Schwerste kontaktlinsenassoziierte mykotische Keratitis
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Schwerste kontaktlinsenassoziierte mykotische Keratitis. / Eddy, M-T; Steinberg, J; Richard, G; Hassenstein, A.
in: OPHTHALMOLOGE, Jahrgang 109, Nr. 11, 01.11.2012, S. 1106-11.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Schwerste kontaktlinsenassoziierte mykotische Keratitis
AU - Eddy, M-T
AU - Steinberg, J
AU - Richard, G
AU - Hassenstein, A
PY - 2012/11/1
Y1 - 2012/11/1
N2 - A 23-year-old man presented with severe contact lens-associated keratitis and descemetocele with pre-existing drug therapy. After 1 week of intensive antibiotic treatment Aspergillus fumigatus was identified. Despite adjusted antimycotic treatment a corneal perforation occurred. Due to peripheral scleral infiltration the cornea was primarily closed with a double layer amniotic membrane in order to avoid a sclerokeratoplasty with a bad prognosis. After 2 weeks the peripheral corneal situation stabilized and a simple keratoplasty á chaud could be performed. After surgery and adjusted drug therapy, no adequate signs of recovery occured. In repeated microbiological testing an additional Candida albicans infection was diagnosed and therapy was readjusted. This resulted in a cure of the corneal infection. After 5 years and a re-keratoplasty the patient presented with a clear corneal transplant and a corrected visual acuity of 20/25.
AB - A 23-year-old man presented with severe contact lens-associated keratitis and descemetocele with pre-existing drug therapy. After 1 week of intensive antibiotic treatment Aspergillus fumigatus was identified. Despite adjusted antimycotic treatment a corneal perforation occurred. Due to peripheral scleral infiltration the cornea was primarily closed with a double layer amniotic membrane in order to avoid a sclerokeratoplasty with a bad prognosis. After 2 weeks the peripheral corneal situation stabilized and a simple keratoplasty á chaud could be performed. After surgery and adjusted drug therapy, no adequate signs of recovery occured. In repeated microbiological testing an additional Candida albicans infection was diagnosed and therapy was readjusted. This resulted in a cure of the corneal infection. After 5 years and a re-keratoplasty the patient presented with a clear corneal transplant and a corrected visual acuity of 20/25.
KW - Antifungal Agents
KW - Aspergillosis
KW - Candidiasis
KW - Combined Modality Therapy
KW - Contact Lenses
KW - Corneal Transplantation
KW - Eye Infections, Fungal
KW - Humans
KW - Keratitis
KW - Male
KW - Treatment Outcome
KW - Young Adult
U2 - 10.1007/s00347-012-2570-7
DO - 10.1007/s00347-012-2570-7
M3 - SCORING: Zeitschriftenaufsatz
C2 - 22940808
VL - 109
SP - 1106
EP - 1111
JO - OPHTHALMOLOGE
JF - OPHTHALMOLOGE
SN - 0941-293X
IS - 11
ER -