The long-term impact of in vitro drug sensitivity on risk stratification and treatment outcome in acute lymphoblastic leukemia of childhood (CoALL 06-97).

Gabriele Escherich; Anja F Troeger; Ulrich Gobel; Ulrike Graubner; Arnulf Pekrun; Norbert Jorch; Gjl Kaspers; Martin Zimmermann; Udo Zur Stadt; Karin Kazemir; Rob Pieters; Martin Horstmann; Monique L Denboer; Gritta Janka-Schaub

doi:10.3324/haematol.2010.039735

The long-term impact of in vitro drug sensitivity on risk stratification and treatment outcome in acute lymphoblastic leukemia of childhood (CoALL 06-97).

Standard

The long-term impact of in vitro drug sensitivity on risk stratification and treatment outcome in acute lymphoblastic leukemia of childhood (CoALL 06-97). / Escherich, Gabriele; Troeger, Anja F; Gobel, Ulrich; Graubner, Ulrike; Pekrun, Arnulf; Jorch, Norbert; Kaspers, Gjl; Zimmermann, Martin; Zur Stadt, Udo; Kazemir, Karin; Pieters, Rob; Horstmann, Martin; Denboer, Monique L; Janka-Schaub, Gritta.

in: HAEMATOLOGICA, Jahrgang 96, Nr. 6, 6, 2011, S. 854-862.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Escherich, G, Troeger, AF, Gobel, U, Graubner, U, Pekrun, A, Jorch, N, Kaspers, G, Zimmermann, M, Zur Stadt, U, Kazemir, K, Pieters, R, Horstmann, M, Denboer, ML & Janka-Schaub, G 2011, 'The long-term impact of in vitro drug sensitivity on risk stratification and treatment outcome in acute lymphoblastic leukemia of childhood (CoALL 06-97).', HAEMATOLOGICA, Jg. 96, Nr. 6, 6, S. 854-862. https://doi.org/10.3324/haematol.2010.039735

APA

Escherich, G., Troeger, A. F., Gobel, U., Graubner, U., Pekrun, A., Jorch, N., Kaspers, G., Zimmermann, M., Zur Stadt, U., Kazemir, K., Pieters, R., Horstmann, M., Denboer, M. L., & Janka-Schaub, G. (2011). The long-term impact of in vitro drug sensitivity on risk stratification and treatment outcome in acute lymphoblastic leukemia of childhood (CoALL 06-97). HAEMATOLOGICA, 96(6), 854-862. [6]. https://doi.org/10.3324/haematol.2010.039735

Vancouver

Escherich G, Troeger AF, Gobel U, Graubner U, Pekrun A, Jorch N et al. The long-term impact of in vitro drug sensitivity on risk stratification and treatment outcome in acute lymphoblastic leukemia of childhood (CoALL 06-97). HAEMATOLOGICA. 2011;96(6):854-862. 6. https://doi.org/10.3324/haematol.2010.039735

Bibtex

@article{73d089085bdc414d9066590feee8b9ce,

title = "The long-term impact of in vitro drug sensitivity on risk stratification and treatment outcome in acute lymphoblastic leukemia of childhood (CoALL 06-97).",

abstract = "In a study of childhood acute lymphoblastic leukemia (CoALL 06-97 study), the in vitro sensitivity of the patients' cells to prednisolone, vincristine and asparaginase was introduced as a new additional risk parameter for treatment stratification. In parallel in vivo treatment response was assessed by determining the presence and extent of minimal residual disease in a subset of patients (n=224). Here we report the long-term impact of in vitro sensitivity-based risk stratification according to survival and compare the results of in vitro sensitivity with in vivo response.",

author = "Gabriele Escherich and Troeger, {Anja F} and Ulrich Gobel and Ulrike Graubner and Arnulf Pekrun and Norbert Jorch and Gjl Kaspers and Martin Zimmermann and {Zur Stadt}, Udo and Karin Kazemir and Rob Pieters and Martin Horstmann and Denboer, {Monique L} and Gritta Janka-Schaub",

year = "2011",

doi = "10.3324/haematol.2010.039735",

language = "English",

volume = "96",

pages = "854--862",

journal = "HAEMATOLOGICA",

issn = "0390-6078",

publisher = "Ferrata Storti Foundation",

number = "6",

}

RIS

TY - JOUR

T1 - The long-term impact of in vitro drug sensitivity on risk stratification and treatment outcome in acute lymphoblastic leukemia of childhood (CoALL 06-97).

AU - Escherich, Gabriele

AU - Troeger, Anja F

AU - Gobel, Ulrich

AU - Graubner, Ulrike

AU - Pekrun, Arnulf

AU - Jorch, Norbert

AU - Kaspers, Gjl

AU - Zimmermann, Martin

AU - Zur Stadt, Udo

AU - Kazemir, Karin

AU - Pieters, Rob

AU - Horstmann, Martin

AU - Denboer, Monique L

AU - Janka-Schaub, Gritta

PY - 2011

Y1 - 2011

N2 - In a study of childhood acute lymphoblastic leukemia (CoALL 06-97 study), the in vitro sensitivity of the patients' cells to prednisolone, vincristine and asparaginase was introduced as a new additional risk parameter for treatment stratification. In parallel in vivo treatment response was assessed by determining the presence and extent of minimal residual disease in a subset of patients (n=224). Here we report the long-term impact of in vitro sensitivity-based risk stratification according to survival and compare the results of in vitro sensitivity with in vivo response.

AB - In a study of childhood acute lymphoblastic leukemia (CoALL 06-97 study), the in vitro sensitivity of the patients' cells to prednisolone, vincristine and asparaginase was introduced as a new additional risk parameter for treatment stratification. In parallel in vivo treatment response was assessed by determining the presence and extent of minimal residual disease in a subset of patients (n=224). Here we report the long-term impact of in vitro sensitivity-based risk stratification according to survival and compare the results of in vitro sensitivity with in vivo response.

U2 - 10.3324/haematol.2010.039735

DO - 10.3324/haematol.2010.039735

M3 - SCORING: Journal article

VL - 96

SP - 854

EP - 862

JO - HAEMATOLOGICA

JF - HAEMATOLOGICA

SN - 0390-6078

IS - 6

M1 - 6

ER -