Short-term versus long-term antiarrhythmic drug treatment after cardioversion of atrial fibrillation (Flec-SL): a prospective, randomised, open-label, blinded endpoint assessment trial.
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Short-term versus long-term antiarrhythmic drug treatment after cardioversion of atrial fibrillation (Flec-SL): a prospective, randomised, open-label, blinded endpoint assessment trial. / Kirchhof, Paulus; Andresen, Dietrich; Bosch, Ralph; Borggrefe, Martin; Meinertz, Thomas; Parade, Ulli; Ravens, Ursula; Samol, Alexander; Steinbeck, Gerhard; Treszl, András; Wegscheider, Karl; Breithardt, Günter.
in: LANCET, Jahrgang 380, Nr. 9838, 9838, 2012, S. 238-246.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Short-term versus long-term antiarrhythmic drug treatment after cardioversion of atrial fibrillation (Flec-SL): a prospective, randomised, open-label, blinded endpoint assessment trial.
AU - Kirchhof, Paulus
AU - Andresen, Dietrich
AU - Bosch, Ralph
AU - Borggrefe, Martin
AU - Meinertz, Thomas
AU - Parade, Ulli
AU - Ravens, Ursula
AU - Samol, Alexander
AU - Steinbeck, Gerhard
AU - Treszl, András
AU - Wegscheider, Karl
AU - Breithardt, Günter
PY - 2012
Y1 - 2012
N2 - Antiarrhythmic drugs prolong the atrial action potential and refractory period, and thereby prevent recurrent atrial fibrillation after cardioversion. The atrial action potential normalises after 2-4 weeks of sinus rhythm, suggesting that antiarrhythmic drugs might not be needed beyond that period. Therefore, we investigated whether short-term antiarrhythmic drug treatment after cardioversion is non-inferior to long-term treatment.
AB - Antiarrhythmic drugs prolong the atrial action potential and refractory period, and thereby prevent recurrent atrial fibrillation after cardioversion. The atrial action potential normalises after 2-4 weeks of sinus rhythm, suggesting that antiarrhythmic drugs might not be needed beyond that period. Therefore, we investigated whether short-term antiarrhythmic drug treatment after cardioversion is non-inferior to long-term treatment.
M3 - SCORING: Journal article
VL - 380
SP - 238
EP - 246
JO - LANCET
JF - LANCET
SN - 0140-6736
IS - 9838
M1 - 9838
ER -