The Fire Within: Microbes Inflame Tumors
Standard
The Fire Within: Microbes Inflame Tumors. / Gagliani, Nicola; Hu, Bo; Huber, Samuel; Elinav, Eran; Flavell, Richard A.
in: CELL, Jahrgang 157, Nr. 4, 08.05.2014, S. 776-783.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - The Fire Within: Microbes Inflame Tumors
AU - Gagliani, Nicola
AU - Hu, Bo
AU - Huber, Samuel
AU - Elinav, Eran
AU - Flavell, Richard A
N1 - Copyright © 2014 Elsevier Inc. All rights reserved.
PY - 2014/5/8
Y1 - 2014/5/8
N2 - The immune system and the microbiota mutually interact to maintain homeostasis in the intestine. However, components of the microbiota can alter this balance and promote chronic inflammation, promoting intestinal tumor development. We review recent advances in understanding the complex interactions between the microbiota and the innate and adaptive immune systems and discuss their potential to lead us in new directions for understanding cancer biology and treatment.
AB - The immune system and the microbiota mutually interact to maintain homeostasis in the intestine. However, components of the microbiota can alter this balance and promote chronic inflammation, promoting intestinal tumor development. We review recent advances in understanding the complex interactions between the microbiota and the innate and adaptive immune systems and discuss their potential to lead us in new directions for understanding cancer biology and treatment.
U2 - 10.1016/j.cell.2014.03.006
DO - 10.1016/j.cell.2014.03.006
M3 - SCORING: Journal article
C2 - 24813605
VL - 157
SP - 776
EP - 783
JO - CELL
JF - CELL
SN - 0092-8674
IS - 4
ER -