Symetis ACURATE TAVI: review of the technology, developments and current data with this self-expanding transcatheter heart valve
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Symetis ACURATE TAVI: review of the technology, developments and current data with this self-expanding transcatheter heart valve. / Schäfer, U; Conradi, L; Diemert, P; Deuschl, F; Schofer, N; Seiffert, M; Lubos, E; Schirmer, J; Reichenspurner, H; Blankenberg, S; Treede, H.
in: MINERVA CARDIOANGIOL , Jahrgang 63, Nr. 5, 10.2015, S. 359-369.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung
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T1 - Symetis ACURATE TAVI: review of the technology, developments and current data with this self-expanding transcatheter heart valve
AU - Schäfer, U
AU - Conradi, L
AU - Diemert, P
AU - Deuschl, F
AU - Schofer, N
AU - Seiffert, M
AU - Lubos, E
AU - Schirmer, J
AU - Reichenspurner, H
AU - Blankenberg, S
AU - Treede, H
PY - 2015/10
Y1 - 2015/10
N2 - The Symetis ACURATE TA and ACURATE neo technology is a novel transcatheter heart valve for treatment of aortic valvular stenosis. This review illustrates the implantation steps, which are designed for an easy and intuitive transapical and transfemoral TAVI procedure. The most important difference to other self-expanding platforms is the top-down deployment with minimal protrusion of the stent towards the left ventricular outflow tract. In addition, the supra-annularly placed porcine leaflets provide very low gradients and the pericardial skirt acts very effectively to seal against paravalvular leaks. This review reports about the hemodynamic features, low rates of paravalvular leaks and very low rates of pacemaker implantation, which have been observed in various registries. Meanwhile more than 3000 patients have been treated worldwide and additional registries are currently under investigation.
AB - The Symetis ACURATE TA and ACURATE neo technology is a novel transcatheter heart valve for treatment of aortic valvular stenosis. This review illustrates the implantation steps, which are designed for an easy and intuitive transapical and transfemoral TAVI procedure. The most important difference to other self-expanding platforms is the top-down deployment with minimal protrusion of the stent towards the left ventricular outflow tract. In addition, the supra-annularly placed porcine leaflets provide very low gradients and the pericardial skirt acts very effectively to seal against paravalvular leaks. This review reports about the hemodynamic features, low rates of paravalvular leaks and very low rates of pacemaker implantation, which have been observed in various registries. Meanwhile more than 3000 patients have been treated worldwide and additional registries are currently under investigation.
KW - Animals
KW - Aortic Valve Stenosis/surgery
KW - Heart Valve Prosthesis
KW - Hemodynamics
KW - Humans
KW - Prosthesis Design
KW - Stents
KW - Swine
KW - Transcatheter Aortic Valve Replacement/methods
M3 - SCORING: Review article
C2 - 26198875
VL - 63
SP - 359
EP - 369
JO - MINERVA CARDIOANGIOL
JF - MINERVA CARDIOANGIOL
SN - 0026-4725
IS - 5
ER -