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Symptom trajectories in patients with panic disorder in a primary care intervention: Results from a randomized controlled trial (PARADISE)

Standard

Symptom trajectories in patients with panic disorder in a primary care intervention: Results from a randomized controlled trial (PARADISE). / Lukaschek, Karoline; Hiller, Thomas S; Schumacher, Ulrike; Teismann, Tobias; Breitbart, Jörg; Brettschneider, Christian; König, Hans-Helmut; Margraf, Jürgen; Gensichen, Jochen.

in: SCI REP-UK, Jahrgang 9, Nr. 1, 09.05.2019, S. 7170.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Lukaschek, K, Hiller, TS, Schumacher, U, Teismann, T, Breitbart, J, Brettschneider, C, König, H-H, Margraf, J & Gensichen, J 2019, 'Symptom trajectories in patients with panic disorder in a primary care intervention: Results from a randomized controlled trial (PARADISE)', SCI REP-UK, Jg. 9, Nr. 1, S. 7170. https://doi.org/10.1038/s41598-019-43487-x

APA

Lukaschek, K., Hiller, T. S., Schumacher, U., Teismann, T., Breitbart, J., Brettschneider, C., König, H-H., Margraf, J., & Gensichen, J. (2019). Symptom trajectories in patients with panic disorder in a primary care intervention: Results from a randomized controlled trial (PARADISE). SCI REP-UK, 9(1), 7170. https://doi.org/10.1038/s41598-019-43487-x

Vancouver

Lukaschek K, Hiller TS, Schumacher U, Teismann T, Breitbart J, Brettschneider C et al. Symptom trajectories in patients with panic disorder in a primary care intervention: Results from a randomized controlled trial (PARADISE). SCI REP-UK. 2019 Mai 9;9(1):7170. https://doi.org/10.1038/s41598-019-43487-x

Bibtex

@article{d6687d041a3745b1b6266d25a0602e83,
title = "Symptom trajectories in patients with panic disorder in a primary care intervention: Results from a randomized controlled trial (PARADISE)",
abstract = "This analysis aims to identify and characterize symptom trajectories in primary care patients with panic disorder with/without agoraphobia (PD/AG) who participated in a primary care team based training involving elements of cognitive behavioural therapy (CBT). Growth Mixture Modeling was used to identify different latent classes of change in patients with PD/AG (N = 176) who underwent treatment including CBT elements. We identified three patient classes with distinct similar trajectories. Class 1 (n = 58, mean age: 46.2 years ± 13.4 years, 81% women) consisted of patients with an initially high symptom burden, but symptoms declined constantly over the intervention period. Symptoms of patients in class 2 (n = 89, mean age: 44.2 years ± 14.5 years, 67.4% women) declined rapidly at the beginning, then patients went into a plateau-phase. The third class (n = 29, mean age: 47.0 years ± 12.4 years, 65.5% women) was characterized by an unstable course and had the worse outcome. Our findings show that only a minority did not respond to the treatment. To identify this minority and refer to a specialist would help patients to get intensive care in time.",
keywords = "Journal Article",
author = "Karoline Lukaschek and Hiller, {Thomas S} and Ulrike Schumacher and Tobias Teismann and J{\"o}rg Breitbart and Christian Brettschneider and Hans-Helmut K{\"o}nig and J{\"u}rgen Margraf and Jochen Gensichen",
year = "2019",
month = may,
day = "9",
doi = "10.1038/s41598-019-43487-x",
language = "English",
volume = "9",
pages = "7170",
journal = "SCI REP-UK",
issn = "2045-2322",
publisher = "NATURE PUBLISHING GROUP",
number = "1",

}

RIS

TY - JOUR

T1 - Symptom trajectories in patients with panic disorder in a primary care intervention: Results from a randomized controlled trial (PARADISE)

AU - Lukaschek, Karoline

AU - Hiller, Thomas S

AU - Schumacher, Ulrike

AU - Teismann, Tobias

AU - Breitbart, Jörg

AU - Brettschneider, Christian

AU - König, Hans-Helmut

AU - Margraf, Jürgen

AU - Gensichen, Jochen

PY - 2019/5/9

Y1 - 2019/5/9

N2 - This analysis aims to identify and characterize symptom trajectories in primary care patients with panic disorder with/without agoraphobia (PD/AG) who participated in a primary care team based training involving elements of cognitive behavioural therapy (CBT). Growth Mixture Modeling was used to identify different latent classes of change in patients with PD/AG (N = 176) who underwent treatment including CBT elements. We identified three patient classes with distinct similar trajectories. Class 1 (n = 58, mean age: 46.2 years ± 13.4 years, 81% women) consisted of patients with an initially high symptom burden, but symptoms declined constantly over the intervention period. Symptoms of patients in class 2 (n = 89, mean age: 44.2 years ± 14.5 years, 67.4% women) declined rapidly at the beginning, then patients went into a plateau-phase. The third class (n = 29, mean age: 47.0 years ± 12.4 years, 65.5% women) was characterized by an unstable course and had the worse outcome. Our findings show that only a minority did not respond to the treatment. To identify this minority and refer to a specialist would help patients to get intensive care in time.

AB - This analysis aims to identify and characterize symptom trajectories in primary care patients with panic disorder with/without agoraphobia (PD/AG) who participated in a primary care team based training involving elements of cognitive behavioural therapy (CBT). Growth Mixture Modeling was used to identify different latent classes of change in patients with PD/AG (N = 176) who underwent treatment including CBT elements. We identified three patient classes with distinct similar trajectories. Class 1 (n = 58, mean age: 46.2 years ± 13.4 years, 81% women) consisted of patients with an initially high symptom burden, but symptoms declined constantly over the intervention period. Symptoms of patients in class 2 (n = 89, mean age: 44.2 years ± 14.5 years, 67.4% women) declined rapidly at the beginning, then patients went into a plateau-phase. The third class (n = 29, mean age: 47.0 years ± 12.4 years, 65.5% women) was characterized by an unstable course and had the worse outcome. Our findings show that only a minority did not respond to the treatment. To identify this minority and refer to a specialist would help patients to get intensive care in time.

KW - Journal Article

U2 - 10.1038/s41598-019-43487-x

DO - 10.1038/s41598-019-43487-x

M3 - SCORING: Journal article

C2 - 31073189

VL - 9

SP - 7170

JO - SCI REP-UK

JF - SCI REP-UK

SN - 2045-2322

IS - 1

ER -