Hippocampus, Magnetic Resonance Imaging, Memory, Episodic",

author = "Anne Bierbrauer and Marie-Christin Fellner and Rebekka Heinen and Wolf, {Oliver T} and Nikolai Axmacher",

year = "2021",

month = dec,

day = "6",

doi = "10.1016/j.cub.2021.09.044",

language = "English",

volume = "31",

pages = "5204--5213.e8",

journal = "CURR BIOL",

issn = "0960-9822",

publisher = "Cell Press",

number = "23",

}

RIS

TY - JOUR

T1 - The memory trace of a stressful episode

AU - Bierbrauer, Anne

AU - Fellner, Marie-Christin

AU - Heinen, Rebekka

AU - Wolf, Oliver T

AU - Axmacher, Nikolai

PY - 2021/12/6

Y1 - 2021/12/6

N2 - Stress influences episodic memory formation via noradrenaline and glucocorticoid effects on amygdala and hippocampus. A common finding is the improvement of memory for central aspects of a stressful episode. This is putatively related to changes in the neural representations of specific experiences, i.e., their memory traces. Here we show that the memory improvement for objects that were encountered in a stressful episode relates to differences in the neural representations of these objects in the amygdala. Using functional magnetic resonance imaging, we found that stress specifically altered the representations of central objects: compared to control objects, they became more similar to one another and more distinct from objects that were not part of this episode. Furthermore, higher similarity of central objects to the main stressor-the faces of the stress-inducing committee members-predicted better memory. This suggests that the central objects were closely integrated into a stressor-centered memory representation. Our findings provide mechanistic insights into how stress shapes the memory trace and have profound implications for neurocognitive models of stressful and emotional memory.

AB - Stress influences episodic memory formation via noradrenaline and glucocorticoid effects on amygdala and hippocampus. A common finding is the improvement of memory for central aspects of a stressful episode. This is putatively related to changes in the neural representations of specific experiences, i.e., their memory traces. Here we show that the memory improvement for objects that were encountered in a stressful episode relates to differences in the neural representations of these objects in the amygdala. Using functional magnetic resonance imaging, we found that stress specifically altered the representations of central objects: compared to control objects, they became more similar to one another and more distinct from objects that were not part of this episode. Furthermore, higher similarity of central objects to the main stressor-the faces of the stress-inducing committee members-predicted better memory. This suggests that the central objects were closely integrated into a stressor-centered memory representation. Our findings provide mechanistic insights into how stress shapes the memory trace and have profound implications for neurocognitive models of stressful and emotional memory.

KW - Amygdala

KW - Emotions

KW - Hippocampus

KW - Magnetic Resonance Imaging

KW - Memory, Episodic

U2 - 10.1016/j.cub.2021.09.044

DO - 10.1016/j.cub.2021.09.044

M3 - SCORING: Journal article

C2 - 34653359

VL - 31

SP - 5204-5213.e8

JO - CURR BIOL

JF - CURR BIOL

SN - 0960-9822

IS - 23

ER -