The amygdaloid body of two carnivore species: The feliform banded mongoose and the caniform domestic ferret

TY - JOUR

T1 - The amygdaloid body of two carnivore species: The feliform banded mongoose and the caniform domestic ferret

AU - Pillay, Sashrika

AU - Bhagwandin, Adhil

AU - Bertelsen, Mads F.

AU - Patzke, Nina

AU - Engler, Gerhard

AU - Engel, Andreas K.

AU - Manger, Paul R.

N1 - Funding Information: No specific acknowledgements. Publisher Copyright: © 2020 Wiley Periodicals LLC Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

PY - 2021/1

Y1 - 2021/1

N2 - The current study provides an analysis of the cytoarchitecture, myeloarchitecture, and chemoarchitecture of the amygdaloid body of the banded mongoose (Mungos mungo) and domestic ferret (Mustela putorius furo). Using architectural and immunohistochemical stains, we observe that the organization of the nuclear and cortical portions of the amygdaloid complex is very similar in both species. The one major difference is the presence of a cortex-amygdala transition zone observed in the domestic ferret that is absent in the banded mongoose. In addition, the chemoarchitecture is, for the most part, quite similar in the two species, but several variances, such as differing densities of neurons expressing the calcium-binding proteins in specific nuclei are noted. Despite this, certain aspects of the chemoarchitecture, such as the cholinergic innervation of the magnocellular division of the basal nuclear cluster and the presence of doublecortin expressing neurons in the shell division of the accessory basal nuclear cluster, appear to be consistent features of the Eutherian mammal amygdala. The domestic ferret presented with an overall lower myelin density throughout the amygdaloid body than the banded mongoose, a feature that may reflect artificial selection in the process of domestication for increased juvenile-like behavior in the adult domestic ferret, such as a muted fear response. The shared, but temporally distant, ancestry of the banded mongoose and domestic ferret allows us to generate observations relevant to understanding the relative influence that phylogenetic constraints, adaptive evolutionary plasticity, and the domestication process may play in the organization and chemoarchitecture of the amygdaloid body.

AB - The current study provides an analysis of the cytoarchitecture, myeloarchitecture, and chemoarchitecture of the amygdaloid body of the banded mongoose (Mungos mungo) and domestic ferret (Mustela putorius furo). Using architectural and immunohistochemical stains, we observe that the organization of the nuclear and cortical portions of the amygdaloid complex is very similar in both species. The one major difference is the presence of a cortex-amygdala transition zone observed in the domestic ferret that is absent in the banded mongoose. In addition, the chemoarchitecture is, for the most part, quite similar in the two species, but several variances, such as differing densities of neurons expressing the calcium-binding proteins in specific nuclei are noted. Despite this, certain aspects of the chemoarchitecture, such as the cholinergic innervation of the magnocellular division of the basal nuclear cluster and the presence of doublecortin expressing neurons in the shell division of the accessory basal nuclear cluster, appear to be consistent features of the Eutherian mammal amygdala. The domestic ferret presented with an overall lower myelin density throughout the amygdaloid body than the banded mongoose, a feature that may reflect artificial selection in the process of domestication for increased juvenile-like behavior in the adult domestic ferret, such as a muted fear response. The shared, but temporally distant, ancestry of the banded mongoose and domestic ferret allows us to generate observations relevant to understanding the relative influence that phylogenetic constraints, adaptive evolutionary plasticity, and the domestication process may play in the organization and chemoarchitecture of the amygdaloid body.

KW - amygdala

KW - Carnivora

KW - chemoarchitecture

KW - cytoarchitecture

KW - myeloarchitecture

KW - RRID: AB_10000323

KW - RRID: AB_10000340

KW - RRID: AB_10000343

KW - RRID: AB_2079751

KW - RRID: AB_2187552

KW - RRID: AB_91545

KW - RRID: AB_AB2088494

KW - RRUD: AB_509997

KW - social behavior

UR - http://www.scopus.com/inward/record.url?scp=85092710992&partnerID=8YFLogxK

U2 - 10.1002/cne.25046

DO - 10.1002/cne.25046

M3 - SCORING: Journal article

C2 - 33009661

AN - SCOPUS:85092710992

VL - 529

SP - 28

EP - 51

JO - J COMP NEUROL

JF - J COMP NEUROL

SN - 0021-9967

IS - 1

ER -