Role and mechanism of BMP4 in bone, craniofacial, and tooth development

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Role and mechanism of BMP4 in bone, craniofacial, and tooth development. / Ye, Yuer; Jiang, Zhiwei; Pan, Yiqi; Yang, Guoli; Wang, Ying.

in: ARCH ORAL BIOL, Jahrgang 140, 105465, 08.2022.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ReviewForschung

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@article{d716976fac894a4ba58ca08f5895afbf,
title = "Role and mechanism of BMP4 in bone, craniofacial, and tooth development",
abstract = "OBJECTIVE: This review aimed to present an overview of the effect of bone morphogenetic protein 4 (BMP4) on craniofacial and skeletal development, particularly the specific role of BMP4 in tooth development.DESIGN: The search for this narrative review was conducted in PubMed, Web of Science, Embase, and ScienceDirect using relevant keywords, including checking reference lists of journal articles by hand searching.RESULTS: Mutations or deletions of BMP4 cause tissue development defects in mice and humans, such as fragile bone, craniofacial deformity, cleft lip and palate, tooth development stagnation, and abnormal structure.CONCLUSIONS: BMP4 is a reliable and vital candidate to regulate the development of bones, craniofacies, and teeth. It also has high clinical application potential.",
keywords = "Animals, Bone Morphogenetic Protein 4/genetics, Cleft Lip/genetics, Cleft Palate/genetics, Mice, Odontogenesis/genetics, Tooth",
author = "Yuer Ye and Zhiwei Jiang and Yiqi Pan and Guoli Yang and Ying Wang",
note = "Copyright {\textcopyright} 2022 Elsevier Ltd. All rights reserved.",
year = "2022",
month = aug,
doi = "10.1016/j.archoralbio.2022.105465",
language = "English",
volume = "140",
journal = "ARCH ORAL BIOL",
issn = "0003-9969",
publisher = "Elsevier Limited",

}

RIS

TY - JOUR

T1 - Role and mechanism of BMP4 in bone, craniofacial, and tooth development

AU - Ye, Yuer

AU - Jiang, Zhiwei

AU - Pan, Yiqi

AU - Yang, Guoli

AU - Wang, Ying

N1 - Copyright © 2022 Elsevier Ltd. All rights reserved.

PY - 2022/8

Y1 - 2022/8

N2 - OBJECTIVE: This review aimed to present an overview of the effect of bone morphogenetic protein 4 (BMP4) on craniofacial and skeletal development, particularly the specific role of BMP4 in tooth development.DESIGN: The search for this narrative review was conducted in PubMed, Web of Science, Embase, and ScienceDirect using relevant keywords, including checking reference lists of journal articles by hand searching.RESULTS: Mutations or deletions of BMP4 cause tissue development defects in mice and humans, such as fragile bone, craniofacial deformity, cleft lip and palate, tooth development stagnation, and abnormal structure.CONCLUSIONS: BMP4 is a reliable and vital candidate to regulate the development of bones, craniofacies, and teeth. It also has high clinical application potential.

AB - OBJECTIVE: This review aimed to present an overview of the effect of bone morphogenetic protein 4 (BMP4) on craniofacial and skeletal development, particularly the specific role of BMP4 in tooth development.DESIGN: The search for this narrative review was conducted in PubMed, Web of Science, Embase, and ScienceDirect using relevant keywords, including checking reference lists of journal articles by hand searching.RESULTS: Mutations or deletions of BMP4 cause tissue development defects in mice and humans, such as fragile bone, craniofacial deformity, cleft lip and palate, tooth development stagnation, and abnormal structure.CONCLUSIONS: BMP4 is a reliable and vital candidate to regulate the development of bones, craniofacies, and teeth. It also has high clinical application potential.

KW - Animals

KW - Bone Morphogenetic Protein 4/genetics

KW - Cleft Lip/genetics

KW - Cleft Palate/genetics

KW - Mice

KW - Odontogenesis/genetics

KW - Tooth

U2 - 10.1016/j.archoralbio.2022.105465

DO - 10.1016/j.archoralbio.2022.105465

M3 - SCORING: Review article

C2 - 35662681

VL - 140

JO - ARCH ORAL BIOL

JF - ARCH ORAL BIOL

SN - 0003-9969

M1 - 105465

ER -