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Safety and efficacy in ablation of premature ventricular contraction: data from the German ablation registry

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Safety and efficacy in ablation of premature ventricular contraction: data from the German ablation registry. / Fichtner, S; Senges, J; Hochadel, M; Tilz, R; Willems, S; Eckardt, L; Deneke, T; Lewalter, T; Dorwarth, U; Reithmann, C; Brachmann, J; Steinbeck, G; Kääb, S; German Ablation Registry.

in: CLIN RES CARDIOL, Jahrgang 106, Nr. 1, 01.2017, S. 49-57.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Fichtner, S, Senges, J, Hochadel, M, Tilz, R, Willems, S, Eckardt, L, Deneke, T, Lewalter, T, Dorwarth, U, Reithmann, C, Brachmann, J, Steinbeck, G, Kääb, S & German Ablation Registry 2017, 'Safety and efficacy in ablation of premature ventricular contraction: data from the German ablation registry', CLIN RES CARDIOL, Jg. 106, Nr. 1, S. 49-57. https://doi.org/10.1007/s00392-016-1022-9

APA

Fichtner, S., Senges, J., Hochadel, M., Tilz, R., Willems, S., Eckardt, L., Deneke, T., Lewalter, T., Dorwarth, U., Reithmann, C., Brachmann, J., Steinbeck, G., Kääb, S., & German Ablation Registry (2017). Safety and efficacy in ablation of premature ventricular contraction: data from the German ablation registry. CLIN RES CARDIOL, 106(1), 49-57. https://doi.org/10.1007/s00392-016-1022-9

Vancouver

Fichtner S, Senges J, Hochadel M, Tilz R, Willems S, Eckardt L et al. Safety and efficacy in ablation of premature ventricular contraction: data from the German ablation registry. CLIN RES CARDIOL. 2017 Jan;106(1):49-57. https://doi.org/10.1007/s00392-016-1022-9

Bibtex

@article{8dfb0249dbe6422387ea9246a9660353,
title = "Safety and efficacy in ablation of premature ventricular contraction: data from the German ablation registry",
abstract = "BACKGROUND: Patients with frequent premature ventricular contractions (PVCs) are often highly symptomatic with significantly reduced quality-of-life. We evaluated the outcome and success of PVC ablation in patients in the German Ablation Registry.METHODS: The German Ablation Registry is a nationwide prospective multicenter database of patients who underwent an ablation procedure, initiated by the {"}Stiftung Institut f{\"u}r Herzinfarktforschung{"} (IHF), Ludwigshafen, Germany. Data were acquired from March 2007 to May 2011. Patients underwent PVC ablation in the enrolling ablation centers.RESULTS: A total of 408 patients (age 53.5 ± 15 years, 55 % female) undergoing ablation for PVCs were included. 32 % of patients showed a co-existing structural heart disease. Acute ablation success of the procedure was 82 % in the overall patient group. In patients without structural heart disease, acute success was significantly higher compared with patients with structural heart disease (86 vs. 74 %, p = 0.002). All patients were discharged alive after a median of 3 days. No patient suffered an acute myocardial infarction, stroke, or major bleeding. After 12 months' follow-up, 99 % of patients were still alive showing a significant different mortality between patients with structural heart disease compared with those without (2.3 vs. 0 %, p = 0.012). In addition, 76 % of patients showed significantly improved symptoms after 12 months of follow-up.CONCLUSION: Based on the data from this registry, ablation of PVCs is a safe and efficient procedure with an excellent outcome and improved symptoms after 12 months.",
keywords = "Adult, Aged, Catheter Ablation/adverse effects, Electrocardiography, Female, Germany, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Postoperative Complications/etiology, Registries, Risk Factors, Time Factors, Treatment Outcome, Ventricular Premature Complexes/diagnosis",
author = "S Fichtner and J Senges and M Hochadel and R Tilz and S Willems and L Eckardt and T Deneke and T Lewalter and U Dorwarth and C Reithmann and J Brachmann and G Steinbeck and S K{\"a}{\"a}b and {German Ablation Registry}",
year = "2017",
month = jan,
doi = "10.1007/s00392-016-1022-9",
language = "English",
volume = "106",
pages = "49--57",
journal = "CLIN RES CARDIOL",
issn = "1861-0684",
publisher = "D. Steinkopff-Verlag",
number = "1",

}

RIS

TY - JOUR

T1 - Safety and efficacy in ablation of premature ventricular contraction: data from the German ablation registry

AU - Fichtner, S

AU - Senges, J

AU - Hochadel, M

AU - Tilz, R

AU - Willems, S

AU - Eckardt, L

AU - Deneke, T

AU - Lewalter, T

AU - Dorwarth, U

AU - Reithmann, C

AU - Brachmann, J

AU - Steinbeck, G

AU - Kääb, S

AU - German Ablation Registry

PY - 2017/1

Y1 - 2017/1

N2 - BACKGROUND: Patients with frequent premature ventricular contractions (PVCs) are often highly symptomatic with significantly reduced quality-of-life. We evaluated the outcome and success of PVC ablation in patients in the German Ablation Registry.METHODS: The German Ablation Registry is a nationwide prospective multicenter database of patients who underwent an ablation procedure, initiated by the "Stiftung Institut für Herzinfarktforschung" (IHF), Ludwigshafen, Germany. Data were acquired from March 2007 to May 2011. Patients underwent PVC ablation in the enrolling ablation centers.RESULTS: A total of 408 patients (age 53.5 ± 15 years, 55 % female) undergoing ablation for PVCs were included. 32 % of patients showed a co-existing structural heart disease. Acute ablation success of the procedure was 82 % in the overall patient group. In patients without structural heart disease, acute success was significantly higher compared with patients with structural heart disease (86 vs. 74 %, p = 0.002). All patients were discharged alive after a median of 3 days. No patient suffered an acute myocardial infarction, stroke, or major bleeding. After 12 months' follow-up, 99 % of patients were still alive showing a significant different mortality between patients with structural heart disease compared with those without (2.3 vs. 0 %, p = 0.012). In addition, 76 % of patients showed significantly improved symptoms after 12 months of follow-up.CONCLUSION: Based on the data from this registry, ablation of PVCs is a safe and efficient procedure with an excellent outcome and improved symptoms after 12 months.

AB - BACKGROUND: Patients with frequent premature ventricular contractions (PVCs) are often highly symptomatic with significantly reduced quality-of-life. We evaluated the outcome and success of PVC ablation in patients in the German Ablation Registry.METHODS: The German Ablation Registry is a nationwide prospective multicenter database of patients who underwent an ablation procedure, initiated by the "Stiftung Institut für Herzinfarktforschung" (IHF), Ludwigshafen, Germany. Data were acquired from March 2007 to May 2011. Patients underwent PVC ablation in the enrolling ablation centers.RESULTS: A total of 408 patients (age 53.5 ± 15 years, 55 % female) undergoing ablation for PVCs were included. 32 % of patients showed a co-existing structural heart disease. Acute ablation success of the procedure was 82 % in the overall patient group. In patients without structural heart disease, acute success was significantly higher compared with patients with structural heart disease (86 vs. 74 %, p = 0.002). All patients were discharged alive after a median of 3 days. No patient suffered an acute myocardial infarction, stroke, or major bleeding. After 12 months' follow-up, 99 % of patients were still alive showing a significant different mortality between patients with structural heart disease compared with those without (2.3 vs. 0 %, p = 0.012). In addition, 76 % of patients showed significantly improved symptoms after 12 months of follow-up.CONCLUSION: Based on the data from this registry, ablation of PVCs is a safe and efficient procedure with an excellent outcome and improved symptoms after 12 months.

KW - Adult

KW - Aged

KW - Catheter Ablation/adverse effects

KW - Electrocardiography

KW - Female

KW - Germany

KW - Humans

KW - Kaplan-Meier Estimate

KW - Male

KW - Middle Aged

KW - Postoperative Complications/etiology

KW - Registries

KW - Risk Factors

KW - Time Factors

KW - Treatment Outcome

KW - Ventricular Premature Complexes/diagnosis

U2 - 10.1007/s00392-016-1022-9

DO - 10.1007/s00392-016-1022-9

M3 - SCORING: Journal article

C2 - 27484499

VL - 106

SP - 49

EP - 57

JO - CLIN RES CARDIOL

JF - CLIN RES CARDIOL

SN - 1861-0684

IS - 1

ER -