Randomized clinical trial of the influence of intraperitoneal local anaesthesia on pain after laparoscopic surgery

D Palmes; S Röttgermann; C Classen; J Haier; R Horstmann

doi:10.1002/bjs.5810

Randomized clinical trial of the influence of intraperitoneal local anaesthesia on pain after laparoscopic surgery

Standard

Randomized clinical trial of the influence of intraperitoneal local anaesthesia on pain after laparoscopic surgery. / Palmes, D; Röttgermann, S; Classen, C; Haier, J; Horstmann, R.

in: BRIT J SURG, Jahrgang 94, Nr. 7, 07.2007, S. 824-32.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Palmes, D, Röttgermann, S, Classen, C, Haier, J & Horstmann, R 2007, 'Randomized clinical trial of the influence of intraperitoneal local anaesthesia on pain after laparoscopic surgery', BRIT J SURG, Jg. 94, Nr. 7, S. 824-32. https://doi.org/10.1002/bjs.5810

APA

Palmes, D., Röttgermann, S., Classen, C., Haier, J., & Horstmann, R. (2007). Randomized clinical trial of the influence of intraperitoneal local anaesthesia on pain after laparoscopic surgery. BRIT J SURG, 94(7), 824-32. https://doi.org/10.1002/bjs.5810

Vancouver

Palmes D, Röttgermann S, Classen C, Haier J, Horstmann R. Randomized clinical trial of the influence of intraperitoneal local anaesthesia on pain after laparoscopic surgery. BRIT J SURG. 2007 Jul;94(7):824-32. https://doi.org/10.1002/bjs.5810

Bibtex

@article{db9bda863f7d4943920a4ea8b2257314,

title = "Randomized clinical trial of the influence of intraperitoneal local anaesthesia on pain after laparoscopic surgery",

abstract = "BACKGROUND: There is controversy about the effectiveness of intraperitoneal local anaesthesia (LA) in laparoscopic surgery. The aim of the present randomized clinical trial was to compare the analgesic effect of pre-emptive (preoperative) versus postoperative intraperitoneal LA in two different types of laparoscopic surgery.METHODS: Between July 2004 and January 2005, 133 consecutive patients scheduled to undergo laparoscopic fundoplication or hernia repair were randomly assigned to one of three treatments: placebo solution (50 ml 0.9 per cent saline) or LA (50 ml 0.5 per cent lidocaine) administered immediately after creation of the pneumoperitoneum, or LA (50 ml 0.5 per cent lidocaine) at the end of the operation. Analgesic requirements were analysed, and pain was assessed using a visual analogue scale (VAS) from 0 to 100 at 6, 12, 24 and 48 h after surgery.RESULTS: The duration of pneumoperitoneum (median 66 versus 46 min respectively; P < 0.001) and overall pain intensity (median VAS score 46.7 versus 6.5; P < 0.001) were higher for laparoscopic fundoplication than for hernia repair. Preoperative application of LA reduced abdominal pain (median 28.6 versus 74.9; P < 0.005), shoulder pain (median 24.3 versus 43.8; P = 0.004) and analgesic consumption (mean(s.d.) 11.1(5.0) versus 18.5(5.4) mg piritramide per 48 h; P = 0.002) after fundoplication, but had no analgesic effects after hernia repair.CONCLUSION: Pre-emptive application of LA reduced postoperative pain and analgesic requirements after laparoscopic fundoplication.",

keywords = "Administration, Topical, Adult, Aged, Analgesics, Anesthesia, General, Anesthesia, Local, Female, Fundoplication, Gastroesophageal Reflux, Herniorrhaphy, Humans, Laparoscopy, Male, Middle Aged, Pain Measurement, Pain, Postoperative, Pneumoperitoneum, Artificial, Preoperative Care, Shoulder Pain, Treatment Outcome",

author = "D Palmes and S R{\"o}ttgermann and C Classen and J Haier and R Horstmann",

year = "2007",

month = jul,

doi = "10.1002/bjs.5810",

language = "English",

volume = "94",

pages = "824--32",

journal = "BRIT J SURG",

issn = "0007-1323",

publisher = "John Wiley and Sons Ltd",

number = "7",

}

RIS

TY - JOUR

T1 - Randomized clinical trial of the influence of intraperitoneal local anaesthesia on pain after laparoscopic surgery

AU - Palmes, D

AU - Röttgermann, S

AU - Classen, C

AU - Haier, J

AU - Horstmann, R

PY - 2007/7

Y1 - 2007/7

N2 - BACKGROUND: There is controversy about the effectiveness of intraperitoneal local anaesthesia (LA) in laparoscopic surgery. The aim of the present randomized clinical trial was to compare the analgesic effect of pre-emptive (preoperative) versus postoperative intraperitoneal LA in two different types of laparoscopic surgery.METHODS: Between July 2004 and January 2005, 133 consecutive patients scheduled to undergo laparoscopic fundoplication or hernia repair were randomly assigned to one of three treatments: placebo solution (50 ml 0.9 per cent saline) or LA (50 ml 0.5 per cent lidocaine) administered immediately after creation of the pneumoperitoneum, or LA (50 ml 0.5 per cent lidocaine) at the end of the operation. Analgesic requirements were analysed, and pain was assessed using a visual analogue scale (VAS) from 0 to 100 at 6, 12, 24 and 48 h after surgery.RESULTS: The duration of pneumoperitoneum (median 66 versus 46 min respectively; P < 0.001) and overall pain intensity (median VAS score 46.7 versus 6.5; P < 0.001) were higher for laparoscopic fundoplication than for hernia repair. Preoperative application of LA reduced abdominal pain (median 28.6 versus 74.9; P < 0.005), shoulder pain (median 24.3 versus 43.8; P = 0.004) and analgesic consumption (mean(s.d.) 11.1(5.0) versus 18.5(5.4) mg piritramide per 48 h; P = 0.002) after fundoplication, but had no analgesic effects after hernia repair.CONCLUSION: Pre-emptive application of LA reduced postoperative pain and analgesic requirements after laparoscopic fundoplication.

AB - BACKGROUND: There is controversy about the effectiveness of intraperitoneal local anaesthesia (LA) in laparoscopic surgery. The aim of the present randomized clinical trial was to compare the analgesic effect of pre-emptive (preoperative) versus postoperative intraperitoneal LA in two different types of laparoscopic surgery.METHODS: Between July 2004 and January 2005, 133 consecutive patients scheduled to undergo laparoscopic fundoplication or hernia repair were randomly assigned to one of three treatments: placebo solution (50 ml 0.9 per cent saline) or LA (50 ml 0.5 per cent lidocaine) administered immediately after creation of the pneumoperitoneum, or LA (50 ml 0.5 per cent lidocaine) at the end of the operation. Analgesic requirements were analysed, and pain was assessed using a visual analogue scale (VAS) from 0 to 100 at 6, 12, 24 and 48 h after surgery.RESULTS: The duration of pneumoperitoneum (median 66 versus 46 min respectively; P < 0.001) and overall pain intensity (median VAS score 46.7 versus 6.5; P < 0.001) were higher for laparoscopic fundoplication than for hernia repair. Preoperative application of LA reduced abdominal pain (median 28.6 versus 74.9; P < 0.005), shoulder pain (median 24.3 versus 43.8; P = 0.004) and analgesic consumption (mean(s.d.) 11.1(5.0) versus 18.5(5.4) mg piritramide per 48 h; P = 0.002) after fundoplication, but had no analgesic effects after hernia repair.CONCLUSION: Pre-emptive application of LA reduced postoperative pain and analgesic requirements after laparoscopic fundoplication.

KW - Administration, Topical

KW - Adult

KW - Aged

KW - Analgesics

KW - Anesthesia, General

KW - Anesthesia, Local

KW - Female

KW - Fundoplication

KW - Gastroesophageal Reflux

KW - Herniorrhaphy

KW - Humans

KW - Laparoscopy

KW - Male

KW - Middle Aged

KW - Pain Measurement

KW - Pain, Postoperative

KW - Pneumoperitoneum, Artificial

KW - Preoperative Care

KW - Shoulder Pain

KW - Treatment Outcome

U2 - 10.1002/bjs.5810

DO - 10.1002/bjs.5810

M3 - SCORING: Journal article

C2 - 17571296

VL - 94

SP - 824

EP - 832

JO - BRIT J SURG

JF - BRIT J SURG

SN - 0007-1323

IS - 7

ER -