Screening for cerebellopontine angle tumors: is a CISS sufficient?
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Screening for cerebellopontine angle tumors: is a CISS sufficient? / Goebell, Einar; Ries, Thorsten; Kucinski, Thomas; Grzyska, Ullrich; Eckert, Bernd; Fiehler, Jens; Eickhoff, Britta; Regelsberger, Jan; Koch, Christoph; Zeumer, Hermann.
in: EUR RADIOL, Jahrgang 15, Nr. 2, 2, 2005, S. 286-291.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Screening for cerebellopontine angle tumors: is a CISS sufficient?
AU - Goebell, Einar
AU - Ries, Thorsten
AU - Kucinski, Thomas
AU - Grzyska, Ullrich
AU - Eckert, Bernd
AU - Fiehler, Jens
AU - Eickhoff, Britta
AU - Regelsberger, Jan
AU - Koch, Christoph
AU - Zeumer, Hermann
PY - 2005
Y1 - 2005
N2 - This study attempted to evaluate the reliability of ultra-thin T2-weighted imaging with a constructive interference in steady state (CISS) sequence as a screening method for tumors in the cerebellopontine angle. A retrospective study of 200 CISS examinations was made by five investigators. The examinations were inspected on plain film supported by clinical information. The interobserver agreement in the detection of lesions was analyzed. Fourteen cases (50% of the contrast-enhancing lesions) were rated pathological by all five readers. One case of subarachnoid lymphoma infiltration was overlooked by all five readers. Overall, six pathological lesions (median = 6, range 1-9) were not identified. The interobserver agreement for all pathological lesions was moderate (kappa=0.53; 95% CI, 0.43-0.62). The mean sensitivity was 77.8% (range 72.0-96.3%), and the mean specificity was 97.6% (range 94.8-100%). The median sensitivity for pathological lesions concerning only patients with acute sensorineural hearing loss (n=148, patients with 20 contrast-enhancing cases) was 86.6% (range 80-100%), and median specificity was 95.2% (range 84.4-96.9%) with a moderate interobserver agreement (kappa=0.55; 95% CI, 0.44-0.66). In our opinion the CISS sequence is a valuable addition to the examination of the cerebellopontine angle but lacks sufficient reliability for the detection of tumors of small size or of tumors adjacent to brain parenchyma or the temporal bone.
AB - This study attempted to evaluate the reliability of ultra-thin T2-weighted imaging with a constructive interference in steady state (CISS) sequence as a screening method for tumors in the cerebellopontine angle. A retrospective study of 200 CISS examinations was made by five investigators. The examinations were inspected on plain film supported by clinical information. The interobserver agreement in the detection of lesions was analyzed. Fourteen cases (50% of the contrast-enhancing lesions) were rated pathological by all five readers. One case of subarachnoid lymphoma infiltration was overlooked by all five readers. Overall, six pathological lesions (median = 6, range 1-9) were not identified. The interobserver agreement for all pathological lesions was moderate (kappa=0.53; 95% CI, 0.43-0.62). The mean sensitivity was 77.8% (range 72.0-96.3%), and the mean specificity was 97.6% (range 94.8-100%). The median sensitivity for pathological lesions concerning only patients with acute sensorineural hearing loss (n=148, patients with 20 contrast-enhancing cases) was 86.6% (range 80-100%), and median specificity was 95.2% (range 84.4-96.9%) with a moderate interobserver agreement (kappa=0.55; 95% CI, 0.44-0.66). In our opinion the CISS sequence is a valuable addition to the examination of the cerebellopontine angle but lacks sufficient reliability for the detection of tumors of small size or of tumors adjacent to brain parenchyma or the temporal bone.
M3 - SCORING: Zeitschriftenaufsatz
VL - 15
SP - 286
EP - 291
JO - EUR RADIOL
JF - EUR RADIOL
SN - 0938-7994
IS - 2
M1 - 2
ER -
