The effect of recent chemotherapy in aorto-iliac aneurysm repair

Nikolaos Tsilimparis; Joseph J Ricotta; Anand Dayama; James G Reeves; Sebastian Perez; John F Sweeney

doi:10.1177/1708538112473970

The effect of recent chemotherapy in aorto-iliac aneurysm repair

Standard

The effect of recent chemotherapy in aorto-iliac aneurysm repair. / Tsilimparis, Nikolaos; Ricotta, Joseph J; Dayama, Anand; Reeves, James G; Perez, Sebastian; Sweeney, John F.

in: VASCULAR, Jahrgang 22, Nr. 2, 04.2014, S. 98-104.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Tsilimparis, N, Ricotta, JJ, Dayama, A, Reeves, JG, Perez, S & Sweeney, JF 2014, 'The effect of recent chemotherapy in aorto-iliac aneurysm repair', VASCULAR, Jg. 22, Nr. 2, S. 98-104. https://doi.org/10.1177/1708538112473970

APA

Tsilimparis, N., Ricotta, J. J., Dayama, A., Reeves, J. G., Perez, S., & Sweeney, J. F. (2014). The effect of recent chemotherapy in aorto-iliac aneurysm repair. VASCULAR, 22(2), 98-104. https://doi.org/10.1177/1708538112473970

Vancouver

Tsilimparis N, Ricotta JJ, Dayama A, Reeves JG, Perez S, Sweeney JF. The effect of recent chemotherapy in aorto-iliac aneurysm repair. VASCULAR. 2014 Apr;22(2):98-104. https://doi.org/10.1177/1708538112473970

Bibtex

@article{a9b32e74174b436e95a5bd80ee297db3,

title = "The effect of recent chemotherapy in aorto-iliac aneurysm repair",

abstract = "The aim of the study was to investigate the effect of recent chemotherapy (Chx) on outcome of aorto-iliac aneurysm (AAA) repair. The 2005-2010 American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database was queried to identify vascular patients undergoing AAA repair within 30 days after Chx. Seventy-one patients underwent AAA repair within 30 days of receiving Chx, group A (71 ± 8.4 years, 77.5% males) and 20,024 patients underwent AAA repair without prior Chx, group B (73 ± 9 years, 79.2% males). The two groups did not significantly differ with respect to open or endovascular repair (open repair A: 32%, B: 35%, P = 0.66). However, patients in group A presented more often as emergent cases (A: 27%, B: 12%, P = 0.001). Multivariable regression analysis for emergent cases after adjustment for relevant confounders also demonstrated that patients with recent Chx present more often as emergency (P = 0.001, odds ratio [OR]: 2.4). Thirty-day non-surgical complications were more common in group A (A: 25%, B: 16.5%, P = 0.046) while surgical complications were equivalent (A: 15.5%, B: 12.3%, P = 0.414). Risk of death was significantly higher in group A in univariate analysis (A: 13%, B: 5%, P = 0.005, OR: 2.6). Patients who receive Chx within 30 days prior to AAA repair present more frequently as emergencies leading to higher mortality. The reason for this cannot be sufficiently explained by the current database but patient selection for elective repair or the effect of Chx on the natural course of AAA may play a role. ",

keywords = "Aged, Antineoplastic Agents/adverse effects, Aortic Aneurysm, Abdominal/mortality, Aortic Rupture/surgery, Blood Vessel Prosthesis Implantation/adverse effects, Chi-Square Distribution, Elective Surgical Procedures, Emergencies, Endovascular Procedures/adverse effects, Female, Humans, Iliac Aneurysm/mortality, Logistic Models, Male, Middle Aged, Multivariate Analysis, Odds Ratio, Patient Selection, Risk Assessment, Risk Factors, Time Factors, Treatment Outcome",

author = "Nikolaos Tsilimparis and Ricotta, {Joseph J} and Anand Dayama and Reeves, {James G} and Sebastian Perez and Sweeney, {John F}",

year = "2014",

month = apr,

doi = "10.1177/1708538112473970",

language = "English",

volume = "22",

pages = "98--104",

journal = "VASCULAR",

issn = "1708-5381",

publisher = "SAGE Publications",

number = "2",

}

RIS

TY - JOUR

T1 - The effect of recent chemotherapy in aorto-iliac aneurysm repair

AU - Tsilimparis, Nikolaos

AU - Ricotta, Joseph J

AU - Dayama, Anand

AU - Reeves, James G

AU - Perez, Sebastian

AU - Sweeney, John F

PY - 2014/4

Y1 - 2014/4

N2 - The aim of the study was to investigate the effect of recent chemotherapy (Chx) on outcome of aorto-iliac aneurysm (AAA) repair. The 2005-2010 American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database was queried to identify vascular patients undergoing AAA repair within 30 days after Chx. Seventy-one patients underwent AAA repair within 30 days of receiving Chx, group A (71 ± 8.4 years, 77.5% males) and 20,024 patients underwent AAA repair without prior Chx, group B (73 ± 9 years, 79.2% males). The two groups did not significantly differ with respect to open or endovascular repair (open repair A: 32%, B: 35%, P = 0.66). However, patients in group A presented more often as emergent cases (A: 27%, B: 12%, P = 0.001). Multivariable regression analysis for emergent cases after adjustment for relevant confounders also demonstrated that patients with recent Chx present more often as emergency (P = 0.001, odds ratio [OR]: 2.4). Thirty-day non-surgical complications were more common in group A (A: 25%, B: 16.5%, P = 0.046) while surgical complications were equivalent (A: 15.5%, B: 12.3%, P = 0.414). Risk of death was significantly higher in group A in univariate analysis (A: 13%, B: 5%, P = 0.005, OR: 2.6). Patients who receive Chx within 30 days prior to AAA repair present more frequently as emergencies leading to higher mortality. The reason for this cannot be sufficiently explained by the current database but patient selection for elective repair or the effect of Chx on the natural course of AAA may play a role.

AB - The aim of the study was to investigate the effect of recent chemotherapy (Chx) on outcome of aorto-iliac aneurysm (AAA) repair. The 2005-2010 American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database was queried to identify vascular patients undergoing AAA repair within 30 days after Chx. Seventy-one patients underwent AAA repair within 30 days of receiving Chx, group A (71 ± 8.4 years, 77.5% males) and 20,024 patients underwent AAA repair without prior Chx, group B (73 ± 9 years, 79.2% males). The two groups did not significantly differ with respect to open or endovascular repair (open repair A: 32%, B: 35%, P = 0.66). However, patients in group A presented more often as emergent cases (A: 27%, B: 12%, P = 0.001). Multivariable regression analysis for emergent cases after adjustment for relevant confounders also demonstrated that patients with recent Chx present more often as emergency (P = 0.001, odds ratio [OR]: 2.4). Thirty-day non-surgical complications were more common in group A (A: 25%, B: 16.5%, P = 0.046) while surgical complications were equivalent (A: 15.5%, B: 12.3%, P = 0.414). Risk of death was significantly higher in group A in univariate analysis (A: 13%, B: 5%, P = 0.005, OR: 2.6). Patients who receive Chx within 30 days prior to AAA repair present more frequently as emergencies leading to higher mortality. The reason for this cannot be sufficiently explained by the current database but patient selection for elective repair or the effect of Chx on the natural course of AAA may play a role.

KW - Aged

KW - Antineoplastic Agents/adverse effects

KW - Aortic Aneurysm, Abdominal/mortality

KW - Aortic Rupture/surgery

KW - Blood Vessel Prosthesis Implantation/adverse effects

KW - Chi-Square Distribution

KW - Elective Surgical Procedures

KW - Emergencies

KW - Endovascular Procedures/adverse effects

KW - Female

KW - Humans

KW - Iliac Aneurysm/mortality

KW - Logistic Models

KW - Male

KW - Middle Aged

KW - Multivariate Analysis

KW - Odds Ratio

KW - Patient Selection

KW - Risk Assessment

KW - Risk Factors

KW - Time Factors

KW - Treatment Outcome

U2 - 10.1177/1708538112473970

DO - 10.1177/1708538112473970

M3 - SCORING: Journal article

C2 - 23512896

VL - 22

SP - 98

EP - 104

JO - VASCULAR

JF - VASCULAR

SN - 1708-5381

IS - 2

ER -