[Technological aspects of regenerative medicine and tissue engineering of articular cartilage].
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[Technological aspects of regenerative medicine and tissue engineering of articular cartilage]. / Pörtner, R; Meenen, Norbert.
in: HANDCHIR MIKROCHIR P, Jahrgang 42, Nr. 6, 6, 2010, S. 329-336.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - [Technological aspects of regenerative medicine and tissue engineering of articular cartilage].
AU - Pörtner, R
AU - Meenen, Norbert
PY - 2010
Y1 - 2010
N2 - The main problem in the treatment of orthopaedic joint-surface defects will be solved by tissue engineering of cartilage implants. Entire biological osteochondral implants can be grown from autologous cells of the patient. The nutrition of articular cartilage is by diffusion only. Therefore the chondrocyte as the unique cell type is perfectly dedicated to the tissue culture approach. Engineering techniques of bioreactors are prerequisite for these biological and medical solutions. With our tissue engineering project for the generation of osteochondral constructs we demonstrate possibilities and characteristics of bioreactors for the modification of cell culture techniques and mechanical conditioning of cartilage tissue for fully operable implants.
AB - The main problem in the treatment of orthopaedic joint-surface defects will be solved by tissue engineering of cartilage implants. Entire biological osteochondral implants can be grown from autologous cells of the patient. The nutrition of articular cartilage is by diffusion only. Therefore the chondrocyte as the unique cell type is perfectly dedicated to the tissue culture approach. Engineering techniques of bioreactors are prerequisite for these biological and medical solutions. With our tissue engineering project for the generation of osteochondral constructs we demonstrate possibilities and characteristics of bioreactors for the modification of cell culture techniques and mechanical conditioning of cartilage tissue for fully operable implants.
KW - Humans
KW - Tissue Engineering/methods
KW - Ceramics
KW - Bioreactors
KW - Cartilage, Articular/surgery
KW - Guided Tissue Regeneration/methods
KW - Hyaline Cartilage/surgery/transplantation
KW - Regenerative Medicine/methods
KW - Tissue Culture Techniques/methods
KW - Tissue Scaffolds
KW - Humans
KW - Tissue Engineering/methods
KW - Ceramics
KW - Bioreactors
KW - Cartilage, Articular/surgery
KW - Guided Tissue Regeneration/methods
KW - Hyaline Cartilage/surgery/transplantation
KW - Regenerative Medicine/methods
KW - Tissue Culture Techniques/methods
KW - Tissue Scaffolds
M3 - SCORING: Zeitschriftenaufsatz
VL - 42
SP - 329
EP - 336
JO - HANDCHIR MIKROCHIR P
JF - HANDCHIR MIKROCHIR P
SN - 0722-1819
IS - 6
M1 - 6
ER -