Sustained response after remdesivir and convalescent plasma therapy in a B-cell depleted patient with protracted COVID-19

Jakob Malsy; Luzia Veletzky; Janna Heide; Annette Hennigs; Ines Gil-Ibanez; Alexander Stein; Marc Lütgehetmann; Ulrich Rosien; Dorothea Jasper; Sven Peine; Jens Hiller; Friedrich Haag; Stefan Schmiedel; Samuel Huber; Sabine Jordan; Marylyn M Addo; Julian Schulze Zur Wiesch

doi:10.1093/cid/ciaa1637

Sustained response after remdesivir and convalescent plasma therapy in a B-cell depleted patient with protracted COVID-19

Jakob Malsy (Geteilte/r Erstautor/in)
Luzia Veletzky (Geteilte/r Erstautor/in)
Janna Heide
Annette Hennigs
Ines Gil-Ibanez
Alexander Stein
Marc Lütgehetmann
Ulrich Rosien
Dorothea Jasper
Sven Peine
Jens Hiller
Friedrich Haag
Stefan Schmiedel
Samuel Huber
Sabine Jordan
Marylyn M Addo
Julian Schulze Zur Wiesch

Beteiligte Einrichtungen

Abstract

We provide detailed clinical, virological and immunological data of a B-cell depleted patient treated with obinutuzumab for follicular lymphoma with protracted COVID-19 and viremia. A sustained response was achieved after two courses of remdesivir and subsequent convalescent plasma therapy. Immunocompromised patients might require combined and prolonged antiviral treatment regimens.

Bibliografische Daten

Originalsprache	Englisch
ISSN	1058-4838
DOIs	https://doi.org/10.1093/cid/ciaa1637
Status	Veröffentlicht - 26.10.2020

Anmerkungen des Dekanats

PubMed	33103195