Single application of high-intensity focused ultrasound as a first-line therapy for clinically localized prostate cancer: 5-year outcomes.
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Single application of high-intensity focused ultrasound as a first-line therapy for clinically localized prostate cancer: 5-year outcomes. / Pfeiffer, Dietrich; Berger, Jürgen; Gross, Andreas J.
in: BJU INT, Jahrgang 110, Nr. 11, 11, 2012, S. 1702-1707.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Single application of high-intensity focused ultrasound as a first-line therapy for clinically localized prostate cancer: 5-year outcomes.
AU - Pfeiffer, Dietrich
AU - Berger, Jürgen
AU - Gross, Andreas J
PY - 2012
Y1 - 2012
N2 - Study Type--Therapy (case series) Level of Evidence 4. What's known on the subject? and What does the study add? High-intensity focused ultrasound (HIFU) therapy has been proposed for the treatment of localized prostate cancer (PCa) for all risk levels of tumour recurrence. The study adds data on the efficacy of a single HIFU application in the treatment of PCa with different risks of recurrence. Durable cancer control was achieved in 81.7% of patients with low-risk disease, with rates of efficacy declining in intermediate- and high-risk tumours. The data suggest that the principal domain for minimal invasive HIFU should be low-risk disease.
AB - Study Type--Therapy (case series) Level of Evidence 4. What's known on the subject? and What does the study add? High-intensity focused ultrasound (HIFU) therapy has been proposed for the treatment of localized prostate cancer (PCa) for all risk levels of tumour recurrence. The study adds data on the efficacy of a single HIFU application in the treatment of PCa with different risks of recurrence. Durable cancer control was achieved in 81.7% of patients with low-risk disease, with rates of efficacy declining in intermediate- and high-risk tumours. The data suggest that the principal domain for minimal invasive HIFU should be low-risk disease.
KW - Humans
KW - Male
KW - Aged
KW - Middle Aged
KW - Aged, 80 and over
KW - Treatment Outcome
KW - Retrospective Studies
KW - Kaplan-Meier Estimate
KW - Prostate-Specific Antigen/blood
KW - Prostatectomy/methods/mortality
KW - Prostatic Neoplasms/blood/mortality/pathology/therapy
KW - Salvage Therapy/methods/mortality
KW - Ultrasound, High-Intensity Focused, Transrectal/methods/mortality
KW - Humans
KW - Male
KW - Aged
KW - Middle Aged
KW - Aged, 80 and over
KW - Treatment Outcome
KW - Retrospective Studies
KW - Kaplan-Meier Estimate
KW - Prostate-Specific Antigen/blood
KW - Prostatectomy/methods/mortality
KW - Prostatic Neoplasms/blood/mortality/pathology/therapy
KW - Salvage Therapy/methods/mortality
KW - Ultrasound, High-Intensity Focused, Transrectal/methods/mortality
M3 - SCORING: Journal article
VL - 110
SP - 1702
EP - 1707
JO - BJU INT
JF - BJU INT
SN - 1464-4096
IS - 11
M1 - 11
ER -