Sample Preparation for Time-Resolved Serial Crystallography
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Sample Preparation for Time-Resolved Serial Crystallography : Practical Considerations. / Mehrabi, Pedram; Schulz, Eike C.
Advanced Methods in Structural Biology. Hrsg. / Ângela Sousa; Luis Passarinha. 1. Aufl. New York, NY : Humana Press, 2023. S. 361-379 (Methods Mol Biol; Band 2652).Publikationen: SCORING: Beitrag in Buch/Sammelwerk › SCORING: Beitrag in Sammelwerk › Forschung › Begutachtung
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TY - CHAP
T1 - Sample Preparation for Time-Resolved Serial Crystallography
T2 - Practical Considerations
AU - Mehrabi, Pedram
AU - Schulz, Eike C
N1 - © 2023. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2023
Y1 - 2023
N2 - Time-resolved serial crystallography is an emerging method to elucidate the structure-function relationship of biomolecular systems at up to atomic resolution. However, to make this demanding method a success, a number of experimental requirements have to be met. In this chapter, we summarize general guidelines and protocols towards performing time-resolved crystallography experiments, with a particular emphasis on sample requirements and preparation but also a brief excursion into reaction initiation.
AB - Time-resolved serial crystallography is an emerging method to elucidate the structure-function relationship of biomolecular systems at up to atomic resolution. However, to make this demanding method a success, a number of experimental requirements have to be met. In this chapter, we summarize general guidelines and protocols towards performing time-resolved crystallography experiments, with a particular emphasis on sample requirements and preparation but also a brief excursion into reaction initiation.
KW - Crystallography/methods
KW - Time Factors
KW - Specimen Handling
KW - Crystallography, X-Ray
U2 - 10.1007/978-1-0716-3147-8_21
DO - 10.1007/978-1-0716-3147-8_21
M3 - SCORING: Contribution to collected editions/anthologies
C2 - 37093487
SN - 978-1-0716-3146-1
SN - 978-1-0716-3149-2
T3 - Methods Mol Biol
SP - 361
EP - 379
BT - Advanced Methods in Structural Biology
A2 - Sousa, Ângela
A2 - Passarinha, Luis
PB - Humana Press
CY - New York, NY
ER -