PortalPublikationenSimple Targeted Assays for Metabolic Pathways and Signaling:...

Simple Targeted Assays for Metabolic Pathways and Signaling: A Powerful Tool for Targeted Proteomics

Standard

Simple Targeted Assays for Metabolic Pathways and Signaling: A Powerful Tool for Targeted Proteomics. / Kopczynski, Dominik; Hentschel, Andreas; Coman, Cristina; Schebb, Nils Helge; Hornemann, Thorsten; Mashek, Douglas G; Hartung, Nicole M; Shevchuk, Olga; Schött, Hans-Frieder; Lorenz, Kristina; Torta, Federico; Burla, Bo; Zahedi, René P; Sickmann, Albert; Kreutz, Michael R; Ejsing, Christer S; Medenbach, Jan; Ahrends, Robert.

in: ANAL CHEM, Jahrgang 92, Nr. 20, 20.10.2020, S. 13672-13676.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Kopczynski, D, Hentschel, A, Coman, C, Schebb, NH, Hornemann, T, Mashek, DG, Hartung, NM, Shevchuk, O, Schött, H-F, Lorenz, K, Torta, F, Burla, B, Zahedi, RP, Sickmann, A, Kreutz, MR, Ejsing, CS, Medenbach, J & Ahrends, R 2020, 'Simple Targeted Assays for Metabolic Pathways and Signaling: A Powerful Tool for Targeted Proteomics', ANAL CHEM, Jg. 92, Nr. 20, S. 13672-13676. https://doi.org/10.1021/acs.analchem.0c02793

APA

Kopczynski, D., Hentschel, A., Coman, C., Schebb, N. H., Hornemann, T., Mashek, D. G., Hartung, N. M., Shevchuk, O., Schött, H-F., Lorenz, K., Torta, F., Burla, B., Zahedi, R. P., Sickmann, A., Kreutz, M. R., Ejsing, C. S., Medenbach, J., & Ahrends, R. (2020). Simple Targeted Assays for Metabolic Pathways and Signaling: A Powerful Tool for Targeted Proteomics. ANAL CHEM, 92(20), 13672-13676. https://doi.org/10.1021/acs.analchem.0c02793

Vancouver

Kopczynski D, Hentschel A, Coman C, Schebb NH, Hornemann T, Mashek DG et al. Simple Targeted Assays for Metabolic Pathways and Signaling: A Powerful Tool for Targeted Proteomics. ANAL CHEM. 2020 Okt 20;92(20):13672-13676. https://doi.org/10.1021/acs.analchem.0c02793

Bibtex

@article{a83073cddee04e94a95e389c77ae8f27,
title = "Simple Targeted Assays for Metabolic Pathways and Signaling: A Powerful Tool for Targeted Proteomics",
abstract = "We introduce STAMPS, a pathway-centric web service for the development of targeted proteomics assays. STAMPS guides the user by providing several intuitive interfaces for a rapid and simplified method design. Applying our curated framework to signaling and metabolic pathways, we reduced the average assay development time by a factor of ∼150 and revealed that the insulin signaling is actively controlled by protein abundance changes in insulin-sensitive and -resistance states. Although at the current state STAMPS primarily contains mouse data, it was designed for easy extension with additional organisms.",
author = "Dominik Kopczynski and Andreas Hentschel and Cristina Coman and Schebb, {Nils Helge} and Thorsten Hornemann and Mashek, {Douglas G} and Hartung, {Nicole M} and Olga Shevchuk and Hans-Frieder Sch{\"o}tt and Kristina Lorenz and Federico Torta and Bo Burla and Zahedi, {Ren{\'e} P} and Albert Sickmann and Kreutz, {Michael R} and Ejsing, {Christer S} and Jan Medenbach and Robert Ahrends",
year = "2020",
month = oct,
day = "20",
doi = "10.1021/acs.analchem.0c02793",
language = "English",
volume = "92",
pages = "13672--13676",
journal = "ANAL CHEM",
issn = "0003-2700",
publisher = "American Chemical Society",
number = "20",

}

RIS

TY - JOUR

T1 - Simple Targeted Assays for Metabolic Pathways and Signaling: A Powerful Tool for Targeted Proteomics

AU - Kopczynski, Dominik

AU - Hentschel, Andreas

AU - Coman, Cristina

AU - Schebb, Nils Helge

AU - Hornemann, Thorsten

AU - Mashek, Douglas G

AU - Hartung, Nicole M

AU - Shevchuk, Olga

AU - Schött, Hans-Frieder

AU - Lorenz, Kristina

AU - Torta, Federico

AU - Burla, Bo

AU - Zahedi, René P

AU - Sickmann, Albert

AU - Kreutz, Michael R

AU - Ejsing, Christer S

AU - Medenbach, Jan

AU - Ahrends, Robert

PY - 2020/10/20

Y1 - 2020/10/20

N2 - We introduce STAMPS, a pathway-centric web service for the development of targeted proteomics assays. STAMPS guides the user by providing several intuitive interfaces for a rapid and simplified method design. Applying our curated framework to signaling and metabolic pathways, we reduced the average assay development time by a factor of ∼150 and revealed that the insulin signaling is actively controlled by protein abundance changes in insulin-sensitive and -resistance states. Although at the current state STAMPS primarily contains mouse data, it was designed for easy extension with additional organisms.

AB - We introduce STAMPS, a pathway-centric web service for the development of targeted proteomics assays. STAMPS guides the user by providing several intuitive interfaces for a rapid and simplified method design. Applying our curated framework to signaling and metabolic pathways, we reduced the average assay development time by a factor of ∼150 and revealed that the insulin signaling is actively controlled by protein abundance changes in insulin-sensitive and -resistance states. Although at the current state STAMPS primarily contains mouse data, it was designed for easy extension with additional organisms.

U2 - 10.1021/acs.analchem.0c02793

DO - 10.1021/acs.analchem.0c02793

M3 - SCORING: Journal article

C2 - 32865986

VL - 92

SP - 13672

EP - 13676

JO - ANAL CHEM

JF - ANAL CHEM

SN - 0003-2700

IS - 20

ER -