Reference values for exercise blood pressure in adolescents

TY - JOUR

T1 - Reference values for exercise blood pressure in adolescents

AU - Hacke, Claudia

AU - Weisser, Burkhard

PY - 2014

Y1 - 2014

N2 - In children and adolescents, office blood pressure (BP) is not very reliableand has a poor reproducibility. In case of adults, exercise BP correlatesmore closely with cardiovascular risk and there are cut-off values for ex-ercise BP which indicate normal and reference values. However, there re no reference values for children and adolescents, to date. The goal ofthe present investigation was a proposal for exercise BP reference valuesfor adolescents. In the Kiel EX.PRESS. (EXercise and PRESSure) study,systolic BP at rest and during exercise of 532 young subjects (aged 12-17 years) were determined. Systolic exercise BP was measured at 1.5Watt / kg body weight using a standardized cycle ergometer exercise test.Mean resting BP was 113.1±12.8 / 57.2±7.1 mmHg, while mean exercise BP was 149.9±19.8 / 54.2±8.6 mmHg. For the determination ofreference values, the German age-, height- and sex-related reference per-centiles for resting BP were used. The BP values at the 90th and the95th percentile were taken to determine the respective percentiles in ourstudy group. The corresponding percentiles were 87.6 and 92.1, thereforeaccording to German reference values which are very similar to interna-tional data 12.4% of the subjects had at least a high normal resting BPand 7.9% had hypertension. The systolic exercise BP values at these per-centiles for our sample are proposed as reference values for high normalexercise BP and exercise hypertension (see table 1). Using these referencevalues, 79% of our participants had normal resting and exercise BP values.7.8% had normal resting but high normal or hypertensive exercise BPvalues. 7.4% of the subjects were high normal or hypertensive at restbut normotensive during exercise. Additional 5.9% had both high normalor hypertensive resting and exercise BP values.Exercise BP might be useful to identify white coat hypertension in a sub-group of young subjects. It is also relevant for the better determination ofcardiovascular risk using the proposed reference values for 12-17 year-oldsubjects. As long as prognostic data for reference values in adolescents aremissing, these statistical reference values might be useful in clinicalpractice

AB - In children and adolescents, office blood pressure (BP) is not very reliableand has a poor reproducibility. In case of adults, exercise BP correlatesmore closely with cardiovascular risk and there are cut-off values for ex-ercise BP which indicate normal and reference values. However, there re no reference values for children and adolescents, to date. The goal ofthe present investigation was a proposal for exercise BP reference valuesfor adolescents. In the Kiel EX.PRESS. (EXercise and PRESSure) study,systolic BP at rest and during exercise of 532 young subjects (aged 12-17 years) were determined. Systolic exercise BP was measured at 1.5Watt / kg body weight using a standardized cycle ergometer exercise test.Mean resting BP was 113.1±12.8 / 57.2±7.1 mmHg, while mean exercise BP was 149.9±19.8 / 54.2±8.6 mmHg. For the determination ofreference values, the German age-, height- and sex-related reference per-centiles for resting BP were used. The BP values at the 90th and the95th percentile were taken to determine the respective percentiles in ourstudy group. The corresponding percentiles were 87.6 and 92.1, thereforeaccording to German reference values which are very similar to interna-tional data 12.4% of the subjects had at least a high normal resting BPand 7.9% had hypertension. The systolic exercise BP values at these per-centiles for our sample are proposed as reference values for high normalexercise BP and exercise hypertension (see table 1). Using these referencevalues, 79% of our participants had normal resting and exercise BP values.7.8% had normal resting but high normal or hypertensive exercise BPvalues. 7.4% of the subjects were high normal or hypertensive at restbut normotensive during exercise. Additional 5.9% had both high normalor hypertensive resting and exercise BP values.Exercise BP might be useful to identify white coat hypertension in a sub-group of young subjects. It is also relevant for the better determination ofcardiovascular risk using the proposed reference values for 12-17 year-oldsubjects. As long as prognostic data for reference values in adolescents aremissing, these statistical reference values might be useful in clinicalpractice

M3 - Conference abstract in journal

VL - 8

SP - e60-e61

JO - J Am Soc Hypertens

JF - J Am Soc Hypertens

SN - 1933-1711

IS - 4

ER -