Reduced von Willebrand factor secretion is associated with loss of Weibel-Palade body formation.

  • G Castaman
  • S H Giacomelli
  • P M Jacobi
  • Tobias Obser
  • U Budde
  • F Rodeghiero
  • Reinhard Schneppenheim
  • S L Haberichter

Abstract

von Willebrand disease (VWD) is caused by mutations in von Willebrand factor (VWF) that have different pathophysiologic effect in causing low plasma VWF levels. Type 1 VWD includes quantitative plasma VWF deficiency with normal VWF structure and function.

Bibliografische Daten

OriginalspracheEnglisch
Aufsatznummer5
ISSN1538-7933
StatusVeröffentlicht - 2012
pubmed 22429825