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The effects of transjugular intrahepatic portosystemic stent shunt on systemic cardiocirculatory parameters

Standard

The effects of transjugular intrahepatic portosystemic stent shunt on systemic cardiocirculatory parameters. / Saugel, Bernd; Mair, Sebastian; Meidert, Agnes S; Phillip, Veit; Messer, Marlena; Nennstiel, Simon; Berger, Hermann; Gaa, Jochen; Wagner, Julia Y; Schneider, Heike; Schmid, Roland M; Huber, Wolfgang.

in: J CRIT CARE, Jahrgang 29, Nr. 6, 16.08.2014, S. 1001-1005.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Saugel, B, Mair, S, Meidert, AS, Phillip, V, Messer, M, Nennstiel, S, Berger, H, Gaa, J, Wagner, JY, Schneider, H, Schmid, RM & Huber, W 2014, 'The effects of transjugular intrahepatic portosystemic stent shunt on systemic cardiocirculatory parameters', J CRIT CARE, Jg. 29, Nr. 6, S. 1001-1005. https://doi.org/10.1016/j.jcrc.2014.06.028

APA

Saugel, B., Mair, S., Meidert, A. S., Phillip, V., Messer, M., Nennstiel, S., Berger, H., Gaa, J., Wagner, J. Y., Schneider, H., Schmid, R. M., & Huber, W. (2014). The effects of transjugular intrahepatic portosystemic stent shunt on systemic cardiocirculatory parameters. J CRIT CARE, 29(6), 1001-1005. https://doi.org/10.1016/j.jcrc.2014.06.028

Vancouver

Saugel B, Mair S, Meidert AS, Phillip V, Messer M, Nennstiel S et al. The effects of transjugular intrahepatic portosystemic stent shunt on systemic cardiocirculatory parameters. J CRIT CARE. 2014 Aug 16;29(6):1001-1005. https://doi.org/10.1016/j.jcrc.2014.06.028

Bibtex

@article{08bc8538d922422ca6730787fbc14797,
title = "The effects of transjugular intrahepatic portosystemic stent shunt on systemic cardiocirculatory parameters",
abstract = "PURPOSE: We aimed to evaluate the effects of transjugular intrahepatic portosystemic stent shunt (TIPS) on systemic cardiocirculatory parameters in patients treated with TIPS for portal hypertension-associated complications.MATERIALS AND METHODS: This prospective study was conducted in an intensive care unit of a German university hospital (October 2010-July 2013). We assessed hemodynamic parameters before and after TIPS placement using single-indicator transpulmonary thermodilution and pulse contour analysis. After exclusion of 5 patients treated with vasoactive agents during study measurements, 15 patients were included in the final statistical analysis.RESULTS: Transjugular intrahepatic portosystemic stent shunt induced a statistically significant decrease in portal pressure (median, 29 [25%-75% percentile range, 23-37] mm Hg before TIPS vs 21 [18-27] mm Hg after TIPS; P < .01) in parallel with a statistically significant increase in central venous pressure (10 [6-15] mm Hg before TIPS vs 13 [9-16] mm Hg after TIPS; P = .01), cardiac index (3.8 [2.9-4.6] L min(-1) m(-2) before TIPS vs 4.5 [3.8-5.4] L min(-1) m(-2) 14 hours after TIPS; P = .01), and stroke volume index (54 [42-60] mL/m(2) before TIPS vs 60 [47-63] mL/m(2) 14 hours after TIPS; P = .03). Arterial blood pressure and systemic vascular resistance index were statistically significantly lower after TIPS.CONCLUSIONS: Transjugular intrahepatic portosystemic stent shunt placement is associated with an increase in central venous pressure and an improvement of global blood flow (cardiac index and stroke volume index) in patients with portal hypertension.",
author = "Bernd Saugel and Sebastian Mair and Meidert, {Agnes S} and Veit Phillip and Marlena Messer and Simon Nennstiel and Hermann Berger and Jochen Gaa and Wagner, {Julia Y} and Heike Schneider and Schmid, {Roland M} and Wolfgang Huber",
note = "Copyright {\textcopyright} 2014 Elsevier Inc. All rights reserved.",
year = "2014",
month = aug,
day = "16",
doi = "10.1016/j.jcrc.2014.06.028",
language = "English",
volume = "29",
pages = "1001--1005",
journal = "J CRIT CARE",
issn = "0883-9441",
publisher = "Elsevier BV",
number = "6",

}

RIS

TY - JOUR

T1 - The effects of transjugular intrahepatic portosystemic stent shunt on systemic cardiocirculatory parameters

AU - Saugel, Bernd

AU - Mair, Sebastian

AU - Meidert, Agnes S

AU - Phillip, Veit

AU - Messer, Marlena

AU - Nennstiel, Simon

AU - Berger, Hermann

AU - Gaa, Jochen

AU - Wagner, Julia Y

AU - Schneider, Heike

AU - Schmid, Roland M

AU - Huber, Wolfgang

N1 - Copyright © 2014 Elsevier Inc. All rights reserved.

PY - 2014/8/16

Y1 - 2014/8/16

N2 - PURPOSE: We aimed to evaluate the effects of transjugular intrahepatic portosystemic stent shunt (TIPS) on systemic cardiocirculatory parameters in patients treated with TIPS for portal hypertension-associated complications.MATERIALS AND METHODS: This prospective study was conducted in an intensive care unit of a German university hospital (October 2010-July 2013). We assessed hemodynamic parameters before and after TIPS placement using single-indicator transpulmonary thermodilution and pulse contour analysis. After exclusion of 5 patients treated with vasoactive agents during study measurements, 15 patients were included in the final statistical analysis.RESULTS: Transjugular intrahepatic portosystemic stent shunt induced a statistically significant decrease in portal pressure (median, 29 [25%-75% percentile range, 23-37] mm Hg before TIPS vs 21 [18-27] mm Hg after TIPS; P < .01) in parallel with a statistically significant increase in central venous pressure (10 [6-15] mm Hg before TIPS vs 13 [9-16] mm Hg after TIPS; P = .01), cardiac index (3.8 [2.9-4.6] L min(-1) m(-2) before TIPS vs 4.5 [3.8-5.4] L min(-1) m(-2) 14 hours after TIPS; P = .01), and stroke volume index (54 [42-60] mL/m(2) before TIPS vs 60 [47-63] mL/m(2) 14 hours after TIPS; P = .03). Arterial blood pressure and systemic vascular resistance index were statistically significantly lower after TIPS.CONCLUSIONS: Transjugular intrahepatic portosystemic stent shunt placement is associated with an increase in central venous pressure and an improvement of global blood flow (cardiac index and stroke volume index) in patients with portal hypertension.

AB - PURPOSE: We aimed to evaluate the effects of transjugular intrahepatic portosystemic stent shunt (TIPS) on systemic cardiocirculatory parameters in patients treated with TIPS for portal hypertension-associated complications.MATERIALS AND METHODS: This prospective study was conducted in an intensive care unit of a German university hospital (October 2010-July 2013). We assessed hemodynamic parameters before and after TIPS placement using single-indicator transpulmonary thermodilution and pulse contour analysis. After exclusion of 5 patients treated with vasoactive agents during study measurements, 15 patients were included in the final statistical analysis.RESULTS: Transjugular intrahepatic portosystemic stent shunt induced a statistically significant decrease in portal pressure (median, 29 [25%-75% percentile range, 23-37] mm Hg before TIPS vs 21 [18-27] mm Hg after TIPS; P < .01) in parallel with a statistically significant increase in central venous pressure (10 [6-15] mm Hg before TIPS vs 13 [9-16] mm Hg after TIPS; P = .01), cardiac index (3.8 [2.9-4.6] L min(-1) m(-2) before TIPS vs 4.5 [3.8-5.4] L min(-1) m(-2) 14 hours after TIPS; P = .01), and stroke volume index (54 [42-60] mL/m(2) before TIPS vs 60 [47-63] mL/m(2) 14 hours after TIPS; P = .03). Arterial blood pressure and systemic vascular resistance index were statistically significantly lower after TIPS.CONCLUSIONS: Transjugular intrahepatic portosystemic stent shunt placement is associated with an increase in central venous pressure and an improvement of global blood flow (cardiac index and stroke volume index) in patients with portal hypertension.

U2 - 10.1016/j.jcrc.2014.06.028

DO - 10.1016/j.jcrc.2014.06.028

M3 - SCORING: Journal article

C2 - 25220530

VL - 29

SP - 1001

EP - 1005

JO - J CRIT CARE

JF - J CRIT CARE

SN - 0883-9441

IS - 6

ER -