The functional anatomy of Gilles de la Tourette syndrome

Christos Ganos; Veit Roessner; Alexander Münchau

doi:10.1016/j.neubiorev.2012.11.004

The functional anatomy of Gilles de la Tourette syndrome

Standard

The functional anatomy of Gilles de la Tourette syndrome. / Ganos, Christos; Roessner, Veit; Münchau, Alexander.

in: NEUROSCI BIOBEHAV R, Jahrgang 37, Nr. 6, 07.2013, S. 1050-62.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Ganos, C, Roessner, V & Münchau, A 2013, 'The functional anatomy of Gilles de la Tourette syndrome', NEUROSCI BIOBEHAV R, Jg. 37, Nr. 6, S. 1050-62. https://doi.org/10.1016/j.neubiorev.2012.11.004

APA

Ganos, C., Roessner, V., & Münchau, A. (2013). The functional anatomy of Gilles de la Tourette syndrome. NEUROSCI BIOBEHAV R, 37(6), 1050-62. https://doi.org/10.1016/j.neubiorev.2012.11.004

Vancouver

Ganos C, Roessner V, Münchau A. The functional anatomy of Gilles de la Tourette syndrome. NEUROSCI BIOBEHAV R. 2013 Jul;37(6):1050-62. https://doi.org/10.1016/j.neubiorev.2012.11.004

Bibtex

@article{00a25bde3d2449fc8426543b5e96797b,

title = "The functional anatomy of Gilles de la Tourette syndrome",

abstract = "Gilles de la Tourette syndrome (GTS) holds a prime position as a disorder transgressing the brittle boundaries of neurology and psychiatry with an entangling web of motor and behavioral problems. With tics as the disorder's hallmark and myriads of related signs such as echo-, pali- and coprophenomena, paralleled by a broad neuropsychiatric spectrum of comorbidities encompassing attention deficit hyperactivity disorder, obsessive-compulsive disorder and self-injurious behavior and depression, GTS pathophysiology remains enigmatic. In this review, in the light of GTS phenomenology, we will focus on current theories of tic-emergence related to aberrant activity in the basal ganglia and abnormal basal ganglia-cortex interplay through cortico-striato-thalamocortical loops from an anatomical, neurophysiological and functional-neuroimaging perspective. We will attempt a holistic view to the countless major and minor drawbacks of the GTS brain and comment on future directions of neuroscientific research to elucidate this common and complex neuropsychiatric syndrome, which merits scientific understanding and social acceptance.",

keywords = "Brain, Humans, Movement Disorders, Neural Pathways, Neuroimaging, Tics, Tourette Syndrome",

author = "Christos Ganos and Veit Roessner and Alexander M{\"u}nchau",

year = "2013",

month = jul,

doi = "10.1016/j.neubiorev.2012.11.004",

language = "English",

volume = "37",

pages = "1050--62",

journal = "NEUROSCI BIOBEHAV R",

issn = "0149-7634",

publisher = "Elsevier Limited",

number = "6",

}

RIS

TY - JOUR

T1 - The functional anatomy of Gilles de la Tourette syndrome

AU - Ganos, Christos

AU - Roessner, Veit

AU - Münchau, Alexander

PY - 2013/7

Y1 - 2013/7

N2 - Gilles de la Tourette syndrome (GTS) holds a prime position as a disorder transgressing the brittle boundaries of neurology and psychiatry with an entangling web of motor and behavioral problems. With tics as the disorder's hallmark and myriads of related signs such as echo-, pali- and coprophenomena, paralleled by a broad neuropsychiatric spectrum of comorbidities encompassing attention deficit hyperactivity disorder, obsessive-compulsive disorder and self-injurious behavior and depression, GTS pathophysiology remains enigmatic. In this review, in the light of GTS phenomenology, we will focus on current theories of tic-emergence related to aberrant activity in the basal ganglia and abnormal basal ganglia-cortex interplay through cortico-striato-thalamocortical loops from an anatomical, neurophysiological and functional-neuroimaging perspective. We will attempt a holistic view to the countless major and minor drawbacks of the GTS brain and comment on future directions of neuroscientific research to elucidate this common and complex neuropsychiatric syndrome, which merits scientific understanding and social acceptance.

AB - Gilles de la Tourette syndrome (GTS) holds a prime position as a disorder transgressing the brittle boundaries of neurology and psychiatry with an entangling web of motor and behavioral problems. With tics as the disorder's hallmark and myriads of related signs such as echo-, pali- and coprophenomena, paralleled by a broad neuropsychiatric spectrum of comorbidities encompassing attention deficit hyperactivity disorder, obsessive-compulsive disorder and self-injurious behavior and depression, GTS pathophysiology remains enigmatic. In this review, in the light of GTS phenomenology, we will focus on current theories of tic-emergence related to aberrant activity in the basal ganglia and abnormal basal ganglia-cortex interplay through cortico-striato-thalamocortical loops from an anatomical, neurophysiological and functional-neuroimaging perspective. We will attempt a holistic view to the countless major and minor drawbacks of the GTS brain and comment on future directions of neuroscientific research to elucidate this common and complex neuropsychiatric syndrome, which merits scientific understanding and social acceptance.

KW - Brain

KW - Humans

KW - Movement Disorders

KW - Neural Pathways

KW - Neuroimaging

KW - Tics

KW - Tourette Syndrome

U2 - 10.1016/j.neubiorev.2012.11.004

DO - 10.1016/j.neubiorev.2012.11.004

M3 - SCORING: Journal article

C2 - 23237884

VL - 37

SP - 1050

EP - 1062

JO - NEUROSCI BIOBEHAV R

JF - NEUROSCI BIOBEHAV R

SN - 0149-7634

IS - 6

ER -