Renal function in congenital anomalies of the kidney and urinary tract.
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Renal function in congenital anomalies of the kidney and urinary tract. / Kemper, Markus J.; Müller-Wiefel, D E.
in: CURR OPIN UROL, Jahrgang 11, Nr. 6, 6, 2001, S. 571-575.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Renal function in congenital anomalies of the kidney and urinary tract.
AU - Kemper, Markus J.
AU - Müller-Wiefel, D E
PY - 2001
Y1 - 2001
N2 - Congenital anomalies of the kidneys and urinary tract are a major cause of chronic and end-stage renal failure in children. The molecular mechanisms having been elaborated, there is now growing evidence that kidney function is to a large extent determined genetically at an early stage. Assessment of kidney function is an important tool in clinical medicine and is feasible in utero. Postnatally, determination of absolute glomerular filtration rate and also of split and excretory renal function play an important role in the determination of treatment and prognosis. This is supplemented by other biochemical, molecular and interventional prognostic factors, which are of help in preservation of kidney survival by minimizing modulating factors. If chronic or terminal renal failure ensues in childhood or even in early infancy, however, improved medical care has led to encouraging results, ultimately influencing the motivation in the care of children with congenital anomalies of the kidney and urinary tract.
AB - Congenital anomalies of the kidneys and urinary tract are a major cause of chronic and end-stage renal failure in children. The molecular mechanisms having been elaborated, there is now growing evidence that kidney function is to a large extent determined genetically at an early stage. Assessment of kidney function is an important tool in clinical medicine and is feasible in utero. Postnatally, determination of absolute glomerular filtration rate and also of split and excretory renal function play an important role in the determination of treatment and prognosis. This is supplemented by other biochemical, molecular and interventional prognostic factors, which are of help in preservation of kidney survival by minimizing modulating factors. If chronic or terminal renal failure ensues in childhood or even in early infancy, however, improved medical care has led to encouraging results, ultimately influencing the motivation in the care of children with congenital anomalies of the kidney and urinary tract.
KW - Humans
KW - Female
KW - Risk Factors
KW - Child
KW - Infant
KW - Infant, Newborn
KW - Pregnancy
KW - Kidney/abnormalities/physiopathology
KW - Kidney Failure, Chronic/etiology/prevention & control
KW - Prenatal Diagnosis
KW - Renal Insufficiency/etiology/prevention & control
KW - Urinary Tract/abnormalities
KW - Humans
KW - Female
KW - Risk Factors
KW - Child
KW - Infant
KW - Infant, Newborn
KW - Pregnancy
KW - Kidney/abnormalities/physiopathology
KW - Kidney Failure, Chronic/etiology/prevention & control
KW - Prenatal Diagnosis
KW - Renal Insufficiency/etiology/prevention & control
KW - Urinary Tract/abnormalities
M3 - SCORING: Journal article
VL - 11
SP - 571
EP - 575
JO - CURR OPIN UROL
JF - CURR OPIN UROL
SN - 0963-0643
IS - 6
M1 - 6
ER -
