Role of chemokines in glomerular diseases.
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Role of chemokines in glomerular diseases. / Banas, B; Wenzel, Ulrich; Stahl, R A; Schlöndorff, D.
in: KIDNEY BLOOD PRESS R, Jahrgang 19, Nr. 5, 5, 1996, S. 270-280.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Role of chemokines in glomerular diseases.
AU - Banas, B
AU - Wenzel, Ulrich
AU - Stahl, R A
AU - Schlöndorff, D
PY - 1996
Y1 - 1996
N2 - Various immunological and nonimmunological glomerular diseases were found to be associated with an influx of leukocytes into the diseased kidney. Chemotactic factors are likely to play an important role in determining the characteristic cellular infiltration. The human superfamily of chemoattractant cytokines -so-called chemokines-comprises over 20 members which show different properties in targeting specific subpopulations of leukocytes. Expression and effects of chemokines in renal cell culture, animal models of kidney diseases, and human glomerular diseases are reviewed. A better knowledge of chemokine action and regulation during glomerular inflammation may help to explore new therapeutic strategies in the future.
AB - Various immunological and nonimmunological glomerular diseases were found to be associated with an influx of leukocytes into the diseased kidney. Chemotactic factors are likely to play an important role in determining the characteristic cellular infiltration. The human superfamily of chemoattractant cytokines -so-called chemokines-comprises over 20 members which show different properties in targeting specific subpopulations of leukocytes. Expression and effects of chemokines in renal cell culture, animal models of kidney diseases, and human glomerular diseases are reviewed. A better knowledge of chemokine action and regulation during glomerular inflammation may help to explore new therapeutic strategies in the future.
M3 - SCORING: Zeitschriftenaufsatz
VL - 19
SP - 270
EP - 280
JO - KIDNEY BLOOD PRESS R
JF - KIDNEY BLOOD PRESS R
SN - 1420-4096
IS - 5
M1 - 5
ER -