Specific genomic aberrations in primary colorectal cancer are associated with liver metastases.

Sjoerd C Bruin; Christiaan Klijn; Gerrit-Jan Liefers; Linde M Braaf; Simon Joosse; van Beers; H Eric; Victor J Verwaal; Hans Morreau; Lodewyk F Wessels; van Velthuysen; F Marie-Louise; Rob A E M Tollenaar; Van't Veer; J Laura

doi:10.1186/1471-2407-10-662

Specific genomic aberrations in primary colorectal cancer are associated with liver metastases.

Sjoerd C Bruin
Christiaan Klijn
Gerrit-Jan Liefers
Linde M Braaf
Simon Joosse
van Beers
H Eric
Victor J Verwaal
Hans Morreau
Lodewyk F Wessels
van Velthuysen
F Marie-Louise
Rob A E M Tollenaar
Van't Veer
J Laura

Beteiligte Einrichtungen

Institut für Tumorbiologie

Abstract

Accurate staging of colorectal cancer (CRC) with clinicopathological parameters is important for predicting prognosis and guiding treatment but provides no information about organ site of metastases. Patterns of genomic aberrations in primary colorectal tumors may reveal a chromosomal signature for organ specific metastases.

Bibliografische Daten

Originalsprache	Deutsch
ISSN	1471-2407
DOIs	https://doi.org/10.1186/1471-2407-10-662
Status	Veröffentlicht - 2010

pubmed	21126340