The ether-à-go-go-Related Gene K(+) Current: Functions of a Strange Inward Rectifier

  • Jürgen R Schwarz
  • Christiane K. Bauer

Abstract

The erg channels mediate an inward-rectifying K(+) current because of their peculiar gating kinetics. They are involved in repolarization of the cardiac action potential, frequency adaptation, and maintenance of the resting potential. Reduction of erg currents via an intracellular signal cascade underlies the thyrotropin-releasing hormone-induced increase in prolactin secretion.

Bibliografische Daten

OriginalspracheEnglisch
ISSN0886-1714
DOIs
StatusVeröffentlicht - 1999
pubmed 11390839