Single application of high-intensity focused ultrasound as a first-line therapy for clinically localized prostate cancer: 5-year outcomes.

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Single application of high-intensity focused ultrasound as a first-line therapy for clinically localized prostate cancer: 5-year outcomes. / Pfeiffer, Dietrich; Berger, Jürgen; Gross, Andreas J.

in: BJU INT, Jahrgang 110, Nr. 11, 11, 2012, S. 1702-1707.

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@article{ab48dd37792f4d1d85e7587530e885a7,
title = "Single application of high-intensity focused ultrasound as a first-line therapy for clinically localized prostate cancer: 5-year outcomes.",
abstract = "Study Type--Therapy (case series) Level of Evidence 4. What's known on the subject? and What does the study add? High-intensity focused ultrasound (HIFU) therapy has been proposed for the treatment of localized prostate cancer (PCa) for all risk levels of tumour recurrence. The study adds data on the efficacy of a single HIFU application in the treatment of PCa with different risks of recurrence. Durable cancer control was achieved in 81.7% of patients with low-risk disease, with rates of efficacy declining in intermediate- and high-risk tumours. The data suggest that the principal domain for minimal invasive HIFU should be low-risk disease.",
keywords = "Humans, Male, Aged, Middle Aged, Aged, 80 and over, Treatment Outcome, Retrospective Studies, Kaplan-Meier Estimate, Prostate-Specific Antigen/blood, Prostatectomy/methods/mortality, Prostatic Neoplasms/blood/mortality/pathology/*therapy, Salvage Therapy/methods/mortality, Ultrasound, High-Intensity Focused, Transrectal/*methods/mortality, Humans, Male, Aged, Middle Aged, Aged, 80 and over, Treatment Outcome, Retrospective Studies, Kaplan-Meier Estimate, Prostate-Specific Antigen/blood, Prostatectomy/methods/mortality, Prostatic Neoplasms/blood/mortality/pathology/*therapy, Salvage Therapy/methods/mortality, Ultrasound, High-Intensity Focused, Transrectal/*methods/mortality",
author = "Dietrich Pfeiffer and J{\"u}rgen Berger and Gross, {Andreas J}",
year = "2012",
language = "English",
volume = "110",
pages = "1702--1707",
journal = "BJU INT",
issn = "1464-4096",
publisher = "Wiley-Blackwell",
number = "11",

}

RIS

TY - JOUR

T1 - Single application of high-intensity focused ultrasound as a first-line therapy for clinically localized prostate cancer: 5-year outcomes.

AU - Pfeiffer, Dietrich

AU - Berger, Jürgen

AU - Gross, Andreas J

PY - 2012

Y1 - 2012

N2 - Study Type--Therapy (case series) Level of Evidence 4. What's known on the subject? and What does the study add? High-intensity focused ultrasound (HIFU) therapy has been proposed for the treatment of localized prostate cancer (PCa) for all risk levels of tumour recurrence. The study adds data on the efficacy of a single HIFU application in the treatment of PCa with different risks of recurrence. Durable cancer control was achieved in 81.7% of patients with low-risk disease, with rates of efficacy declining in intermediate- and high-risk tumours. The data suggest that the principal domain for minimal invasive HIFU should be low-risk disease.

AB - Study Type--Therapy (case series) Level of Evidence 4. What's known on the subject? and What does the study add? High-intensity focused ultrasound (HIFU) therapy has been proposed for the treatment of localized prostate cancer (PCa) for all risk levels of tumour recurrence. The study adds data on the efficacy of a single HIFU application in the treatment of PCa with different risks of recurrence. Durable cancer control was achieved in 81.7% of patients with low-risk disease, with rates of efficacy declining in intermediate- and high-risk tumours. The data suggest that the principal domain for minimal invasive HIFU should be low-risk disease.

KW - Humans

KW - Male

KW - Aged

KW - Middle Aged

KW - Aged, 80 and over

KW - Treatment Outcome

KW - Retrospective Studies

KW - Kaplan-Meier Estimate

KW - Prostate-Specific Antigen/blood

KW - Prostatectomy/methods/mortality

KW - Prostatic Neoplasms/blood/mortality/pathology/therapy

KW - Salvage Therapy/methods/mortality

KW - Ultrasound, High-Intensity Focused, Transrectal/methods/mortality

KW - Humans

KW - Male

KW - Aged

KW - Middle Aged

KW - Aged, 80 and over

KW - Treatment Outcome

KW - Retrospective Studies

KW - Kaplan-Meier Estimate

KW - Prostate-Specific Antigen/blood

KW - Prostatectomy/methods/mortality

KW - Prostatic Neoplasms/blood/mortality/pathology/therapy

KW - Salvage Therapy/methods/mortality

KW - Ultrasound, High-Intensity Focused, Transrectal/methods/mortality

M3 - SCORING: Journal article

VL - 110

SP - 1702

EP - 1707

JO - BJU INT

JF - BJU INT

SN - 1464-4096

IS - 11

M1 - 11

ER -