Regulation of Eicosanoid Pathways by MicroRNAs
Standard
Regulation of Eicosanoid Pathways by MicroRNAs. / Saul, Meike J; Emmerich, Anne C; Steinhilber, Dieter; Suess, Beatrix.
in: FRONT PHARMACOL, Jahrgang 10, 2019, S. 824.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Regulation of Eicosanoid Pathways by MicroRNAs
AU - Saul, Meike J
AU - Emmerich, Anne C
AU - Steinhilber, Dieter
AU - Suess, Beatrix
PY - 2019
Y1 - 2019
N2 - Over the last years, many microRNAs (miRNAs) have been identified that regulate the formation of bioactive lipid mediators such as prostanoids and leukotrienes. Many of these miRNAs are involved in complex regulatory circuits necessary for the fine-tuning of biological functions including inflammatory processes or cell growth. A better understanding of these networks will contribute to the development of novel therapeutic strategies for the treatment of inflammatory diseases and cancer. In this review, we provide an overview of the current knowledge of miRNA regulation in eicosanoid pathways with special focus on novel miRNA functions and regulatory circuits of leukotriene and prostaglandin biosynthesis.
AB - Over the last years, many microRNAs (miRNAs) have been identified that regulate the formation of bioactive lipid mediators such as prostanoids and leukotrienes. Many of these miRNAs are involved in complex regulatory circuits necessary for the fine-tuning of biological functions including inflammatory processes or cell growth. A better understanding of these networks will contribute to the development of novel therapeutic strategies for the treatment of inflammatory diseases and cancer. In this review, we provide an overview of the current knowledge of miRNA regulation in eicosanoid pathways with special focus on novel miRNA functions and regulatory circuits of leukotriene and prostaglandin biosynthesis.
U2 - 10.3389/fphar.2019.00824
DO - 10.3389/fphar.2019.00824
M3 - SCORING: Review article
C2 - 31379585
VL - 10
SP - 824
JO - FRONT PHARMACOL
JF - FRONT PHARMACOL
SN - 1663-9812
ER -