Rapid-Antigen Test Negative Malaria in a Traveler Returning From Thailand, Molecularly Diagnosed as Plasmodium knowlesi

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Rapid-Antigen Test Negative Malaria in a Traveler Returning From Thailand, Molecularly Diagnosed as Plasmodium knowlesi. / Mackroth, Maria S; Tappe, Dennis; Tannich, Egbert; Addo, Marylyn; Rothe, Camilla.

in: OPEN FORUM INFECT DI, Jahrgang 3, Nr. 1, 01.2016, S. ofw039.

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@article{320ce858c9ac47609059318a6bd96a2d,
title = "Rapid-Antigen Test Negative Malaria in a Traveler Returning From Thailand, Molecularly Diagnosed as Plasmodium knowlesi",
abstract = "Plasmodium knowlesi has been identified in the last decade as a fifth species causing malaria in areas of South East Asia. Due to its short erythrocytic cycle, rapid development of high parasitemia and severe manifestations are frequently observed. Therefore, prompt diagnosis of infection is essential to prevent complications, but the low sensitivity of rapid diagnostic tests for P knowlesi pose a diagnostic challenge in acute settings. In this study, we report the case of a German traveler to Thailand, who was treated for P knowlesi malaria after returning to Germany. Rapid antigen test for malaria was negative on presentation. Diagnosis of a nonfalciparum malaria was made based on microscopy, and species definition was determined using polymerase chain reaction technique.",
author = "Mackroth, {Maria S} and Dennis Tappe and Egbert Tannich and Marylyn Addo and Camilla Rothe",
year = "2016",
month = jan,
doi = "10.1093/ofid/ofw039",
language = "English",
volume = "3",
pages = "ofw039",
journal = "OPEN FORUM INFECT DI",
issn = "2328-8957",
publisher = "Oxford University Press",
number = "1",

}

RIS

TY - JOUR

T1 - Rapid-Antigen Test Negative Malaria in a Traveler Returning From Thailand, Molecularly Diagnosed as Plasmodium knowlesi

AU - Mackroth, Maria S

AU - Tappe, Dennis

AU - Tannich, Egbert

AU - Addo, Marylyn

AU - Rothe, Camilla

PY - 2016/1

Y1 - 2016/1

N2 - Plasmodium knowlesi has been identified in the last decade as a fifth species causing malaria in areas of South East Asia. Due to its short erythrocytic cycle, rapid development of high parasitemia and severe manifestations are frequently observed. Therefore, prompt diagnosis of infection is essential to prevent complications, but the low sensitivity of rapid diagnostic tests for P knowlesi pose a diagnostic challenge in acute settings. In this study, we report the case of a German traveler to Thailand, who was treated for P knowlesi malaria after returning to Germany. Rapid antigen test for malaria was negative on presentation. Diagnosis of a nonfalciparum malaria was made based on microscopy, and species definition was determined using polymerase chain reaction technique.

AB - Plasmodium knowlesi has been identified in the last decade as a fifth species causing malaria in areas of South East Asia. Due to its short erythrocytic cycle, rapid development of high parasitemia and severe manifestations are frequently observed. Therefore, prompt diagnosis of infection is essential to prevent complications, but the low sensitivity of rapid diagnostic tests for P knowlesi pose a diagnostic challenge in acute settings. In this study, we report the case of a German traveler to Thailand, who was treated for P knowlesi malaria after returning to Germany. Rapid antigen test for malaria was negative on presentation. Diagnosis of a nonfalciparum malaria was made based on microscopy, and species definition was determined using polymerase chain reaction technique.

U2 - 10.1093/ofid/ofw039

DO - 10.1093/ofid/ofw039

M3 - SCORING: Journal article

C2 - 27006963

VL - 3

SP - ofw039

JO - OPEN FORUM INFECT DI

JF - OPEN FORUM INFECT DI

SN - 2328-8957

IS - 1

ER -