Risk assessment of metastatic recurrence in patients with prostate cancer by using the Cancer of the Prostate Risk Assessment score: results from 2937 European patients.

  • Lars Budäus
  • Hendrik Isbarn
  • Pierre Tennstedt
  • Georg Salomon
  • Thorsten Schlomm
  • Thomas Steuber
  • Alexander Haese
  • Felix Chun
  • Margit Fisch
  • Uwe Michl
  • Hans Heinzer
  • Hartwig Huland
  • Markus Graefen

Beteiligte Einrichtungen

Abstract

Study Type--Prognosis (case series) Level of Evidence 4. What's known on the subject? and What does the study add? Different tools allow the individual estimation of the various endpoints in patients with prostate cancer. The Cancer of the Prostate Risk Assessment (CAPRA) score is an easy to calculate prediction tool, based on a large population based database. However, little is known about the performance of this prediction tool in European patients. The data obtained in the present study demonstrate differences in tumour characteristics between European patients and the initial development cohort from the USA. However, the concordance index of the CAPRA scores for predicting biochemical recurrence and metastatic recurrence was 76.2 and 78.5, respectively, in European patients. Therefore, the CAPRA score also allows reliable prediction of the examined endpoints in European patients.

Bibliografische Daten

OriginalspracheEnglisch
Aufsatznummer11
ISSN1464-4096
DOIs
StatusVeröffentlicht - 12.2012