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Sequencing data of the antiglioma antibody MUC 2-63 and strategy for construction of chimeric antibodies

Standard

Sequencing data of the antiglioma antibody MUC 2-63 and strategy for construction of chimeric antibodies. / Hagel, C; Neumaier, M; Stavrou, D.

in: Cell biophysics, Jahrgang 24-25, 01.01.1994, S. 331-9.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Hagel, C, Neumaier, M & Stavrou, D 1994, 'Sequencing data of the antiglioma antibody MUC 2-63 and strategy for construction of chimeric antibodies', Cell biophysics, Jg. 24-25, S. 331-9.

APA

Hagel, C., Neumaier, M., & Stavrou, D. (1994). Sequencing data of the antiglioma antibody MUC 2-63 and strategy for construction of chimeric antibodies. Cell biophysics, 24-25, 331-9.

Vancouver

Hagel C, Neumaier M, Stavrou D. Sequencing data of the antiglioma antibody MUC 2-63 and strategy for construction of chimeric antibodies. Cell biophysics. 1994 Jan 1;24-25:331-9.

Bibtex

@article{bfaed7e7dfb04fefade87de36f7f0d4f,
title = "Sequencing data of the antiglioma antibody MUC 2-63 and strategy for construction of chimeric antibodies",
abstract = "The murine monoclonal antibody MUC 2-63 detects a surface antigen expressed in human gliomas as demonstrated by means of immunohistochemistry and Western blot. In addition, MUC 2-63 has been successfully used in vivo for radioimaging in nude mice bearing glioma xenografts and in glioma patients. The genes coding for the variable regions of MUC 2-63 were isolated for construction of antibody derivatives with reduced immunogenic effects and of reduced size. DNA and protein sequencing data and strategy for construction of chimeric antibodies and single-chain Fv fragments are presented.",
keywords = "Amino Acid Sequence, Animals, Antibodies, Monoclonal, Base Sequence, Cloning, Molecular, Genetic Code, Glioma, Humans, Immunoglobulin Variable Region, Mice, Molecular Sequence Data, Protein Engineering, Recombinant Fusion Proteins",
author = "C Hagel and M Neumaier and D Stavrou",
year = "1994",
month = jan,
day = "1",
language = "English",
volume = "24-25",
pages = "331--9",

}

RIS

TY - JOUR

T1 - Sequencing data of the antiglioma antibody MUC 2-63 and strategy for construction of chimeric antibodies

AU - Hagel, C

AU - Neumaier, M

AU - Stavrou, D

PY - 1994/1/1

Y1 - 1994/1/1

N2 - The murine monoclonal antibody MUC 2-63 detects a surface antigen expressed in human gliomas as demonstrated by means of immunohistochemistry and Western blot. In addition, MUC 2-63 has been successfully used in vivo for radioimaging in nude mice bearing glioma xenografts and in glioma patients. The genes coding for the variable regions of MUC 2-63 were isolated for construction of antibody derivatives with reduced immunogenic effects and of reduced size. DNA and protein sequencing data and strategy for construction of chimeric antibodies and single-chain Fv fragments are presented.

AB - The murine monoclonal antibody MUC 2-63 detects a surface antigen expressed in human gliomas as demonstrated by means of immunohistochemistry and Western blot. In addition, MUC 2-63 has been successfully used in vivo for radioimaging in nude mice bearing glioma xenografts and in glioma patients. The genes coding for the variable regions of MUC 2-63 were isolated for construction of antibody derivatives with reduced immunogenic effects and of reduced size. DNA and protein sequencing data and strategy for construction of chimeric antibodies and single-chain Fv fragments are presented.

KW - Amino Acid Sequence

KW - Animals

KW - Antibodies, Monoclonal

KW - Base Sequence

KW - Cloning, Molecular

KW - Genetic Code

KW - Glioma

KW - Humans

KW - Immunoglobulin Variable Region

KW - Mice

KW - Molecular Sequence Data

KW - Protein Engineering

KW - Recombinant Fusion Proteins

M3 - SCORING: Journal article

C2 - 7736538

VL - 24-25

SP - 331

EP - 339

ER -