Stammzellbasierte Therapieansätze für retinale Erkrankungen

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Stammzellbasierte Therapieansätze für retinale Erkrankungen. / Bartsch, U; Linke, S J; Petrowitz, B.

in: OPHTHALMOLOGE, Jahrgang 102, Nr. 7, 01.07.2005, S. 679-87.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{ab3f73ab78484f1b97ad5a71f583dde3,
title = "Stammzellbasierte Therapieans{\"a}tze f{\"u}r retinale Erkrankungen",
abstract = "In the context of cell-based therapies for hereditary retinal dystrophies and other retinal disorders, interest has focussed on the therapeutic potential of embryonic and tissue-specific stem cells. Stem cells are characterised by their capacity for self-renewal and by their multipotentiality. Because of these properties, they can be expanded in vitro and eventually differentiated into {"}desired{"} specialized cell types. Stem cells are not only candidate cells for the development of cell replacement strategies, but are also interesting cells for the establishment of ex vivo gene therapies. Here, we discuss recent experimental work performed to evaluate the therapeutic potential of embryonic, mesenchymal, hematopoietic, neural and retinal stem cells for the treatment of inherited retinal dystrophies and other retinal diseases.",
keywords = "Animals, Clinical Trials as Topic, Genetic Therapy, Humans, Physician's Practice Patterns, Practice Guidelines as Topic, Retinal Diseases, Stem Cell Transplantation, Treatment Outcome",
author = "U Bartsch and Linke, {S J} and B Petrowitz",
year = "2005",
month = jul,
day = "1",
doi = "10.1007/s00347-005-1188-4",
language = "Deutsch",
volume = "102",
pages = "679--87",
journal = "OPHTHALMOLOGE",
issn = "0941-293X",
publisher = "Springer",
number = "7",

}

RIS

TY - JOUR

T1 - Stammzellbasierte Therapieansätze für retinale Erkrankungen

AU - Bartsch, U

AU - Linke, S J

AU - Petrowitz, B

PY - 2005/7/1

Y1 - 2005/7/1

N2 - In the context of cell-based therapies for hereditary retinal dystrophies and other retinal disorders, interest has focussed on the therapeutic potential of embryonic and tissue-specific stem cells. Stem cells are characterised by their capacity for self-renewal and by their multipotentiality. Because of these properties, they can be expanded in vitro and eventually differentiated into "desired" specialized cell types. Stem cells are not only candidate cells for the development of cell replacement strategies, but are also interesting cells for the establishment of ex vivo gene therapies. Here, we discuss recent experimental work performed to evaluate the therapeutic potential of embryonic, mesenchymal, hematopoietic, neural and retinal stem cells for the treatment of inherited retinal dystrophies and other retinal diseases.

AB - In the context of cell-based therapies for hereditary retinal dystrophies and other retinal disorders, interest has focussed on the therapeutic potential of embryonic and tissue-specific stem cells. Stem cells are characterised by their capacity for self-renewal and by their multipotentiality. Because of these properties, they can be expanded in vitro and eventually differentiated into "desired" specialized cell types. Stem cells are not only candidate cells for the development of cell replacement strategies, but are also interesting cells for the establishment of ex vivo gene therapies. Here, we discuss recent experimental work performed to evaluate the therapeutic potential of embryonic, mesenchymal, hematopoietic, neural and retinal stem cells for the treatment of inherited retinal dystrophies and other retinal diseases.

KW - Animals

KW - Clinical Trials as Topic

KW - Genetic Therapy

KW - Humans

KW - Physician's Practice Patterns

KW - Practice Guidelines as Topic

KW - Retinal Diseases

KW - Stem Cell Transplantation

KW - Treatment Outcome

U2 - 10.1007/s00347-005-1188-4

DO - 10.1007/s00347-005-1188-4

M3 - SCORING: Zeitschriftenaufsatz

C2 - 15871024

VL - 102

SP - 679

EP - 687

JO - OPHTHALMOLOGE

JF - OPHTHALMOLOGE

SN - 0941-293X

IS - 7

ER -