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The impact of Enhanced Recovery after Surgery (ERAS) pathways with regard to perioperative outcome in patients with ovarian cancer

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The impact of Enhanced Recovery after Surgery (ERAS) pathways with regard to perioperative outcome in patients with ovarian cancer. / Reuter, Susanne; Woelber, Linn; Trepte, Constantin C; Perez, Daniel; Zapf, Antonia; Cevirme, Sinan; Mueller, Volkmar; Schmalfeldt, Barbara; Jaeger, Anna.

in: ARCH GYNECOL OBSTET, Jahrgang 306, Nr. 1, 07.2022, S. 199-207.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Reuter, S, Woelber, L, Trepte, CC, Perez, D, Zapf, A, Cevirme, S, Mueller, V, Schmalfeldt, B & Jaeger, A 2022, 'The impact of Enhanced Recovery after Surgery (ERAS) pathways with regard to perioperative outcome in patients with ovarian cancer', ARCH GYNECOL OBSTET, Jg. 306, Nr. 1, S. 199-207. https://doi.org/10.1007/s00404-021-06339-6

APA

Reuter, S., Woelber, L., Trepte, C. C., Perez, D., Zapf, A., Cevirme, S., Mueller, V., Schmalfeldt, B., & Jaeger, A. (2022). The impact of Enhanced Recovery after Surgery (ERAS) pathways with regard to perioperative outcome in patients with ovarian cancer. ARCH GYNECOL OBSTET, 306(1), 199-207. https://doi.org/10.1007/s00404-021-06339-6

Vancouver

Reuter S, Woelber L, Trepte CC, Perez D, Zapf A, Cevirme S et al. The impact of Enhanced Recovery after Surgery (ERAS) pathways with regard to perioperative outcome in patients with ovarian cancer. ARCH GYNECOL OBSTET. 2022 Jul;306(1):199-207. https://doi.org/10.1007/s00404-021-06339-6

Bibtex

@article{90b17afdfc034c50b11c3ae5b46f4ac7,
title = "The impact of Enhanced Recovery after Surgery (ERAS) pathways with regard to perioperative outcome in patients with ovarian cancer",
abstract = "PURPOSE: Major surgery for ovarian cancer is associated with significant morbidity. Recently, guidelines for perioperative care in gynecologic oncology with a structured {"}Enhanced Recovery after Surgery (ERAS){"} program were presented. Our aim was to evaluate if implementation of ERAS reduces postoperative complications in patients undergoing extensive cytoreductive surgery for ovarian cancer.METHODS: 134 patients with ovarian cancer (FIGO I-IV) were included. 47 patients were prospectively studied after implementation of a mandatory ERAS protocol (ERAS group) and compared to 87 patients that were treated before implementation (pre-ERAS group). Primary endpoints of this study were the effects of the ERAS protocol on postoperative complications and length of stay in hospital.RESULTS: Preoperative and surgical data were comparable in both groups. Only the POSSUM score was higher in the ERAS group (11.8% vs. 9.3%, p < 0.001), indicating a higher surgical risk in the ERAS group. Total number of postoperative complications (ERAS: 29.8% vs. pre-ERAS: 52.8%, p = 0.011), and length of hospital stay (ERAS: 11 (6-23) vs pre-ERAS: 13 (6-50) days; p < 0.001) differed significantly. A lower fraction of patients of the ERAS group (87.2%) needed postoperative admission to the ICU compared to the pre-ERAS group (97.7%), p = 0.022). Mortality within the ERAS group was 0% vs. 3.4% (p = 0.552) in the pre-ERAS group.CONCLUSION: The implementation of a mandatory ERAS protocol was associated with a lower rate of postoperative complications and a reduced length of stay in hospital. If ERAS has influence on long-term outcome needs to be further evaluated.",
author = "Susanne Reuter and Linn Woelber and Trepte, {Constantin C} and Daniel Perez and Antonia Zapf and Sinan Cevirme and Volkmar Mueller and Barbara Schmalfeldt and Anna Jaeger",
note = "{\textcopyright} 2021. The Author(s).",
year = "2022",
month = jul,
doi = "10.1007/s00404-021-06339-6",
language = "English",
volume = "306",
pages = "199--207",
journal = "ARCH GYNECOL OBSTET",
issn = "0932-0067",
publisher = "Springer",
number = "1",

}

RIS

TY - JOUR

T1 - The impact of Enhanced Recovery after Surgery (ERAS) pathways with regard to perioperative outcome in patients with ovarian cancer

AU - Reuter, Susanne

AU - Woelber, Linn

AU - Trepte, Constantin C

AU - Perez, Daniel

AU - Zapf, Antonia

AU - Cevirme, Sinan

AU - Mueller, Volkmar

AU - Schmalfeldt, Barbara

AU - Jaeger, Anna

N1 - © 2021. The Author(s).

PY - 2022/7

Y1 - 2022/7

N2 - PURPOSE: Major surgery for ovarian cancer is associated with significant morbidity. Recently, guidelines for perioperative care in gynecologic oncology with a structured "Enhanced Recovery after Surgery (ERAS)" program were presented. Our aim was to evaluate if implementation of ERAS reduces postoperative complications in patients undergoing extensive cytoreductive surgery for ovarian cancer.METHODS: 134 patients with ovarian cancer (FIGO I-IV) were included. 47 patients were prospectively studied after implementation of a mandatory ERAS protocol (ERAS group) and compared to 87 patients that were treated before implementation (pre-ERAS group). Primary endpoints of this study were the effects of the ERAS protocol on postoperative complications and length of stay in hospital.RESULTS: Preoperative and surgical data were comparable in both groups. Only the POSSUM score was higher in the ERAS group (11.8% vs. 9.3%, p < 0.001), indicating a higher surgical risk in the ERAS group. Total number of postoperative complications (ERAS: 29.8% vs. pre-ERAS: 52.8%, p = 0.011), and length of hospital stay (ERAS: 11 (6-23) vs pre-ERAS: 13 (6-50) days; p < 0.001) differed significantly. A lower fraction of patients of the ERAS group (87.2%) needed postoperative admission to the ICU compared to the pre-ERAS group (97.7%), p = 0.022). Mortality within the ERAS group was 0% vs. 3.4% (p = 0.552) in the pre-ERAS group.CONCLUSION: The implementation of a mandatory ERAS protocol was associated with a lower rate of postoperative complications and a reduced length of stay in hospital. If ERAS has influence on long-term outcome needs to be further evaluated.

AB - PURPOSE: Major surgery for ovarian cancer is associated with significant morbidity. Recently, guidelines for perioperative care in gynecologic oncology with a structured "Enhanced Recovery after Surgery (ERAS)" program were presented. Our aim was to evaluate if implementation of ERAS reduces postoperative complications in patients undergoing extensive cytoreductive surgery for ovarian cancer.METHODS: 134 patients with ovarian cancer (FIGO I-IV) were included. 47 patients were prospectively studied after implementation of a mandatory ERAS protocol (ERAS group) and compared to 87 patients that were treated before implementation (pre-ERAS group). Primary endpoints of this study were the effects of the ERAS protocol on postoperative complications and length of stay in hospital.RESULTS: Preoperative and surgical data were comparable in both groups. Only the POSSUM score was higher in the ERAS group (11.8% vs. 9.3%, p < 0.001), indicating a higher surgical risk in the ERAS group. Total number of postoperative complications (ERAS: 29.8% vs. pre-ERAS: 52.8%, p = 0.011), and length of hospital stay (ERAS: 11 (6-23) vs pre-ERAS: 13 (6-50) days; p < 0.001) differed significantly. A lower fraction of patients of the ERAS group (87.2%) needed postoperative admission to the ICU compared to the pre-ERAS group (97.7%), p = 0.022). Mortality within the ERAS group was 0% vs. 3.4% (p = 0.552) in the pre-ERAS group.CONCLUSION: The implementation of a mandatory ERAS protocol was associated with a lower rate of postoperative complications and a reduced length of stay in hospital. If ERAS has influence on long-term outcome needs to be further evaluated.

U2 - 10.1007/s00404-021-06339-6

DO - 10.1007/s00404-021-06339-6

M3 - SCORING: Journal article

C2 - 34958401

VL - 306

SP - 199

EP - 207

JO - ARCH GYNECOL OBSTET

JF - ARCH GYNECOL OBSTET

SN - 0932-0067

IS - 1

ER -