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Short-term application of dexamethasone enhances bone morphogenetic protein-7-induced ectopic bone formation in vivo.

Standard

Short-term application of dexamethasone enhances bone morphogenetic protein-7-induced ectopic bone formation in vivo. / Spiro, Alexander Simon; Beil, F Timo; Schinke, Thorsten; Schilling, Arndt F; Eulenburg, Christine; Rueger, Johannes Maria; Amling, Michael.

in: J TRAUMA, Jahrgang 69, Nr. 6, 6, 2010, S. 1473-1480.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Spiro, AS, Beil, FT, Schinke, T, Schilling, AF, Eulenburg, C, Rueger, JM & Amling, M 2010, 'Short-term application of dexamethasone enhances bone morphogenetic protein-7-induced ectopic bone formation in vivo.', J TRAUMA, Jg. 69, Nr. 6, 6, S. 1473-1480.

APA

Spiro, A. S., Beil, F. T., Schinke, T., Schilling, A. F., Eulenburg, C., Rueger, J. M., & Amling, M. (2010). Short-term application of dexamethasone enhances bone morphogenetic protein-7-induced ectopic bone formation in vivo. J TRAUMA, 69(6), 1473-1480. [6].

Vancouver

Spiro AS, Beil FT, Schinke T, Schilling AF, Eulenburg C, Rueger JM et al. Short-term application of dexamethasone enhances bone morphogenetic protein-7-induced ectopic bone formation in vivo. J TRAUMA. 2010;69(6):1473-1480. 6.

Bibtex

@article{30a4bf1be8c24bbcbdd36b9009ad4d1d,
title = "Short-term application of dexamethasone enhances bone morphogenetic protein-7-induced ectopic bone formation in vivo.",
abstract = "Long-term administration of glucocorticoids may lead to bone loss and osteoporosis as reported in previous experimental and clinical studies. On the other hand, several in vitro studies have demonstrated that dexamethasone treatment induces proliferation and differentiation of human and murine osteoblast precursors. Thereby, a positive interaction of dexamethasone with the osteoinductive bone morphogenetic proteins (BMPs) is reported in vitro, but in vivo studies are still missing. Thus, the aim of this study was to determine whether short-term application of dexamethasone may improve BMP-7-induced bone formation in vivo.",
author = "Spiro, {Alexander Simon} and Beil, {F Timo} and Thorsten Schinke and Schilling, {Arndt F} and Christine Eulenburg and Rueger, {Johannes Maria} and Michael Amling",
year = "2010",
language = "Deutsch",
volume = "69",
pages = "1473--1480",
number = "6",

}

RIS

TY - JOUR

T1 - Short-term application of dexamethasone enhances bone morphogenetic protein-7-induced ectopic bone formation in vivo.

AU - Spiro, Alexander Simon

AU - Beil, F Timo

AU - Schinke, Thorsten

AU - Schilling, Arndt F

AU - Eulenburg, Christine

AU - Rueger, Johannes Maria

AU - Amling, Michael

PY - 2010

Y1 - 2010

N2 - Long-term administration of glucocorticoids may lead to bone loss and osteoporosis as reported in previous experimental and clinical studies. On the other hand, several in vitro studies have demonstrated that dexamethasone treatment induces proliferation and differentiation of human and murine osteoblast precursors. Thereby, a positive interaction of dexamethasone with the osteoinductive bone morphogenetic proteins (BMPs) is reported in vitro, but in vivo studies are still missing. Thus, the aim of this study was to determine whether short-term application of dexamethasone may improve BMP-7-induced bone formation in vivo.

AB - Long-term administration of glucocorticoids may lead to bone loss and osteoporosis as reported in previous experimental and clinical studies. On the other hand, several in vitro studies have demonstrated that dexamethasone treatment induces proliferation and differentiation of human and murine osteoblast precursors. Thereby, a positive interaction of dexamethasone with the osteoinductive bone morphogenetic proteins (BMPs) is reported in vitro, but in vivo studies are still missing. Thus, the aim of this study was to determine whether short-term application of dexamethasone may improve BMP-7-induced bone formation in vivo.

M3 - SCORING: Zeitschriftenaufsatz

VL - 69

SP - 1473

EP - 1480

IS - 6

M1 - 6

ER -