Spinocerebellar ataxia type 1, 2, and 3 and restless legs syndrome: striatal dopamine D2 receptor status investigated by [11C]raclopride positron emission tomography.

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Spinocerebellar ataxia type 1, 2, and 3 and restless legs syndrome: striatal dopamine D2 receptor status investigated by [11C]raclopride positron emission tomography. / Reimold, Matthias; Globas, Christoph; Gleichmann, Marc; Schulze, Michael; Gerloff, Christian; Bares, Roland; Machulla, H-J; Bürk, Katrin.

in: MOVEMENT DISORD, Jahrgang 21, Nr. 10, 10, 2006, S. 1667-1673.

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@article{52415135ed4d4a7e932e024c3751b9ed,
title = "Spinocerebellar ataxia type 1, 2, and 3 and restless legs syndrome: striatal dopamine D2 receptor status investigated by [11C]raclopride positron emission tomography.",
abstract = "In spinocerebellar ataxias (SCAs), up to 30% of patients complain of restless legs syndrome (RLS). In primary RLS, a putative role of the dopaminergic system has been postulated. To assess dopaminergic function in SCA1, 2, and 3, dopamine D(2) receptor binding potential (BP) was assessed by [(11)C]raclopride positron emission tomography in 10 SCA patients, 4 of whom suffered from RLS as demonstrated by polysomnography. BP was compared to 9 age-matched control subjects. In 2 SCA patients, striatal BP was clearly reduced (",
author = "Matthias Reimold and Christoph Globas and Marc Gleichmann and Michael Schulze and Christian Gerloff and Roland Bares and H-J Machulla and Katrin B{\"u}rk",
year = "2006",
language = "English",
volume = "21",
pages = "1667--1673",
journal = "MOVEMENT DISORD",
issn = "0885-3185",
publisher = "John Wiley and Sons Inc.",
number = "10",

}

RIS

TY - JOUR

T1 - Spinocerebellar ataxia type 1, 2, and 3 and restless legs syndrome: striatal dopamine D2 receptor status investigated by [11C]raclopride positron emission tomography.

AU - Reimold, Matthias

AU - Globas, Christoph

AU - Gleichmann, Marc

AU - Schulze, Michael

AU - Gerloff, Christian

AU - Bares, Roland

AU - Machulla, H-J

AU - Bürk, Katrin

PY - 2006

Y1 - 2006

N2 - In spinocerebellar ataxias (SCAs), up to 30% of patients complain of restless legs syndrome (RLS). In primary RLS, a putative role of the dopaminergic system has been postulated. To assess dopaminergic function in SCA1, 2, and 3, dopamine D(2) receptor binding potential (BP) was assessed by [(11)C]raclopride positron emission tomography in 10 SCA patients, 4 of whom suffered from RLS as demonstrated by polysomnography. BP was compared to 9 age-matched control subjects. In 2 SCA patients, striatal BP was clearly reduced (

AB - In spinocerebellar ataxias (SCAs), up to 30% of patients complain of restless legs syndrome (RLS). In primary RLS, a putative role of the dopaminergic system has been postulated. To assess dopaminergic function in SCA1, 2, and 3, dopamine D(2) receptor binding potential (BP) was assessed by [(11)C]raclopride positron emission tomography in 10 SCA patients, 4 of whom suffered from RLS as demonstrated by polysomnography. BP was compared to 9 age-matched control subjects. In 2 SCA patients, striatal BP was clearly reduced (

M3 - SCORING: Journal article

VL - 21

SP - 1667

EP - 1673

JO - MOVEMENT DISORD

JF - MOVEMENT DISORD

SN - 0885-3185

IS - 10

M1 - 10

ER -