PortalPublikationenReduktion der Spättoxizität durch Amifostin bei fraktioniert...

Reduktion der Spättoxizität durch Amifostin bei fraktionierter Bestrahlung der Rattenspeicheldrüsen

Standard

Reduktion der Spättoxizität durch Amifostin bei fraktionierter Bestrahlung der Rattenspeicheldrüsen. / Sagowski, C; Wenzel, S; Jenicke, L; Bohuslavizki, K H; Kehrl, W; Zywietz, F; Roeser, K.

in: HNO, Jahrgang 50, Nr. 9, 09.2002, S. 822-8.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Sagowski, C, Wenzel, S, Jenicke, L, Bohuslavizki, KH, Kehrl, W, Zywietz, F & Roeser, K 2002, 'Reduktion der Spättoxizität durch Amifostin bei fraktionierter Bestrahlung der Rattenspeicheldrüsen', HNO, Jg. 50, Nr. 9, S. 822-8.

APA

Sagowski, C., Wenzel, S., Jenicke, L., Bohuslavizki, K. H., Kehrl, W., Zywietz, F., & Roeser, K. (2002). Reduktion der Spättoxizität durch Amifostin bei fraktionierter Bestrahlung der Rattenspeicheldrüsen. HNO, 50(9), 822-8.

Vancouver

Sagowski C, Wenzel S, Jenicke L, Bohuslavizki KH, Kehrl W, Zywietz F et al. Reduktion der Spättoxizität durch Amifostin bei fraktionierter Bestrahlung der Rattenspeicheldrüsen. HNO. 2002 Sep;50(9):822-8.

Bibtex

@article{b23a2bb380b74b56bef183a26bc075ed,
title = "Reduktion der Sp{\"a}ttoxizit{\"a}t durch Amifostin bei fraktionierter Bestrahlung der Rattenspeicheldr{\"u}sen",
abstract = "Clinical studies show that amifostine can reduce xerostomia and mucositis during radiotherapy of head and neck cancers. The aim of this study was to evaluate the radioprotective potency of amifostine with respect to late toxicity of salivary glands of rats. The head-neck-area of 8 male WAG/RijH rats (295 +/- 7 g) were irradiated with 60Co-gamma-rays (60 Gy/30 f/6 weeks). Amifostine (250 mg/m2 body surface) was applied via a venous port 15 min before each irradiation. Rats of a control group were irradiated with the same schedule with equal volumes of physiological saline. The morphological and sialoscintigraphical findings clearly demonstrate that amifostine has a remarkable cytoprotective effect on the late toxicity of irradiated salivary glands.",
keywords = "Amifostine, Animals, Cobalt Radioisotopes, Dose Fractionation, Dose-Response Relationship, Radiation, Male, Radiation Injuries, Experimental, Radiation-Protective Agents, Rats, Rats, Inbred Strains, Salivary Glands, Submandibular Gland, English Abstract, Journal Article",
author = "C Sagowski and S Wenzel and L Jenicke and Bohuslavizki, {K H} and W Kehrl and F Zywietz and K Roeser",
year = "2002",
month = sep,
language = "Deutsch",
volume = "50",
pages = "822--8",
journal = "HNO",
issn = "0017-6192",
publisher = "Springer",
number = "9",

}

RIS

TY - JOUR

T1 - Reduktion der Spättoxizität durch Amifostin bei fraktionierter Bestrahlung der Rattenspeicheldrüsen

AU - Sagowski, C

AU - Wenzel, S

AU - Jenicke, L

AU - Bohuslavizki, K H

AU - Kehrl, W

AU - Zywietz, F

AU - Roeser, K

PY - 2002/9

Y1 - 2002/9

N2 - Clinical studies show that amifostine can reduce xerostomia and mucositis during radiotherapy of head and neck cancers. The aim of this study was to evaluate the radioprotective potency of amifostine with respect to late toxicity of salivary glands of rats. The head-neck-area of 8 male WAG/RijH rats (295 +/- 7 g) were irradiated with 60Co-gamma-rays (60 Gy/30 f/6 weeks). Amifostine (250 mg/m2 body surface) was applied via a venous port 15 min before each irradiation. Rats of a control group were irradiated with the same schedule with equal volumes of physiological saline. The morphological and sialoscintigraphical findings clearly demonstrate that amifostine has a remarkable cytoprotective effect on the late toxicity of irradiated salivary glands.

AB - Clinical studies show that amifostine can reduce xerostomia and mucositis during radiotherapy of head and neck cancers. The aim of this study was to evaluate the radioprotective potency of amifostine with respect to late toxicity of salivary glands of rats. The head-neck-area of 8 male WAG/RijH rats (295 +/- 7 g) were irradiated with 60Co-gamma-rays (60 Gy/30 f/6 weeks). Amifostine (250 mg/m2 body surface) was applied via a venous port 15 min before each irradiation. Rats of a control group were irradiated with the same schedule with equal volumes of physiological saline. The morphological and sialoscintigraphical findings clearly demonstrate that amifostine has a remarkable cytoprotective effect on the late toxicity of irradiated salivary glands.

KW - Amifostine

KW - Animals

KW - Cobalt Radioisotopes

KW - Dose Fractionation

KW - Dose-Response Relationship, Radiation

KW - Male

KW - Radiation Injuries, Experimental

KW - Radiation-Protective Agents

KW - Rats

KW - Rats, Inbred Strains

KW - Salivary Glands

KW - Submandibular Gland

KW - English Abstract

KW - Journal Article

M3 - SCORING: Zeitschriftenaufsatz

C2 - 12425136

VL - 50

SP - 822

EP - 828

JO - HNO

JF - HNO

SN - 0017-6192

IS - 9

ER -