Syndecan-1 as a biomarker for sepsis survival after major abdominal surgery

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Syndecan-1 as a biomarker for sepsis survival after major abdominal surgery. / Holzmann, Maximilian S; Winkler, Martin S; Strunden, Mike S; Izbicki, Jakob R; Schoen, Gerhard; Greiwe, Gillis; Pinnschmidt, Hans O; Poppe, Annika; Saugel, Bernd; Daum, Guenter; Goetz, Alwin E; Heckel, Kai.

in: BIOMARK MED, Jahrgang 12, Nr. 2, 02.2018, S. 119-127.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

Harvard

Holzmann, MS, Winkler, MS, Strunden, MS, Izbicki, JR, Schoen, G, Greiwe, G, Pinnschmidt, HO, Poppe, A, Saugel, B, Daum, G, Goetz, AE & Heckel, K 2018, 'Syndecan-1 as a biomarker for sepsis survival after major abdominal surgery', BIOMARK MED, Jg. 12, Nr. 2, S. 119-127. https://doi.org/10.2217/bmm-2017-0231

APA

Holzmann, M. S., Winkler, M. S., Strunden, M. S., Izbicki, J. R., Schoen, G., Greiwe, G., Pinnschmidt, H. O., Poppe, A., Saugel, B., Daum, G., Goetz, A. E., & Heckel, K. (2018). Syndecan-1 as a biomarker for sepsis survival after major abdominal surgery. BIOMARK MED, 12(2), 119-127. https://doi.org/10.2217/bmm-2017-0231

Vancouver

Bibtex

@article{df2ef3c605854f31acaf1308f3497a1d,
title = "Syndecan-1 as a biomarker for sepsis survival after major abdominal surgery",
abstract = "AIM: Sepsis is a serious complication following surgery and identification of patients at risk is of high importance. Syndecan-1 (sSDC1) levels are known to be elevated during sepsis.MATERIALS & METHODS: Fifty-five patients scheduled for major abdominal surgery were prospectively included and sSDC1 concentrations were measured during hospital stay.RESULTS: Patients with postoperative sepsis showed a continued increase of sSDC1 levels and exhibited higher median sSDC1 concentrations at day 1 compared with nonseptic patients 90.3 versus 16.5 ng/ml. A significant association of sSDC1 levels with the incidence of sepsis and death was demonstrated.CONCLUSION: This study identifies sSDC1 as potential biomarker for sepsis and survival after abdominal surgery.",
keywords = "Journal Article",
author = "Holzmann, {Maximilian S} and Winkler, {Martin S} and Strunden, {Mike S} and Izbicki, {Jakob R} and Gerhard Schoen and Gillis Greiwe and Pinnschmidt, {Hans O} and Annika Poppe and Bernd Saugel and Guenter Daum and Goetz, {Alwin E} and Kai Heckel",
year = "2018",
month = feb,
doi = "10.2217/bmm-2017-0231",
language = "English",
volume = "12",
pages = "119--127",
journal = "BIOMARK MED",
issn = "1752-0363",
publisher = "Future Medicine Ltd",
number = "2",

}

RIS

TY - JOUR

T1 - Syndecan-1 as a biomarker for sepsis survival after major abdominal surgery

AU - Holzmann, Maximilian S

AU - Winkler, Martin S

AU - Strunden, Mike S

AU - Izbicki, Jakob R

AU - Schoen, Gerhard

AU - Greiwe, Gillis

AU - Pinnschmidt, Hans O

AU - Poppe, Annika

AU - Saugel, Bernd

AU - Daum, Guenter

AU - Goetz, Alwin E

AU - Heckel, Kai

PY - 2018/2

Y1 - 2018/2

N2 - AIM: Sepsis is a serious complication following surgery and identification of patients at risk is of high importance. Syndecan-1 (sSDC1) levels are known to be elevated during sepsis.MATERIALS & METHODS: Fifty-five patients scheduled for major abdominal surgery were prospectively included and sSDC1 concentrations were measured during hospital stay.RESULTS: Patients with postoperative sepsis showed a continued increase of sSDC1 levels and exhibited higher median sSDC1 concentrations at day 1 compared with nonseptic patients 90.3 versus 16.5 ng/ml. A significant association of sSDC1 levels with the incidence of sepsis and death was demonstrated.CONCLUSION: This study identifies sSDC1 as potential biomarker for sepsis and survival after abdominal surgery.

AB - AIM: Sepsis is a serious complication following surgery and identification of patients at risk is of high importance. Syndecan-1 (sSDC1) levels are known to be elevated during sepsis.MATERIALS & METHODS: Fifty-five patients scheduled for major abdominal surgery were prospectively included and sSDC1 concentrations were measured during hospital stay.RESULTS: Patients with postoperative sepsis showed a continued increase of sSDC1 levels and exhibited higher median sSDC1 concentrations at day 1 compared with nonseptic patients 90.3 versus 16.5 ng/ml. A significant association of sSDC1 levels with the incidence of sepsis and death was demonstrated.CONCLUSION: This study identifies sSDC1 as potential biomarker for sepsis and survival after abdominal surgery.

KW - Journal Article

U2 - 10.2217/bmm-2017-0231

DO - 10.2217/bmm-2017-0231

M3 - SCORING: Journal article

C2 - 29327601

VL - 12

SP - 119

EP - 127

JO - BIOMARK MED

JF - BIOMARK MED

SN - 1752-0363

IS - 2

ER -