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The Condensation of Collagen Leads to an Extended Standing Time and a Decreased Pro-inflammatory Tissue Response to a Newly Developed Pericardium-based Barrier Membrane for Guided Bone Regeneration

Standard

The Condensation of Collagen Leads to an Extended Standing Time and a Decreased Pro-inflammatory Tissue Response to a Newly Developed Pericardium-based Barrier Membrane for Guided Bone Regeneration. / Gueldenpfennig, Tristan; Houshmand, Alireza; Najman, Stevo; Stojanovic, Sanja; Korzinskas, Tadas; Smeets, Ralf; Gosau, Martin; Pissarek, Jens; Emmert, Steffen; Jung, Ole; Barbeck, Mike.

in: IN VIVO, Jahrgang 34, Nr. 3, 02.05.2020, S. 985-1000.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Gueldenpfennig, T, Houshmand, A, Najman, S, Stojanovic, S, Korzinskas, T, Smeets, R, Gosau, M, Pissarek, J, Emmert, S, Jung, O & Barbeck, M 2020, 'The Condensation of Collagen Leads to an Extended Standing Time and a Decreased Pro-inflammatory Tissue Response to a Newly Developed Pericardium-based Barrier Membrane for Guided Bone Regeneration', IN VIVO, Jg. 34, Nr. 3, S. 985-1000. https://doi.org/10.21873/invivo.11867

APA

Gueldenpfennig, T., Houshmand, A., Najman, S., Stojanovic, S., Korzinskas, T., Smeets, R., Gosau, M., Pissarek, J., Emmert, S., Jung, O., & Barbeck, M. (2020). The Condensation of Collagen Leads to an Extended Standing Time and a Decreased Pro-inflammatory Tissue Response to a Newly Developed Pericardium-based Barrier Membrane for Guided Bone Regeneration. IN VIVO, 34(3), 985-1000. https://doi.org/10.21873/invivo.11867

Vancouver

Gueldenpfennig T, Houshmand A, Najman S, Stojanovic S, Korzinskas T, Smeets R et al. The Condensation of Collagen Leads to an Extended Standing Time and a Decreased Pro-inflammatory Tissue Response to a Newly Developed Pericardium-based Barrier Membrane for Guided Bone Regeneration. IN VIVO. 2020 Mai 2;34(3):985-1000. https://doi.org/10.21873/invivo.11867

Bibtex

@article{7e66b63fc88a44049f74d7565aa308e7,
title = "The Condensation of Collagen Leads to an Extended Standing Time and a Decreased Pro-inflammatory Tissue Response to a Newly Developed Pericardium-based Barrier Membrane for Guided Bone Regeneration",
abstract = "BACKGROUND/AIM: A new manufacturing process has been established for the condensation of collagen derived from porcine pericardium to develop a new dental barrier membrane (CPM) that can provide a long barrier functionality. A native collagen membrane (PM) was used as control.MATERIALS AND METHODS: Established in vitro procedures using L929 and MC3T3 cells were used for cytocompatibility analyses. For the in vivo study, subcutaneous implantation of both membrane types in 40 BALB/c mice and established histological, immuno histochemical and histomorphometrical methods were conducted.RESULTS: Both the in vitro and in vivo results revealed that the CPM has a biocompatibility profile comparable to that of the control membrane. The new CPM induced a tissue reaction including more M2-macrophages.CONCLUSION: The CPM is fully biocompatible and seems to support the early healing process. Moreover, the new biomaterial seems to prevent cell ingrowth for a longer period of time, making it ideally suited for GBR procedures.",
keywords = "Animals, Biocompatible Materials, Biomarkers, Bone Regeneration, Collagen/metabolism, Female, Fibroblasts, Guided Tissue Regeneration, Immunohistochemistry, Macrophages/metabolism, Membranes, Artificial, Mice, Pericardium, Proteolysis, Swine, Time Factors",
author = "Tristan Gueldenpfennig and Alireza Houshmand and Stevo Najman and Sanja Stojanovic and Tadas Korzinskas and Ralf Smeets and Martin Gosau and Jens Pissarek and Steffen Emmert and Ole Jung and Mike Barbeck",
note = "Copyright{\textcopyright} 2020, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.",
year = "2020",
month = may,
day = "2",
doi = "10.21873/invivo.11867",
language = "English",
volume = "34",
pages = "985--1000",
journal = "IN VIVO",
issn = "0258-851X",
publisher = "International Institute of Anticancer Research",
number = "3",

}

RIS

TY - JOUR

T1 - The Condensation of Collagen Leads to an Extended Standing Time and a Decreased Pro-inflammatory Tissue Response to a Newly Developed Pericardium-based Barrier Membrane for Guided Bone Regeneration

AU - Gueldenpfennig, Tristan

AU - Houshmand, Alireza

AU - Najman, Stevo

AU - Stojanovic, Sanja

AU - Korzinskas, Tadas

AU - Smeets, Ralf

AU - Gosau, Martin

AU - Pissarek, Jens

AU - Emmert, Steffen

AU - Jung, Ole

AU - Barbeck, Mike

N1 - Copyright© 2020, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

PY - 2020/5/2

Y1 - 2020/5/2

N2 - BACKGROUND/AIM: A new manufacturing process has been established for the condensation of collagen derived from porcine pericardium to develop a new dental barrier membrane (CPM) that can provide a long barrier functionality. A native collagen membrane (PM) was used as control.MATERIALS AND METHODS: Established in vitro procedures using L929 and MC3T3 cells were used for cytocompatibility analyses. For the in vivo study, subcutaneous implantation of both membrane types in 40 BALB/c mice and established histological, immuno histochemical and histomorphometrical methods were conducted.RESULTS: Both the in vitro and in vivo results revealed that the CPM has a biocompatibility profile comparable to that of the control membrane. The new CPM induced a tissue reaction including more M2-macrophages.CONCLUSION: The CPM is fully biocompatible and seems to support the early healing process. Moreover, the new biomaterial seems to prevent cell ingrowth for a longer period of time, making it ideally suited for GBR procedures.

AB - BACKGROUND/AIM: A new manufacturing process has been established for the condensation of collagen derived from porcine pericardium to develop a new dental barrier membrane (CPM) that can provide a long barrier functionality. A native collagen membrane (PM) was used as control.MATERIALS AND METHODS: Established in vitro procedures using L929 and MC3T3 cells were used for cytocompatibility analyses. For the in vivo study, subcutaneous implantation of both membrane types in 40 BALB/c mice and established histological, immuno histochemical and histomorphometrical methods were conducted.RESULTS: Both the in vitro and in vivo results revealed that the CPM has a biocompatibility profile comparable to that of the control membrane. The new CPM induced a tissue reaction including more M2-macrophages.CONCLUSION: The CPM is fully biocompatible and seems to support the early healing process. Moreover, the new biomaterial seems to prevent cell ingrowth for a longer period of time, making it ideally suited for GBR procedures.

KW - Animals

KW - Biocompatible Materials

KW - Biomarkers

KW - Bone Regeneration

KW - Collagen/metabolism

KW - Female

KW - Fibroblasts

KW - Guided Tissue Regeneration

KW - Immunohistochemistry

KW - Macrophages/metabolism

KW - Membranes, Artificial

KW - Mice

KW - Pericardium

KW - Proteolysis

KW - Swine

KW - Time Factors

U2 - 10.21873/invivo.11867

DO - 10.21873/invivo.11867

M3 - SCORING: Journal article

C2 - 32354884

VL - 34

SP - 985

EP - 1000

JO - IN VIVO

JF - IN VIVO

SN - 0258-851X

IS - 3

ER -