Single-trial EEG-fMRI coupling of the emotional auditory early posterior negativity.

TY - JOUR

T1 - Single-trial EEG-fMRI coupling of the emotional auditory early posterior negativity.

AU - Jaspers-Fayer, Fern

AU - Ertl, Matthias

AU - Leicht, Gregor

AU - Leupelt, Anne

AU - Mulert, Christoph

PY - 2012

Y1 - 2012

N2 - Event-related potential (ERP) studies in the visual domain often report an emotion-evoked early posterior negativity (EPN). Studies in the auditory domain have recently shown a similar component. Little source localization has been done on the visual EPN, and no source localization has been done on the auditory EPN. The aim of the current study was to identify the neural generators of the auditory EPN using EEG-fMRI single-trial coupling. Data were recorded from 19 subjects who completed three auditory choice reaction tasks: (1) a control task using neutral tones; (2) a prosodic emotion task involving the categorization of syllables; and (3) a semantic emotion task involving the categorization of words. The waveforms of the emotion tasks diverged from the neutral task over parietal scalp during a very early time window (132-156 ms) and later during a more traditional EPN time window (252-392 ms). In the EEG-fMRI analyses, the variance of the voltage in the earlier time window was correlated with activity in the medial prefrontal cortex, but only in the word task. In the EEG-fMRI analyses of the traditional EPN time window both emotional tasks covaried with activity in the left superior parietal lobule. Our results support previous parietal cortex source localization findings for the visual EPN, and suggest enhanced selective attention to emotional stimuli during the EPN time window.

AB - Event-related potential (ERP) studies in the visual domain often report an emotion-evoked early posterior negativity (EPN). Studies in the auditory domain have recently shown a similar component. Little source localization has been done on the visual EPN, and no source localization has been done on the auditory EPN. The aim of the current study was to identify the neural generators of the auditory EPN using EEG-fMRI single-trial coupling. Data were recorded from 19 subjects who completed three auditory choice reaction tasks: (1) a control task using neutral tones; (2) a prosodic emotion task involving the categorization of syllables; and (3) a semantic emotion task involving the categorization of words. The waveforms of the emotion tasks diverged from the neutral task over parietal scalp during a very early time window (132-156 ms) and later during a more traditional EPN time window (252-392 ms). In the EEG-fMRI analyses, the variance of the voltage in the earlier time window was correlated with activity in the medial prefrontal cortex, but only in the word task. In the EEG-fMRI analyses of the traditional EPN time window both emotional tasks covaried with activity in the left superior parietal lobule. Our results support previous parietal cortex source localization findings for the visual EPN, and suggest enhanced selective attention to emotional stimuli during the EPN time window.

KW - Humans

KW - Male

KW - Female

KW - Young Adult

KW - Signal Processing, Computer-Assisted

KW - Magnetic Resonance Imaging

KW - Electroencephalography

KW - Brain/physiology

KW - Auditory Perception/physiology

KW - Emotions/physiology

KW - Reaction Time/physiology

KW - Acoustic Stimulation

KW - Brain Mapping/methods

KW - Evoked Potentials, Auditory/physiology

KW - Humans

KW - Male

KW - Female

KW - Young Adult

KW - Signal Processing, Computer-Assisted

KW - Magnetic Resonance Imaging

KW - Electroencephalography

KW - Brain/physiology

KW - Auditory Perception/physiology

KW - Emotions/physiology

KW - Reaction Time/physiology

KW - Acoustic Stimulation

KW - Brain Mapping/methods

KW - Evoked Potentials, Auditory/physiology

M3 - SCORING: Journal article

VL - 62

SP - 1807

EP - 1814

JO - NEUROIMAGE

JF - NEUROIMAGE

SN - 1053-8119

IS - 3

M1 - 3

ER -