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Safety and efficacy of aneurysm treatment with WEB in the cumulative population of three prospective, multicenter series

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Safety and efficacy of aneurysm treatment with WEB in the cumulative population of three prospective, multicenter series. / Pierot, Laurent; Moret, Jacques; Barreau, Xavier; Szikora, Istvan; Herbreteau, Denis; Turjman, Francis; Holtmannspötter, Markus; Januel, Anne-Christine; Costalat, Vincent; Fiehler, Jens; Klisch, Joachim; Gauvrit, Jean-Yves; Weber, Werner; Desal, Hubert; Velasco, Stéphane; Liebig, Thomas; Stockx, Luc; Berkefeld, Joachim; Molyneux, Andrew; Byrne, James; Spelle, Laurent.

in: J NEUROINTERV SURG, Jahrgang 10, Nr. 6, 06.2018, S. 553-559.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Pierot, L, Moret, J, Barreau, X, Szikora, I, Herbreteau, D, Turjman, F, Holtmannspötter, M, Januel, A-C, Costalat, V, Fiehler, J, Klisch, J, Gauvrit, J-Y, Weber, W, Desal, H, Velasco, S, Liebig, T, Stockx, L, Berkefeld, J, Molyneux, A, Byrne, J & Spelle, L 2018, 'Safety and efficacy of aneurysm treatment with WEB in the cumulative population of three prospective, multicenter series', J NEUROINTERV SURG, Jg. 10, Nr. 6, S. 553-559. https://doi.org/10.1136/neurintsurg-2017-013448

APA

Pierot, L., Moret, J., Barreau, X., Szikora, I., Herbreteau, D., Turjman, F., Holtmannspötter, M., Januel, A-C., Costalat, V., Fiehler, J., Klisch, J., Gauvrit, J-Y., Weber, W., Desal, H., Velasco, S., Liebig, T., Stockx, L., Berkefeld, J., Molyneux, A., ... Spelle, L. (2018). Safety and efficacy of aneurysm treatment with WEB in the cumulative population of three prospective, multicenter series. J NEUROINTERV SURG, 10(6), 553-559. https://doi.org/10.1136/neurintsurg-2017-013448

Vancouver

Pierot L, Moret J, Barreau X, Szikora I, Herbreteau D, Turjman F et al. Safety and efficacy of aneurysm treatment with WEB in the cumulative population of three prospective, multicenter series. J NEUROINTERV SURG. 2018 Jun;10(6):553-559. https://doi.org/10.1136/neurintsurg-2017-013448

Bibtex

@article{b3d5672785a14720b9acd005ad0643df,
title = "Safety and efficacy of aneurysm treatment with WEB in the cumulative population of three prospective, multicenter series",
abstract = "BACKGROUND: Flow disruption with the WEB is an innovative endovascular approach for treatment of wide-neck bifurcation aneurysms. Initial studies have shown a low complication rate with good efficacy.PURPOSE: To report clinical and anatomical results of the WEB treatment in the cumulative population of three Good Clinical Practice (GCP) studies: WEBCAST (WEB Clinical Assessment of Intrasaccular Aneurysm), French Observatory, and WEBCAST-2.METHODS: WEBCAST, French Observatory, and WEBCAST-2 are single-arm, prospective, multicenter, GCP studies dedicated to the evaluation of WEB treatment. Clinical data were independently evaluated. Postoperative and 1-year aneurysm occlusion was independently evaluated using the 3-grade scale: complete occlusion, neck remnant, and aneurysm remnant.RESULTS: The cumulative population comprised 168 patients with 169 aneurysms, including 112 female subjects (66.7%). The patients' ages ranged between 27 and 77 years (mean 55.5±10.2 years). Aneurysm locations were middle cerebral artery in 86/169 aneurysms (50.9%), anterior communicating artery in 36/169 (21.3%), basilar artery in 30/169 (17.8%), and internal carotid artery terminus in 17/169 (10.1%). The aneurysm was ruptured in 14/169 (8.3%). There was no mortality at 1 month and procedure/device-related morbidity was 1.2% (2/168). At 1 year, complete aneurysm occlusion was observed in 81/153 aneurysms (52.9%), neck remnant in 40/153 aneurysms (26.1%), and aneurysm remnant in 32/153 aneurysms (20.9%). Re-treatment was carried out in 6.9%.CONCLUSIONS: This series is at the moment the largest prospective, multicenter, GCP series of patients with aneurysms treated with WEB. It shows the high safety and good mid-term efficacy of this treatment.CLINICAL TRIAL REGISTRATION: French Observatory: Unique identifier (NCT18069); WEBCAST and WEBCAST-2: Unique identifier (NCT01778322).",
keywords = "Journal Article",
author = "Laurent Pierot and Jacques Moret and Xavier Barreau and Istvan Szikora and Denis Herbreteau and Francis Turjman and Markus Holtmannsp{\"o}tter and Anne-Christine Januel and Vincent Costalat and Jens Fiehler and Joachim Klisch and Jean-Yves Gauvrit and Werner Weber and Hubert Desal and St{\'e}phane Velasco and Thomas Liebig and Luc Stockx and Joachim Berkefeld and Andrew Molyneux and James Byrne and Laurent Spelle",
note = "{\textcopyright} Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.",
year = "2018",
month = jun,
doi = "10.1136/neurintsurg-2017-013448",
language = "English",
volume = "10",
pages = "553--559",
journal = "J NEUROINTERV SURG",
issn = "1759-8478",
publisher = "BMJ PUBLISHING GROUP",
number = "6",

}

RIS

TY - JOUR

T1 - Safety and efficacy of aneurysm treatment with WEB in the cumulative population of three prospective, multicenter series

AU - Pierot, Laurent

AU - Moret, Jacques

AU - Barreau, Xavier

AU - Szikora, Istvan

AU - Herbreteau, Denis

AU - Turjman, Francis

AU - Holtmannspötter, Markus

AU - Januel, Anne-Christine

AU - Costalat, Vincent

AU - Fiehler, Jens

AU - Klisch, Joachim

AU - Gauvrit, Jean-Yves

AU - Weber, Werner

AU - Desal, Hubert

AU - Velasco, Stéphane

AU - Liebig, Thomas

AU - Stockx, Luc

AU - Berkefeld, Joachim

AU - Molyneux, Andrew

AU - Byrne, James

AU - Spelle, Laurent

N1 - © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

PY - 2018/6

Y1 - 2018/6

N2 - BACKGROUND: Flow disruption with the WEB is an innovative endovascular approach for treatment of wide-neck bifurcation aneurysms. Initial studies have shown a low complication rate with good efficacy.PURPOSE: To report clinical and anatomical results of the WEB treatment in the cumulative population of three Good Clinical Practice (GCP) studies: WEBCAST (WEB Clinical Assessment of Intrasaccular Aneurysm), French Observatory, and WEBCAST-2.METHODS: WEBCAST, French Observatory, and WEBCAST-2 are single-arm, prospective, multicenter, GCP studies dedicated to the evaluation of WEB treatment. Clinical data were independently evaluated. Postoperative and 1-year aneurysm occlusion was independently evaluated using the 3-grade scale: complete occlusion, neck remnant, and aneurysm remnant.RESULTS: The cumulative population comprised 168 patients with 169 aneurysms, including 112 female subjects (66.7%). The patients' ages ranged between 27 and 77 years (mean 55.5±10.2 years). Aneurysm locations were middle cerebral artery in 86/169 aneurysms (50.9%), anterior communicating artery in 36/169 (21.3%), basilar artery in 30/169 (17.8%), and internal carotid artery terminus in 17/169 (10.1%). The aneurysm was ruptured in 14/169 (8.3%). There was no mortality at 1 month and procedure/device-related morbidity was 1.2% (2/168). At 1 year, complete aneurysm occlusion was observed in 81/153 aneurysms (52.9%), neck remnant in 40/153 aneurysms (26.1%), and aneurysm remnant in 32/153 aneurysms (20.9%). Re-treatment was carried out in 6.9%.CONCLUSIONS: This series is at the moment the largest prospective, multicenter, GCP series of patients with aneurysms treated with WEB. It shows the high safety and good mid-term efficacy of this treatment.CLINICAL TRIAL REGISTRATION: French Observatory: Unique identifier (NCT18069); WEBCAST and WEBCAST-2: Unique identifier (NCT01778322).

AB - BACKGROUND: Flow disruption with the WEB is an innovative endovascular approach for treatment of wide-neck bifurcation aneurysms. Initial studies have shown a low complication rate with good efficacy.PURPOSE: To report clinical and anatomical results of the WEB treatment in the cumulative population of three Good Clinical Practice (GCP) studies: WEBCAST (WEB Clinical Assessment of Intrasaccular Aneurysm), French Observatory, and WEBCAST-2.METHODS: WEBCAST, French Observatory, and WEBCAST-2 are single-arm, prospective, multicenter, GCP studies dedicated to the evaluation of WEB treatment. Clinical data were independently evaluated. Postoperative and 1-year aneurysm occlusion was independently evaluated using the 3-grade scale: complete occlusion, neck remnant, and aneurysm remnant.RESULTS: The cumulative population comprised 168 patients with 169 aneurysms, including 112 female subjects (66.7%). The patients' ages ranged between 27 and 77 years (mean 55.5±10.2 years). Aneurysm locations were middle cerebral artery in 86/169 aneurysms (50.9%), anterior communicating artery in 36/169 (21.3%), basilar artery in 30/169 (17.8%), and internal carotid artery terminus in 17/169 (10.1%). The aneurysm was ruptured in 14/169 (8.3%). There was no mortality at 1 month and procedure/device-related morbidity was 1.2% (2/168). At 1 year, complete aneurysm occlusion was observed in 81/153 aneurysms (52.9%), neck remnant in 40/153 aneurysms (26.1%), and aneurysm remnant in 32/153 aneurysms (20.9%). Re-treatment was carried out in 6.9%.CONCLUSIONS: This series is at the moment the largest prospective, multicenter, GCP series of patients with aneurysms treated with WEB. It shows the high safety and good mid-term efficacy of this treatment.CLINICAL TRIAL REGISTRATION: French Observatory: Unique identifier (NCT18069); WEBCAST and WEBCAST-2: Unique identifier (NCT01778322).

KW - Journal Article

U2 - 10.1136/neurintsurg-2017-013448

DO - 10.1136/neurintsurg-2017-013448

M3 - SCORING: Journal article

C2 - 28965106

VL - 10

SP - 553

EP - 559

JO - J NEUROINTERV SURG

JF - J NEUROINTERV SURG

SN - 1759-8478

IS - 6

ER -