The detection of oral pre- malignant lesions with an autofluorescence based imaging system (VELscope™) - a single blinded clinical evaluation
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The detection of oral pre- malignant lesions with an autofluorescence based imaging system (VELscope™) - a single blinded clinical evaluation. / Hanken, Henning; Kraatz, Juliane; Smeets, Ralf; Heiland, Max; Assaf, Alexandre Thomas; Blessmann, Marco; Eichhorn, Wolfgang; Clauditz, Till Sebastian; Gröbe, Alexander; Kolk, Andreas; Rana, Madiha.
in: HEAD FACE MED, Jahrgang 9, 01.01.2013, S. 23.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - The detection of oral pre- malignant lesions with an autofluorescence based imaging system (VELscope™) - a single blinded clinical evaluation
AU - Hanken, Henning
AU - Kraatz, Juliane
AU - Smeets, Ralf
AU - Heiland, Max
AU - Assaf, Alexandre Thomas
AU - Blessmann, Marco
AU - Eichhorn, Wolfgang
AU - Clauditz, Till Sebastian
AU - Gröbe, Alexander
AU - Kolk, Andreas
AU - Rana, Madiha
N1 - Arbeit ist doppelt gelistet, als Original und titelgleich als Erratum, da der Autor Assaf "vergessen" wurde. Das Erratum listet Assaf als Autor.
PY - 2013/1/1
Y1 - 2013/1/1
N2 - OBJECTIVE: The disease specific five-year survival rate especially for patients with advanced oral cancer has not improved significantly over the period of time. The most effective way of combating this dilemma is an early detection, diagnosis and eradication of early-stage lesions and their precursors. The use of VELscope® using an autofluorescence as a diagnostic tool might be useful in early detection of oral malignant lesions.MATERIALS AND METHODS: 120 patients with suspicious oral premalignant lesions were examined with two examination methods. They were randomly divided into two groups. Group 1 was examined conventional with white-light and group 2 was examined additionally to the white-light-examination with an autofluorescence visualization device, VELscope®. Biopsies were obtained from all suspicious areas identified in both examination groups (n = 52). The diagnostic strategies were compared regarding sensitivity and specificity.RESULTS: Based upon the result, use of the VELscope® leads to a higher sensitivity (22.0%), but regarding specificity the additional use of the VELscope® is inferior (8.4%).CONCLUSION: The VELscope device is a simple, non-invasive test of the oral mucosa, which can help the experienced clinician to find oral precursor malignant lesions.
AB - OBJECTIVE: The disease specific five-year survival rate especially for patients with advanced oral cancer has not improved significantly over the period of time. The most effective way of combating this dilemma is an early detection, diagnosis and eradication of early-stage lesions and their precursors. The use of VELscope® using an autofluorescence as a diagnostic tool might be useful in early detection of oral malignant lesions.MATERIALS AND METHODS: 120 patients with suspicious oral premalignant lesions were examined with two examination methods. They were randomly divided into two groups. Group 1 was examined conventional with white-light and group 2 was examined additionally to the white-light-examination with an autofluorescence visualization device, VELscope®. Biopsies were obtained from all suspicious areas identified in both examination groups (n = 52). The diagnostic strategies were compared regarding sensitivity and specificity.RESULTS: Based upon the result, use of the VELscope® leads to a higher sensitivity (22.0%), but regarding specificity the additional use of the VELscope® is inferior (8.4%).CONCLUSION: The VELscope device is a simple, non-invasive test of the oral mucosa, which can help the experienced clinician to find oral precursor malignant lesions.
U2 - 10.1186/1746-160X-9-23
DO - 10.1186/1746-160X-9-23
M3 - SCORING: Journal article
C2 - 23967796
VL - 9
SP - 23
JO - HEAD FACE MED
JF - HEAD FACE MED
SN - 1746-160X
ER -