Spontaneous control of HCV is associated with expression of HLA-B 57 and preservation of targeted epitopes.

  • Arthur Y Kim
  • Thomas Kuntzen
  • Joerg Timm
  • Brian E Nolan
  • Melanie A Baca
  • Laura L Reyor
  • Andrew C Berical
  • Andrea J Feller
  • Kristin L Johnson
  • Julian Schulze Zur Wiesch
  • Gregory K Robbins
  • Raymond T Chung
  • Bruce D Walker
  • Mary Carrington
  • Todd M Allen
  • Georg M Lauer

Beteiligte Einrichtungen

Abstract

HLA class I alleles are linked to spontaneous control of hepatitis C virus (HCV) and human immunodeficiency virus-1, but for HCV the roles of particular alleles and corresponding CD8(+) T-cell responses remain incompletely defined. We aimed to determine the correlations between these alleles and natural outcomes of HCV and determine associated key T-cell responses.

Bibliografische Daten

OriginalspracheDeutsch
Aufsatznummer2
ISSN0016-5085
StatusVeröffentlicht - 2011
pubmed 20875418