Serial testing with an interferon- release assay in German healthcare workers.
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Serial testing with an interferon- release assay in German healthcare workers. / Schablon, Anja; Harling, Melanie; Diel, Roland; Ringshausen, Felix C; Jose, Torres Costa; Nienhaus, Albert.
in: GMS Krankenhhyg Interdiszip, Jahrgang 5, Nr. 2, 2, 2010.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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T1 - Serial testing with an interferon- release assay in German healthcare workers.
AU - Schablon, Anja
AU - Harling, Melanie
AU - Diel, Roland
AU - Ringshausen, Felix C
AU - Jose, Torres Costa
AU - Nienhaus, Albert
PY - 2010
Y1 - 2010
N2 - Aim: Data concerning conversion and reversion rates in the serial testing of healthcare workers (HCWs) is rare. So far, there is no consensus on how to define and interpret interferon-gamma release assays (IGRA) conversions and reversions, or how to deal with such results. We analysed conversion and reversion rates in the serial testing of HCWs using an IGRA.Methods: The study population comprises 287 HCWs, who participated in routine occupational safety and health screening for latent tuberculosis infection (LTBI) with the QuantiFERON-TB(®) Gold In-Tube assay (QFT). Four different definitions for conversion and reversion were applied: 1) transgression or regression above/below the cut-off; 2) increase from 0.7 IU/ml or decrease from >0.7 to
AB - Aim: Data concerning conversion and reversion rates in the serial testing of healthcare workers (HCWs) is rare. So far, there is no consensus on how to define and interpret interferon-gamma release assays (IGRA) conversions and reversions, or how to deal with such results. We analysed conversion and reversion rates in the serial testing of HCWs using an IGRA.Methods: The study population comprises 287 HCWs, who participated in routine occupational safety and health screening for latent tuberculosis infection (LTBI) with the QuantiFERON-TB(®) Gold In-Tube assay (QFT). Four different definitions for conversion and reversion were applied: 1) transgression or regression above/below the cut-off; 2) increase from 0.7 IU/ml or decrease from >0.7 to
M3 - SCORING: Zeitschriftenaufsatz
VL - 5
IS - 2
M1 - 2
ER -