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Risk profiles for heavy drinking in adolescence: differential effects of gender

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Risk profiles for heavy drinking in adolescence: differential effects of gender. / Seo, Sambu; Beck, Anne; Matthis, Caroline; Genauck, Alexander; Banaschewski, Tobias; Bokde, Arun L W; Bromberg, Uli; Büchel, Christian; Quinlan, Erin Burke; Flor, Herta; Frouin, Vincent; Garavan, Hugh; Gowland, Penny; Ittermann, Bernd; Martinot, Jean-Luc; Paillère Martinot, Marie-Laure; Nees, Frauke; Papadopoulos Orfanos, Dimitri; Poustka, Luise; Hohmann, Sarah; Fröhner, Juliane H; Smolka, Michael N; Walter, Henrik; Whelan, Robert; Desrivières, Sylvane; Heinz, Andreas; Schumann, Gunter; Obermayer, Klaus.

in: ADDICT BIOL, Jahrgang 24, Nr. 4, 07.2019, S. 787-801.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Seo, S, Beck, A, Matthis, C, Genauck, A, Banaschewski, T, Bokde, ALW, Bromberg, U, Büchel, C, Quinlan, EB, Flor, H, Frouin, V, Garavan, H, Gowland, P, Ittermann, B, Martinot, J-L, Paillère Martinot, M-L, Nees, F, Papadopoulos Orfanos, D, Poustka, L, Hohmann, S, Fröhner, JH, Smolka, MN, Walter, H, Whelan, R, Desrivières, S, Heinz, A, Schumann, G & Obermayer, K 2019, 'Risk profiles for heavy drinking in adolescence: differential effects of gender', ADDICT BIOL, Jg. 24, Nr. 4, S. 787-801. https://doi.org/10.1111/adb.12636

APA

Seo, S., Beck, A., Matthis, C., Genauck, A., Banaschewski, T., Bokde, A. L. W., Bromberg, U., Büchel, C., Quinlan, E. B., Flor, H., Frouin, V., Garavan, H., Gowland, P., Ittermann, B., Martinot, J-L., Paillère Martinot, M-L., Nees, F., Papadopoulos Orfanos, D., Poustka, L., ... Obermayer, K. (2019). Risk profiles for heavy drinking in adolescence: differential effects of gender. ADDICT BIOL, 24(4), 787-801. https://doi.org/10.1111/adb.12636

Vancouver

Seo S, Beck A, Matthis C, Genauck A, Banaschewski T, Bokde ALW et al. Risk profiles for heavy drinking in adolescence: differential effects of gender. ADDICT BIOL. 2019 Jul;24(4):787-801. https://doi.org/10.1111/adb.12636

Bibtex

@article{57627341a54b4b9d93a2a1c5d09bce3c,
title = "Risk profiles for heavy drinking in adolescence: differential effects of gender",
abstract = "Abnormalities across different domains of neuropsychological functioning may constitute a risk factor for heavy drinking during adolescence and for developing alcohol use disorders later in life. However, the exact nature of such multi-domain risk profiles is unclear, and it is further unclear whether these risk profiles differ between genders. We combined longitudinal and cross-sectional analyses on the large IMAGEN sample (N ≈ 1000) to predict heavy drinking at age 19 from gray matter volume as well as from psychosocial data at age 14 and 19-for males and females separately. Heavy drinking was associated with reduced gray matter volume in 19-year-olds' bilateral ACC, MPFC, thalamus, middle, medial and superior OFC as well as left amygdala and anterior insula and right inferior OFC. Notably, this lower gray matter volume associated with heavy drinking was stronger in females than in males. In both genders, we observed that impulsivity and facets of novelty seeking at the age of 14 and 19, as well as hopelessness at the age of 14, are risk factors for heavy drinking at the age of 19. Stressful life events with internal (but not external) locus of control were associated with heavy drinking only at age 19. Personality and stress assessment in adolescents may help to better target counseling and prevention programs. This might reduce heavy drinking in adolescents and hence reduce the risk of early brain atrophy, especially in females. In turn, this could additionally reduce the risk of developing alcohol use disorders later in adulthood.",
author = "Sambu Seo and Anne Beck and Caroline Matthis and Alexander Genauck and Tobias Banaschewski and Bokde, {Arun L W} and Uli Bromberg and Christian B{\"u}chel and Quinlan, {Erin Burke} and Herta Flor and Vincent Frouin and Hugh Garavan and Penny Gowland and Bernd Ittermann and Jean-Luc Martinot and {Paill{\`e}re Martinot}, Marie-Laure and Frauke Nees and {Papadopoulos Orfanos}, Dimitri and Luise Poustka and Sarah Hohmann and Fr{\"o}hner, {Juliane H} and Smolka, {Michael N} and Henrik Walter and Robert Whelan and Sylvane Desrivi{\`e}res and Andreas Heinz and Gunter Schumann and Klaus Obermayer",
note = "{\textcopyright} 2018 Society for the Study of Addiction.",
year = "2019",
month = jul,
doi = "10.1111/adb.12636",
language = "English",
volume = "24",
pages = "787--801",
journal = "ADDICT BIOL",
issn = "1355-6215",
publisher = "Wiley-Blackwell",
number = "4",

}

RIS

TY - JOUR

T1 - Risk profiles for heavy drinking in adolescence: differential effects of gender

AU - Seo, Sambu

AU - Beck, Anne

AU - Matthis, Caroline

AU - Genauck, Alexander

AU - Banaschewski, Tobias

AU - Bokde, Arun L W

AU - Bromberg, Uli

AU - Büchel, Christian

AU - Quinlan, Erin Burke

AU - Flor, Herta

AU - Frouin, Vincent

AU - Garavan, Hugh

AU - Gowland, Penny

AU - Ittermann, Bernd

AU - Martinot, Jean-Luc

AU - Paillère Martinot, Marie-Laure

AU - Nees, Frauke

AU - Papadopoulos Orfanos, Dimitri

AU - Poustka, Luise

AU - Hohmann, Sarah

AU - Fröhner, Juliane H

AU - Smolka, Michael N

AU - Walter, Henrik

AU - Whelan, Robert

AU - Desrivières, Sylvane

AU - Heinz, Andreas

AU - Schumann, Gunter

AU - Obermayer, Klaus

N1 - © 2018 Society for the Study of Addiction.

PY - 2019/7

Y1 - 2019/7

N2 - Abnormalities across different domains of neuropsychological functioning may constitute a risk factor for heavy drinking during adolescence and for developing alcohol use disorders later in life. However, the exact nature of such multi-domain risk profiles is unclear, and it is further unclear whether these risk profiles differ between genders. We combined longitudinal and cross-sectional analyses on the large IMAGEN sample (N ≈ 1000) to predict heavy drinking at age 19 from gray matter volume as well as from psychosocial data at age 14 and 19-for males and females separately. Heavy drinking was associated with reduced gray matter volume in 19-year-olds' bilateral ACC, MPFC, thalamus, middle, medial and superior OFC as well as left amygdala and anterior insula and right inferior OFC. Notably, this lower gray matter volume associated with heavy drinking was stronger in females than in males. In both genders, we observed that impulsivity and facets of novelty seeking at the age of 14 and 19, as well as hopelessness at the age of 14, are risk factors for heavy drinking at the age of 19. Stressful life events with internal (but not external) locus of control were associated with heavy drinking only at age 19. Personality and stress assessment in adolescents may help to better target counseling and prevention programs. This might reduce heavy drinking in adolescents and hence reduce the risk of early brain atrophy, especially in females. In turn, this could additionally reduce the risk of developing alcohol use disorders later in adulthood.

AB - Abnormalities across different domains of neuropsychological functioning may constitute a risk factor for heavy drinking during adolescence and for developing alcohol use disorders later in life. However, the exact nature of such multi-domain risk profiles is unclear, and it is further unclear whether these risk profiles differ between genders. We combined longitudinal and cross-sectional analyses on the large IMAGEN sample (N ≈ 1000) to predict heavy drinking at age 19 from gray matter volume as well as from psychosocial data at age 14 and 19-for males and females separately. Heavy drinking was associated with reduced gray matter volume in 19-year-olds' bilateral ACC, MPFC, thalamus, middle, medial and superior OFC as well as left amygdala and anterior insula and right inferior OFC. Notably, this lower gray matter volume associated with heavy drinking was stronger in females than in males. In both genders, we observed that impulsivity and facets of novelty seeking at the age of 14 and 19, as well as hopelessness at the age of 14, are risk factors for heavy drinking at the age of 19. Stressful life events with internal (but not external) locus of control were associated with heavy drinking only at age 19. Personality and stress assessment in adolescents may help to better target counseling and prevention programs. This might reduce heavy drinking in adolescents and hence reduce the risk of early brain atrophy, especially in females. In turn, this could additionally reduce the risk of developing alcohol use disorders later in adulthood.

U2 - 10.1111/adb.12636

DO - 10.1111/adb.12636

M3 - SCORING: Journal article

C2 - 29847018

VL - 24

SP - 787

EP - 801

JO - ADDICT BIOL

JF - ADDICT BIOL

SN - 1355-6215

IS - 4

ER -