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Risk and outcomes of complications during and after MitraClip implantation: Experience in 828 patients from the German TRAnscatheter mitral valve interventions (TRAMI) registry

Standard

Risk and outcomes of complications during and after MitraClip implantation: Experience in 828 patients from the German TRAnscatheter mitral valve interventions (TRAMI) registry. / Eggebrecht, Holger; Schelle, Sibylle; Puls, Miriam; Plicht, Björn; von Bardeleben, Ralph Stephan; Butter, Christian; May, Andreas E; Lubos, Edith; Boekstegers, Peter; Ouarrak, Taoufik; Senges, Jochen; Schmermund, Axel.

in: CATHETER CARDIO INTE, Jahrgang 86, Nr. 4, 10.2015, S. 728-735.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Eggebrecht, H, Schelle, S, Puls, M, Plicht, B, von Bardeleben, RS, Butter, C, May, AE, Lubos, E, Boekstegers, P, Ouarrak, T, Senges, J & Schmermund, A 2015, 'Risk and outcomes of complications during and after MitraClip implantation: Experience in 828 patients from the German TRAnscatheter mitral valve interventions (TRAMI) registry', CATHETER CARDIO INTE, Jg. 86, Nr. 4, S. 728-735. https://doi.org/10.1002/ccd.25838

APA

Eggebrecht, H., Schelle, S., Puls, M., Plicht, B., von Bardeleben, R. S., Butter, C., May, A. E., Lubos, E., Boekstegers, P., Ouarrak, T., Senges, J., & Schmermund, A. (2015). Risk and outcomes of complications during and after MitraClip implantation: Experience in 828 patients from the German TRAnscatheter mitral valve interventions (TRAMI) registry. CATHETER CARDIO INTE, 86(4), 728-735. https://doi.org/10.1002/ccd.25838

Vancouver

Eggebrecht H, Schelle S, Puls M, Plicht B, von Bardeleben RS, Butter C et al. Risk and outcomes of complications during and after MitraClip implantation: Experience in 828 patients from the German TRAnscatheter mitral valve interventions (TRAMI) registry. CATHETER CARDIO INTE. 2015 Okt;86(4):728-735. https://doi.org/10.1002/ccd.25838

Bibtex

@article{ed71e9f956ce4fc79aa3c4e5f11a54a2,
title = "Risk and outcomes of complications during and after MitraClip implantation: Experience in 828 patients from the German TRAnscatheter mitral valve interventions (TRAMI) registry",
abstract = "AIMS: To analyze risk and outcomes of complications during and after MitraClip implantation using multicenter data from the prospective German Transcatheter Mitral Valve Interventions (TRAMI) registry.METHODS AND RESULTS: Data of 828 patients (mean age: 76.0 [71-81] years, 327 (40%) females) undergoing MitraClip implantation in Germany between 2010 and 2013 were analyzed. Most patients (85%) underwent elective procedures with on average implantation of 1.4 ± 0.6 clips. Emergent cardiac surgery was not required; a single patient died intraoperatively. During the in-hospital period, complications occurred in 215 (25.9%) patients, of which 106 (12.8%) were considered major. Major bleeding complications were among the most frequent major complications (7.4%), while rates of pericardial tamponade (1.9%) and clip-specific complications (embolization: 0%, partial clip detachment: 1.9%) were low. In-hospital death, stroke or myocardial infarction (MACCE) occurred in 2.2, 0.9, and 0% patients, respectively. Patients with complications appeared to be older and more critically ill pre-interventionally; in-hospital mortality was significantly higher as compared to those without procedural complications.CONCLUSIONS: MitraClip implantation appears to be a safe treatment option with low rates of MACCE and clip-specific complications. Nevertheless, MitraClip therapy is not without complications. Careful patient selection and improvements in preventing peri-procedural bleeding have the potential of reducing post-procedural complications and improving outcomes.",
keywords = "Aged, Aged, 80 and over, Cardiac Catheterization/adverse effects, Chi-Square Distribution, Cohort Studies, Elective Surgical Procedures/adverse effects, Female, Follow-Up Studies, Germany, Heart Valve Prosthesis, Heart Valve Prosthesis Implantation/adverse effects, Hospital Mortality/trends, Humans, Male, Mitral Valve Insufficiency/diagnostic imaging, Patient Safety, Prosthesis Design, Prosthesis Failure, Registries, Retrospective Studies, Risk Assessment, Statistics, Nonparametric, Survival Rate, Treatment Outcome, Ultrasonography",
author = "Holger Eggebrecht and Sibylle Schelle and Miriam Puls and Bj{\"o}rn Plicht and {von Bardeleben}, {Ralph Stephan} and Christian Butter and May, {Andreas E} and Edith Lubos and Peter Boekstegers and Taoufik Ouarrak and Jochen Senges and Axel Schmermund",
note = "{\textcopyright} 2015 Wiley Periodicals, Inc.",
year = "2015",
month = oct,
doi = "10.1002/ccd.25838",
language = "English",
volume = "86",
pages = "728--735",
journal = "CATHETER CARDIO INTE",
issn = "1522-1946",
publisher = "Wiley-Liss Inc.",
number = "4",

}

RIS

TY - JOUR

T1 - Risk and outcomes of complications during and after MitraClip implantation: Experience in 828 patients from the German TRAnscatheter mitral valve interventions (TRAMI) registry

AU - Eggebrecht, Holger

AU - Schelle, Sibylle

AU - Puls, Miriam

AU - Plicht, Björn

AU - von Bardeleben, Ralph Stephan

AU - Butter, Christian

AU - May, Andreas E

AU - Lubos, Edith

AU - Boekstegers, Peter

AU - Ouarrak, Taoufik

AU - Senges, Jochen

AU - Schmermund, Axel

N1 - © 2015 Wiley Periodicals, Inc.

PY - 2015/10

Y1 - 2015/10

N2 - AIMS: To analyze risk and outcomes of complications during and after MitraClip implantation using multicenter data from the prospective German Transcatheter Mitral Valve Interventions (TRAMI) registry.METHODS AND RESULTS: Data of 828 patients (mean age: 76.0 [71-81] years, 327 (40%) females) undergoing MitraClip implantation in Germany between 2010 and 2013 were analyzed. Most patients (85%) underwent elective procedures with on average implantation of 1.4 ± 0.6 clips. Emergent cardiac surgery was not required; a single patient died intraoperatively. During the in-hospital period, complications occurred in 215 (25.9%) patients, of which 106 (12.8%) were considered major. Major bleeding complications were among the most frequent major complications (7.4%), while rates of pericardial tamponade (1.9%) and clip-specific complications (embolization: 0%, partial clip detachment: 1.9%) were low. In-hospital death, stroke or myocardial infarction (MACCE) occurred in 2.2, 0.9, and 0% patients, respectively. Patients with complications appeared to be older and more critically ill pre-interventionally; in-hospital mortality was significantly higher as compared to those without procedural complications.CONCLUSIONS: MitraClip implantation appears to be a safe treatment option with low rates of MACCE and clip-specific complications. Nevertheless, MitraClip therapy is not without complications. Careful patient selection and improvements in preventing peri-procedural bleeding have the potential of reducing post-procedural complications and improving outcomes.

AB - AIMS: To analyze risk and outcomes of complications during and after MitraClip implantation using multicenter data from the prospective German Transcatheter Mitral Valve Interventions (TRAMI) registry.METHODS AND RESULTS: Data of 828 patients (mean age: 76.0 [71-81] years, 327 (40%) females) undergoing MitraClip implantation in Germany between 2010 and 2013 were analyzed. Most patients (85%) underwent elective procedures with on average implantation of 1.4 ± 0.6 clips. Emergent cardiac surgery was not required; a single patient died intraoperatively. During the in-hospital period, complications occurred in 215 (25.9%) patients, of which 106 (12.8%) were considered major. Major bleeding complications were among the most frequent major complications (7.4%), while rates of pericardial tamponade (1.9%) and clip-specific complications (embolization: 0%, partial clip detachment: 1.9%) were low. In-hospital death, stroke or myocardial infarction (MACCE) occurred in 2.2, 0.9, and 0% patients, respectively. Patients with complications appeared to be older and more critically ill pre-interventionally; in-hospital mortality was significantly higher as compared to those without procedural complications.CONCLUSIONS: MitraClip implantation appears to be a safe treatment option with low rates of MACCE and clip-specific complications. Nevertheless, MitraClip therapy is not without complications. Careful patient selection and improvements in preventing peri-procedural bleeding have the potential of reducing post-procedural complications and improving outcomes.

KW - Aged

KW - Aged, 80 and over

KW - Cardiac Catheterization/adverse effects

KW - Chi-Square Distribution

KW - Cohort Studies

KW - Elective Surgical Procedures/adverse effects

KW - Female

KW - Follow-Up Studies

KW - Germany

KW - Heart Valve Prosthesis

KW - Heart Valve Prosthesis Implantation/adverse effects

KW - Hospital Mortality/trends

KW - Humans

KW - Male

KW - Mitral Valve Insufficiency/diagnostic imaging

KW - Patient Safety

KW - Prosthesis Design

KW - Prosthesis Failure

KW - Registries

KW - Retrospective Studies

KW - Risk Assessment

KW - Statistics, Nonparametric

KW - Survival Rate

KW - Treatment Outcome

KW - Ultrasonography

U2 - 10.1002/ccd.25838

DO - 10.1002/ccd.25838

M3 - SCORING: Journal article

C2 - 25601532

VL - 86

SP - 728

EP - 735

JO - CATHETER CARDIO INTE

JF - CATHETER CARDIO INTE

SN - 1522-1946

IS - 4

ER -