The effect of homeopathic plant extract solutions on the cell proliferation of human cutaneous fibroblasts in vitro.

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The effect of homeopathic plant extract solutions on the cell proliferation of human cutaneous fibroblasts in vitro. / Valentiner, U; Weiser, M; Moll, Ingrid; Schumacher, U.

in: FORSCH KOMP KLAS NAT, Jahrgang 10, Nr. 3, 3, 2003, S. 122-127.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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Valentiner U, Weiser M, Moll I, Schumacher U. The effect of homeopathic plant extract solutions on the cell proliferation of human cutaneous fibroblasts in vitro. FORSCH KOMP KLAS NAT. 2003;10(3):122-127. 3.

Bibtex

@article{c1e2d60055624c0bb556b05f7ba13fb2,
title = "The effect of homeopathic plant extract solutions on the cell proliferation of human cutaneous fibroblasts in vitro.",
abstract = "BACKGROUND: According to homotoxicology illness is defined as an overload of the connective tissue matrix with toxic substances, the homotoxins. In order to support elimination of these homotoxins, complex homeopathic medicines were developed. Fibroblasts are the local cells of this matrix and produce and modulate the composition of the extracellular matrix (ECM) in every organ. OBJECTIVE: In this study, the effect of 17 potentiated plant extracts, which are components of some antihomotoxic remedies, on the cell proliferation of human cutaneous fibroblasts (F54) was analyzed as an indication of their influence on the ECM. MATERIAL AND METHODS: Cell proliferation of the F54 cells was measured by a colorimetric XTT-based assay kit. RESULTS: Six of the tested agents had no effect on the cell proliferation of fibroblasts; 11 plant extracts had a dose-dependent inhibitory effect on cell proliferation. CONCLUSIONS: As the modulation of the ECM is dependent on the activity of the fibroblasts, these results indicate that the plant extracts may modulate the composition of the ECM via the inhibitory effect on fibroblasts cell growth.",
author = "U Valentiner and M Weiser and Ingrid Moll and U Schumacher",
year = "2003",
language = "Deutsch",
volume = "10",
pages = "122--127",
number = "3",

}

RIS

TY - JOUR

T1 - The effect of homeopathic plant extract solutions on the cell proliferation of human cutaneous fibroblasts in vitro.

AU - Valentiner, U

AU - Weiser, M

AU - Moll, Ingrid

AU - Schumacher, U

PY - 2003

Y1 - 2003

N2 - BACKGROUND: According to homotoxicology illness is defined as an overload of the connective tissue matrix with toxic substances, the homotoxins. In order to support elimination of these homotoxins, complex homeopathic medicines were developed. Fibroblasts are the local cells of this matrix and produce and modulate the composition of the extracellular matrix (ECM) in every organ. OBJECTIVE: In this study, the effect of 17 potentiated plant extracts, which are components of some antihomotoxic remedies, on the cell proliferation of human cutaneous fibroblasts (F54) was analyzed as an indication of their influence on the ECM. MATERIAL AND METHODS: Cell proliferation of the F54 cells was measured by a colorimetric XTT-based assay kit. RESULTS: Six of the tested agents had no effect on the cell proliferation of fibroblasts; 11 plant extracts had a dose-dependent inhibitory effect on cell proliferation. CONCLUSIONS: As the modulation of the ECM is dependent on the activity of the fibroblasts, these results indicate that the plant extracts may modulate the composition of the ECM via the inhibitory effect on fibroblasts cell growth.

AB - BACKGROUND: According to homotoxicology illness is defined as an overload of the connective tissue matrix with toxic substances, the homotoxins. In order to support elimination of these homotoxins, complex homeopathic medicines were developed. Fibroblasts are the local cells of this matrix and produce and modulate the composition of the extracellular matrix (ECM) in every organ. OBJECTIVE: In this study, the effect of 17 potentiated plant extracts, which are components of some antihomotoxic remedies, on the cell proliferation of human cutaneous fibroblasts (F54) was analyzed as an indication of their influence on the ECM. MATERIAL AND METHODS: Cell proliferation of the F54 cells was measured by a colorimetric XTT-based assay kit. RESULTS: Six of the tested agents had no effect on the cell proliferation of fibroblasts; 11 plant extracts had a dose-dependent inhibitory effect on cell proliferation. CONCLUSIONS: As the modulation of the ECM is dependent on the activity of the fibroblasts, these results indicate that the plant extracts may modulate the composition of the ECM via the inhibitory effect on fibroblasts cell growth.

M3 - SCORING: Zeitschriftenaufsatz

VL - 10

SP - 122

EP - 127

IS - 3

M1 - 3

ER -