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The AVICH Score

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The AVICH Score : A Novel Grading System to Predict Clinical Outcome in Arteriovenous Malformation-Related Intracerebral Hemorrhage. / Neidert, Marian C; Lawton, Michael T; Mader, Marius; Seifert, Burkhardt; Valavanis, Antonios; Regli, Luca; Bozinov, Oliver; Burkhardt, Jan-Karl.

in: WORLD NEUROSURG, Jahrgang 92, 08.2016, S. 292-7.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Neidert, MC, Lawton, MT, Mader, M, Seifert, B, Valavanis, A, Regli, L, Bozinov, O & Burkhardt, J-K 2016, 'The AVICH Score: A Novel Grading System to Predict Clinical Outcome in Arteriovenous Malformation-Related Intracerebral Hemorrhage', WORLD NEUROSURG, Jg. 92, S. 292-7. https://doi.org/10.1016/j.wneu.2016.04.080

APA

Neidert, M. C., Lawton, M. T., Mader, M., Seifert, B., Valavanis, A., Regli, L., Bozinov, O., & Burkhardt, J-K. (2016). The AVICH Score: A Novel Grading System to Predict Clinical Outcome in Arteriovenous Malformation-Related Intracerebral Hemorrhage. WORLD NEUROSURG, 92, 292-7. https://doi.org/10.1016/j.wneu.2016.04.080

Vancouver

Neidert MC, Lawton MT, Mader M, Seifert B, Valavanis A, Regli L et al. The AVICH Score: A Novel Grading System to Predict Clinical Outcome in Arteriovenous Malformation-Related Intracerebral Hemorrhage. WORLD NEUROSURG. 2016 Aug;92:292-7. https://doi.org/10.1016/j.wneu.2016.04.080

Bibtex

@article{2925bd998df5436bafdb26c02c56e976,
title = "The AVICH Score: A Novel Grading System to Predict Clinical Outcome in Arteriovenous Malformation-Related Intracerebral Hemorrhage",
abstract = "OBJECTIVE: To establish an arteriovenous malformation (AVM) grading score for patients with ruptured AVM and associated intracerebral hemorrhage (ICH) to predict clinical outcome.METHODS: Patient data from January 2006 to December 2013 with newly diagnosed ICH caused by ruptured AVM and a modified Rankin Scale (mRS) score <2 before ICH were included for this analysis. Clinical outcome was dichotomized in favorable (mRS score, 0-2) and unfavorable (mRS score, 3-6) to find predictors for outcome and to establish a new score based on the areas under the receiver-operating characteristic curves (AUROC) at 3 months, 1 year, and at last follow-up (mean, 31 months).RESULTS: A total of 67 patients (mean age, 41 years; 66% male) were analyzed including 39 patients with favorable and 28 with unfavorable outcome. Intraventricular hemorrhage (P = 0.048), ICH score (P = 0.003), AVM size (P < 0.001), Spetzler-Martin grade (P < 0.001), nidus structure (P = 0.005), Lawton-Young grade (P = 0.015), and supplemented Spetzler-Martin score (P < 0.001) were significant predictors for clinical outcome in ruptured AVMs. Based on these results, we created a new score named the AVICH (AVM-related ICH) score, which showed an AUROC of 0.842 compared to 0.789 for the supplemented Spetzler-Martin grading system and 0.703 for the ICH score regarding clinical outcome at last follow-up.CONCLUSIONS: Based on the AUROC analysis, the AVICH score predicts outcome of patients with ruptured AVM and associated ICH better than the ICH score, the Spetzler-Martin, or the supplemented Spetzler-Martin grading system. An external validation is needed before the AVICH score is tested in a prospective multicenter cohort.",
keywords = "Adult, Cerebral Hemorrhage, Embolization, Therapeutic, Female, Humans, Intracranial Arteriovenous Malformations, Longitudinal Studies, Male, Middle Aged, Outcome Assessment (Health Care), Predictive Value of Tests, ROC Curve, Retrospective Studies, Severity of Illness Index, Treatment Outcome, Young Adult, Journal Article",
author = "Neidert, {Marian C} and Lawton, {Michael T} and Marius Mader and Burkhardt Seifert and Antonios Valavanis and Luca Regli and Oliver Bozinov and Jan-Karl Burkhardt",
note = "Copyright {\textcopyright} 2016 Elsevier Inc. All rights reserved.",
year = "2016",
month = aug,
doi = "10.1016/j.wneu.2016.04.080",
language = "English",
volume = "92",
pages = "292--7",
journal = "WORLD NEUROSURG",
issn = "1878-8750",
publisher = "Elsevier Inc.",

}

RIS

TY - JOUR

T1 - The AVICH Score

T2 - A Novel Grading System to Predict Clinical Outcome in Arteriovenous Malformation-Related Intracerebral Hemorrhage

AU - Neidert, Marian C

AU - Lawton, Michael T

AU - Mader, Marius

AU - Seifert, Burkhardt

AU - Valavanis, Antonios

AU - Regli, Luca

AU - Bozinov, Oliver

AU - Burkhardt, Jan-Karl

N1 - Copyright © 2016 Elsevier Inc. All rights reserved.

PY - 2016/8

Y1 - 2016/8

N2 - OBJECTIVE: To establish an arteriovenous malformation (AVM) grading score for patients with ruptured AVM and associated intracerebral hemorrhage (ICH) to predict clinical outcome.METHODS: Patient data from January 2006 to December 2013 with newly diagnosed ICH caused by ruptured AVM and a modified Rankin Scale (mRS) score <2 before ICH were included for this analysis. Clinical outcome was dichotomized in favorable (mRS score, 0-2) and unfavorable (mRS score, 3-6) to find predictors for outcome and to establish a new score based on the areas under the receiver-operating characteristic curves (AUROC) at 3 months, 1 year, and at last follow-up (mean, 31 months).RESULTS: A total of 67 patients (mean age, 41 years; 66% male) were analyzed including 39 patients with favorable and 28 with unfavorable outcome. Intraventricular hemorrhage (P = 0.048), ICH score (P = 0.003), AVM size (P < 0.001), Spetzler-Martin grade (P < 0.001), nidus structure (P = 0.005), Lawton-Young grade (P = 0.015), and supplemented Spetzler-Martin score (P < 0.001) were significant predictors for clinical outcome in ruptured AVMs. Based on these results, we created a new score named the AVICH (AVM-related ICH) score, which showed an AUROC of 0.842 compared to 0.789 for the supplemented Spetzler-Martin grading system and 0.703 for the ICH score regarding clinical outcome at last follow-up.CONCLUSIONS: Based on the AUROC analysis, the AVICH score predicts outcome of patients with ruptured AVM and associated ICH better than the ICH score, the Spetzler-Martin, or the supplemented Spetzler-Martin grading system. An external validation is needed before the AVICH score is tested in a prospective multicenter cohort.

AB - OBJECTIVE: To establish an arteriovenous malformation (AVM) grading score for patients with ruptured AVM and associated intracerebral hemorrhage (ICH) to predict clinical outcome.METHODS: Patient data from January 2006 to December 2013 with newly diagnosed ICH caused by ruptured AVM and a modified Rankin Scale (mRS) score <2 before ICH were included for this analysis. Clinical outcome was dichotomized in favorable (mRS score, 0-2) and unfavorable (mRS score, 3-6) to find predictors for outcome and to establish a new score based on the areas under the receiver-operating characteristic curves (AUROC) at 3 months, 1 year, and at last follow-up (mean, 31 months).RESULTS: A total of 67 patients (mean age, 41 years; 66% male) were analyzed including 39 patients with favorable and 28 with unfavorable outcome. Intraventricular hemorrhage (P = 0.048), ICH score (P = 0.003), AVM size (P < 0.001), Spetzler-Martin grade (P < 0.001), nidus structure (P = 0.005), Lawton-Young grade (P = 0.015), and supplemented Spetzler-Martin score (P < 0.001) were significant predictors for clinical outcome in ruptured AVMs. Based on these results, we created a new score named the AVICH (AVM-related ICH) score, which showed an AUROC of 0.842 compared to 0.789 for the supplemented Spetzler-Martin grading system and 0.703 for the ICH score regarding clinical outcome at last follow-up.CONCLUSIONS: Based on the AUROC analysis, the AVICH score predicts outcome of patients with ruptured AVM and associated ICH better than the ICH score, the Spetzler-Martin, or the supplemented Spetzler-Martin grading system. An external validation is needed before the AVICH score is tested in a prospective multicenter cohort.

KW - Adult

KW - Cerebral Hemorrhage

KW - Embolization, Therapeutic

KW - Female

KW - Humans

KW - Intracranial Arteriovenous Malformations

KW - Longitudinal Studies

KW - Male

KW - Middle Aged

KW - Outcome Assessment (Health Care)

KW - Predictive Value of Tests

KW - ROC Curve

KW - Retrospective Studies

KW - Severity of Illness Index

KW - Treatment Outcome

KW - Young Adult

KW - Journal Article

U2 - 10.1016/j.wneu.2016.04.080

DO - 10.1016/j.wneu.2016.04.080

M3 - SCORING: Journal article

C2 - 27150647

VL - 92

SP - 292

EP - 297

JO - WORLD NEUROSURG

JF - WORLD NEUROSURG

SN - 1878-8750

ER -